Literature DB >> 15965598

In vitro properties of PLLA screws and novel bioabsorbable implant with elastic nucleus to replace intervertebral disc.

V Ellä1, M Kellomäki, P Törmälä.   

Abstract

The suitability of two different implant types for the replacement of the intervertebral disc was studied in vitro. Self-reinforced poly-L-lactide (SR-PLLA) screws Ø 4.5 mm were studied 24 weeks in vitro and cylindrical implants with elastic nucleus made of poly(L/D)lactide 96/4, poly(L/DL)lactide 70/30, Bioactive Glass n:o 13-93 and Polyactive 1000PEOT70PBT30 were studied 15 weeks in vitro. The cylindrical implant mimics the size and shape of the intervertebral disc. During the in vitro, there were no changes in compression properties with either implant types. The screws had sufficient modulus for intervertebral ossification in the canine model and the cylindrical implant showed also sufficient mechanical properties. These results suggest that both implant types could be used in clinical testing.

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Year:  2005        PMID： 15965598     DOI： 10.1007/s10856-005-2537-1

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN： 0957-4530            Impact factor:   3.896


  15 in total

1.  Bioactive glass serves as a substrate for maintenance of phenotype of nucleus pulposus cells of the intervertebral disc.

Authors:  J C Gan; P Ducheyne; E Vresilovic; I M Shapiro
Journal:  J Biomed Mater Res       Date:  2000-09-15

2.  Strength retention of self-reinforced poly-L-lactide screws. A comparison of compression moulded and machine cut screws.

Authors:  T Pohjonen; P Helevirta; P Törmälä; K Koskikare; H Pätiälä; P Rokkanen
Journal:  J Mater Sci Mater Med       Date:  1997-05       Impact factor: 3.896

3.  Strength and stability of posterior lumbar interbody fusion. Comparison of titanium fiber mesh implant and tricortical bone graft.

Authors:  K Hoshijima; R W Nightingale; J R Yu; W J Richardson; K D Harper; H Yamamoto; B S Myers
Journal:  Spine (Phila Pa 1976)       Date:  1997-06-01       Impact factor: 3.468

Review 4.  Materials and design of spinal implants--a review.

Authors:  E O Martz; V K Goel; M H Pope; J B Park
Journal:  J Biomed Mater Res       Date:  1997

5.  Anterior cervical interbody fusion with hydroxyapatite graft and plate system.

Authors:  M Bruneau; J F Nisolle; C Gilliard; T Gustin
Journal:  Neurosurg Focus       Date:  2001-04-15       Impact factor: 4.047

6.  Mechanical evaluation of a canine intervertebral disc spacer: in situ and in vivo studies.

Authors:  M Vuono-Hawkins; M C Zimmerman; C K Lee; F M Carter; J R Parsons; N A Langrana
Journal:  J Orthop Res       Date:  1994-01       Impact factor: 3.494

Review 7.  Bioabsorbable fixation in orthopaedic surgery and traumatology.

Authors:  P U Rokkanen; O Böstman; E Hirvensalo; E A Mäkelä; E K Partio; H Pätiälä; S I Vainionpää; K Vihtonen; P Törmälä
Journal:  Biomaterials       Date:  2000-12       Impact factor: 12.479

8.  Effect of in vivo and in vitro degradation on molecular and mechanical properties of various low-molecular-weight polylactides.

Authors:  P Mainil-Varlet; R Curtis; S Gogolewski
Journal:  J Biomed Mater Res       Date:  1997-09-05

9.  Bioabsorbable polymer plates coated with bioactive glass spheres.

Authors:  H Niiranen; P Törmälä
Journal:  J Mater Sci Mater Med       Date:  1999-12       Impact factor: 3.896

10.  Long-term follow-up of lower lumbar fusion patients.

Authors:  T R Lehmann; K F Spratt; J E Tozzi; J N Weinstein; S J Reinarz; G Y el-Khoury; H Colby
Journal:  Spine (Phila Pa 1976)       Date:  1987-03       Impact factor: 3.468
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  2 in total

Review 1.  Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering.

Authors:  Ganesh Narayanan; Varadraj N Vernekar; Emmanuel L Kuyinu; Cato T Laurencin
Journal:  Adv Drug Deliv Rev       Date:  2016-04-25       Impact factor: 15.470

2.  Structural characterization of poly-l-lactic acid (P(L)LA) and poly(glycolic acid)(PGA) oligomers.

Authors:  Tommaso Casalini; Filippo Rossi; Marco Santoro; Giuseppe Perale
Journal:  Int J Mol Sci       Date:  2011-06-10       Impact factor: 5.923
  2 in total

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