Literature DB >> 19082122

Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle.

Ta-Sheng Andrew Tseng1, Judith N Burstyn.   

Abstract

An intercalator-linked macrocycle 3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane]hexyl) acridinium bromide was synthesized, its copper(ii) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9]aneN(3))(2+) complex.

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Year:  2008        PMID： 19082122      PMCID： PMC5989323          DOI： 10.1039/b812183d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Sequence-selective and hydrolytic cleavage of DNA by zinc finger mutants.

Authors:  Akiko Nomura; Yukio Sugiura
Journal:  J Am Chem Soc       Date:  2004-12-01       Impact factor: 15.419

Review 2.  Artificial metallonucleases.

Authors:  Fabrizio Mancin; Paolo Scrimin; Paolo Tecilla; Umberto Tonellato
Journal:  Chem Commun (Camb)       Date:  2005-02-22       Impact factor: 6.222

3.  Triisopropyltriazacyclononane copper(II): an efficient phosphodiester hydrolysis catalyst and DNA cleavage agent.

Authors:  Kathryn M Deck; T Andrew Tseng; Judith N Burstyn
Journal:  Inorg Chem       Date:  2002-02-25       Impact factor: 5.165

4.  Efficient plasmid DNA cleavage by a mononuclear copper(II) complex.

Authors:  Claudia Sissi; Fabrizio Mancin; Maddalena Gatos; Manlio Palumbo; Paolo Tecilla; Umberto Tonellato
Journal:  Inorg Chem       Date:  2005-04-04       Impact factor: 5.165

5.  Effect of a conjugated acridine moiety on the binding and reactivity of Cu(II)[9-acridinylmethyl-1,4,7-triazacyclononane] with DNA.

Authors:  Tomoya Hirohama; Hidekazu Arii; Makoto Chikira
Journal:  J Inorg Biochem       Date:  2004-11       Impact factor: 4.155

6.  Double-stranded cleavage of pBR322 by a diiron complex via a "hydrolytic" mechanism.

Authors:  L M Schnaith; R S Hanson; L Que
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

7.  Bis(dipyridophenazine)copper(II) complex as major groove directing synthetic hydrolase.

Authors:  Tarkeshwar Gupta; Shanta Dhar; Munirathinam Nethaji; Akhil R Chakravarty
Journal:  Dalton Trans       Date:  2004-05-21       Impact factor: 4.390

8.  Toward efficient Zn(II)-based artificial nucleases.

Authors:  Elisa Boseggia; Maddalena Gatos; Lorena Lucatello; Fabrizio Mancin; Stefano Moro; Manlio Palumbo; Claudia Sissi; Paolo Tecilla; Umberto Tonellato; Giuseppe Zagotto
Journal:  J Am Chem Soc       Date:  2004-04-14       Impact factor: 15.419
  8 in total
  3 in total

1.  Catalytic nanomedicine technology: copper complexes loaded on titania nanomaterials as cytotoxic agents of cancer cell.

Authors:  Tessy Lopez; Emma Ortiz-Islas; Patricia Guevara; Esteban Gómez
Journal:  Int J Nanomedicine       Date:  2013-02-09

2.  Singlet oxygen mediated DNA degradation by copper nanoparticles: potential towards cytotoxic effect on cancer cells.

Authors:  Gregor P Jose; Subhankar Santra; Swadhin K Mandal; Tapas K Sengupta
Journal:  J Nanobiotechnology       Date:  2011-03-25       Impact factor: 10.435

3.  Core-Shell Nanostructured Fe3O4-Poly(styrene-co-vinylbenzyl chloride) Grafted PPI Dendrimers Stabilized with AuNPs/PdNPs for Efficient Nuclease Activity.

Authors:  Eagambaram Murugan; Nimita Jebaranjitham J; Mathivathanan Ariraman; Saravanan Rajendran; Janankiraman Kathirvel; C R Akshata; Kalpana Kumar
Journal:  ACS Omega       Date:  2018-10-19
  3 in total

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