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Literature DB >> 15965240

Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster.

Zhenzhong Chen¹, Katherine R Smith, Philip Batterham, Charles Robin.

Abstract

Smg1 is a key component of nonsense-mediated decay (NMD) in Caenorhabditis elegans and mammals. Here we report that two nonsense alleles of the ortholog of Smg1 do not affect NMD in Drosophila melanogaster.

Entities: Gene Species

Mesh：

Substances：

Year: 2005 PMID： 15965240 PMCID： PMC1456532 DOI： 10.1534/genetics.105.045674

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

13 in total

1. FAT: a novel domain in PIK-related kinases.

Authors: R Bosotti; A Isacchi; E L Sonnhammer
Journal: Trends Biochem Sci Date: 2000-05 Impact factor: 13.807

2. Nonsense-mediated mRNA decay.

Authors: Lynne E Maquat
Journal: Curr Biol Date: 2002-03-19 Impact factor: 10.834

Review 3. Curbing the nonsense: the activation and regulation of mRNA surveillance.

Authors: C J Wilusz; W Wang; S W Peltz
Journal: Genes Dev Date: 2001-11-01 Impact factor: 11.361

4. A genetic analysis of cyromazine resistance in Drosophila melanogaster (Diptera: Drosophilidae).

Authors: P J Daborn; J A McKenzie; P Batterham
Journal: J Econ Entomol Date: 2000-06 Impact factor: 2.381

5. Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.

Authors: S Brogna
Journal: RNA Date: 1999-04 Impact factor: 4.942

6. A new kind of informational suppression in the nematode Caenorhabditis elegans.

Authors: J Hodgkin; A Papp; R Pulak; V Ambros; P Anderson
Journal: Genetics Date: 1989-10 Impact factor: 4.562

7. Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.

Authors: A Yamashita; T Ohnishi; I Kashima; Y Taya; S Ohno
Journal: Genes Dev Date: 2001-09-01 Impact factor: 11.361

8. mRNA surveillance by the Caenorhabditis elegans smg genes.

Authors: R Pulak; P Anderson
Journal: Genes Dev Date: 1993-10 Impact factor: 11.361

9. Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways.

Authors: David Gatfield; Leonie Unterholzner; Francesca D Ciccarelli; Peer Bork; Elisa Izaurralde
Journal: EMBO J Date: 2003-08-01 Impact factor: 11.598

10. Cyromazine resistance in Drosophila melanogaster (Diptera: Drosophilidae) generated by ethyl methanesulfonate mutagenesis.

Authors: G J Adcock; P Batterham; L E Kelly; J A McKenzie
Journal: J Econ Entomol Date: 1993-08 Impact factor: 2.381

15 in total

1. The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.

Authors: A Ashleigh Long; Cecon T Mahapatra; Elvin A Woodruff; Jeff Rohrbough; Hung-Tat Leung; Shikoh Shino; Lingling An; Rebecca W Doerge; Mark M Metzstein; William L Pak; Kendal Broadie
Journal: J Cell Sci Date: 2010-09-07 Impact factor: 5.285

2. Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets.

Authors: Jan Rehwinkel; Ivica Letunic; Jeroen Raes; Peer Bork; Elisa Izaurralde
Journal: RNA Date: 2005-10 Impact factor: 4.942

3. Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII.

Authors: Yongjun Dang; Woon-Kai Low; Jing Xu; Niels H Gehring; Harry C Dietz; Daniel Romo; Jun O Liu
Journal: J Biol Chem Date: 2009-07-01 Impact factor: 5.157

Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster.

1. FAT: a novel domain in PIK-related kinases.

2. Nonsense-mediated mRNA decay.

Review 3. Curbing the nonsense: the activation and regulation of mRNA surveillance.

4. A genetic analysis of cyromazine resistance in Drosophila melanogaster (Diptera: Drosophilidae).

5. Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.

6. A new kind of informational suppression in the nematode Caenorhabditis elegans.

7. Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.

8. mRNA surveillance by the Caenorhabditis elegans smg genes.

9. Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways.

10. Cyromazine resistance in Drosophila melanogaster (Diptera: Drosophilidae) generated by ethyl methanesulfonate mutagenesis.

1. The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.

2. Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets.

3. Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII.

Review 4. Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question.

5. Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes.

6. Multiple Nonsense-Mediated mRNA Processes Require Smg5 in Drosophila.

Review 7. The multiple lives of NMD factors: balancing roles in gene and genome regulation.

8. Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6.

9. Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster.

Review 10. Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2.