Literature DB >> 15900321

Artificial metallonucleases.

Fabrizio Mancin1, Paolo Scrimin, Paolo Tecilla, Umberto Tonellato.   

Abstract

The development of synthetic agents able to hydrolytically cleave DNA with high efficiency and selectivity is a fascinating challenge that will show the way to obtaining artificial nucleases able to compete with the natural enzymes. This Feature Article highlights the progress reported toward the realization of synthetic nucleases with particular attention to the strategies that can be pursued to improve efficiency and sequence selectivity.

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Year:  2005        PMID： 15900321     DOI： 10.1039/b418164f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  17 in total

1.  Nuclease activity via self-activation and anticancer activity of a mononuclear copper(II) complex: novel role of the tertiary butyl group in the ligand frame.

Authors:  Kaushik Ghosh; Pramod Kumar; Varun Mohan; Udai P Singh; Sahba Kasiri; Subhrangsu S Mandal
Journal:  Inorg Chem       Date:  2012-02-28       Impact factor: 5.165

Review 2.  Protein design: toward functional metalloenzymes.

Authors:  Fangting Yu; Virginia M Cangelosi; Melissa L Zastrow; Matteo Tegoni; Jefferson S Plegaria; Alison G Tebo; Catherine S Mocny; Leela Ruckthong; Hira Qayyum; Vincent L Pecoraro
Journal:  Chem Rev       Date:  2014-03-24       Impact factor: 60.622

3.  Targeting an Artificial Metal Nuclease to DNA by a Simple Chemical Modification and Its Drastic Effect on Catalysis.

Authors:  Nathalia Castilho; Philipe Gabriel; Tiago Pacheco Camargo; Ademir Neves; Hernán Terenzi
Journal:  ACS Med Chem Lett       Date:  2019-08-12       Impact factor: 4.345

4.  Screening organometallic thiophene containing thiosemicarbazone ruthenium (II/III) complexes as potential anti-tumour agents.

Authors:  Zehra Tavsan; Pelin Köse Yaman; Elif Subasi; Hulya Ayar Kayali
Journal:  J Biol Inorg Chem       Date:  2018-03-22       Impact factor: 3.358

5.  Self-assembled gold nanocrystal micelles act as an excellent artificial nanozyme with ribonuclease activity.

Authors:  Zhiming Zhang; Qiuan Fu; Xiangqiu Li; Xin Huang; Jiayun Xu; Jiacong Shen; Junqiu Liu
Journal:  J Biol Inorg Chem       Date:  2009-02-21       Impact factor: 3.358

6.  Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle.

Authors:  Ta-Sheng Andrew Tseng; Judith N Burstyn
Journal:  Chem Commun (Camb)       Date:  2008-10-27       Impact factor: 6.222

Review 7.  Metal complexes promoting catalytic cleavage of nucleic acids-biochemical tools and therapeutics.

Authors:  Zhen Yu; J A Cowan
Journal:  Curr Opin Chem Biol       Date:  2017-11-15       Impact factor: 8.822

8.  Luminescent Behavior of Ru(II) Polypyridyl Morpholine Complexes, Synthesis, Characterization, DNA, Protein Binding, Sensor Effect of Ions/Solvents and Docking Studies.

Authors:  Ravi Kumar Vuradi; Venkat Reddy Putta; Deepika Nancherla; Satyanarayana Sirasani
Journal:  J Fluoresc       Date:  2015-12-26       Impact factor: 2.217

9.  Chemical modification of Ce(IV)/EDTA-based artificial restriction DNA cutter for versatile manipulation of double-stranded DNA.

Authors:  Yoji Yamamoto; Masao Mori; Yuichiro Aiba; Takafumi Tomita; Wen Chen; Jing-Min Zhou; Akihiko Uehara; Yi Ren; Yoshihito Kitamura; Makoto Komiyama
Journal:  Nucleic Acids Res       Date:  2007-03-21       Impact factor: 16.971

10.  DNA-catalyzed sequence-specific hydrolysis of DNA.

Authors:  Madhavaiah Chandra; Amit Sachdeva; Scott K Silverman
Journal:  Nat Chem Biol       Date:  2009-08-16       Impact factor: 15.040
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