Fischer's Fused Full Field Digital Mammography and Ultrasound System (FFDMUS).

It has been well established that X-ray modality when combined with ultrasound modality increases sensitivity and specificity of breast lesion detections. Under the NIH grant, Fischer has developed a fused full-field digital mammography and ultrasound system (FFDMUS), which has ability to acquire 2-D X-ray mammogram and 3-D ultrasound images simultaneously. This novel technology generates co-registered breast images of X-ray and ultrasound images. The co-registration error between X-ray and ultrasound images acquired is within 2.00 mm in scan direction, and is 0.5 mm in anterior-posterior direction. We did the performance evaluation of the system, and concluded that the ultrasound image qualities from FFDMUS and Hand-held ultrasound (HHUS) are comparable, and the X-ray image qualities from FFDMUS and SenoScan(R) are also comparable. We also developed a preliminary CAD registration and segmentation system for FFDMUS datasets.