Strength retention of self-reinforced poly-L-lactide screws. A comparison of compression moulded and machine cut screws.

The effect of the manufacturing method on the strength retention of self-reinforced poly-L-lactide (SR-PLLA) screws was studied in vitro and in vivo from 3 up to at least 15 weeks. SR-PLLA screws were manufactured from axially oriented SR-PLLA billets by the conventional compression moulding process and an in-house developed machine cutting technique. New machined SR-PLLA screws (thread diameters 4.5 mm and 3.5 mm) were significantly stronger than older compression moulded SR-PLLA screws (4.5 mm and 3.5 mm) in bending and torque strength tests but significantly weaker in shear strength tests. In pull out tests there were not significant strength differences between the screws. Mechanical analysis and molecular weight measurements confirmed earlier observations that SR-PLLA degrades faster in vivo than in vitro. These results suggest that the new screws could be suitable for clinical use.