Xiaoming Bi1, Debiao Li. 1. Department of Radiology, Northwestern University, Chicago, Illinois, USA.
Abstract
PURPOSE: To evaluate the efficacy of contrast-enhanced coronary magnetic resonance angiography (MRA) at 3.0 T. MATERIALS AND METHODS: Nine healthy human volunteers were studied on a 3.0-T whole-body MR system. A three-dimensional, breathhold, magnetization-prepared, segmented, gradient-echo sequence was used, with injection of 20 mL gadopentetate dimeglumine for each three-dimensional slab. Imaging parameters were optimized based on computer simulations. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), depicted coronary artery length, lumen diameter, and imaging sharpness with contrast agent were evaluated. SNR and CNR were compared to the results from a previous 1.5-T study. RESULTS: A 53% increment in SNR and a 305% enhancement in CNR were measured with contrast. Vessel length and sharpness depicted were higher and the lumen diameter was lower (all P values < 0.05) in postcontrast images. Compared to previous results from 1.5-T, the SNR, CNR, and vessel sharpness were enhanced at 3.0 T with higher spatial resolution. CONCLUSION: Contrast-enhanced, three-dimensional, coronary MRA at 3.0 T is a promising technique for diagnosing coronary artery diseases. Patient studies are necessary to evaluate its clinical utility. (c) 2005 Wiley-Liss, Inc.
PURPOSE: To evaluate the efficacy of contrast-enhanced coronary magnetic resonance angiography (MRA) at 3.0 T. MATERIALS AND METHODS: Nine healthy human volunteers were studied on a 3.0-T whole-body MR system. A three-dimensional, breathhold, magnetization-prepared, segmented, gradient-echo sequence was used, with injection of 20 mL gadopentetate dimeglumine for each three-dimensional slab. Imaging parameters were optimized based on computer simulations. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), depicted coronary artery length, lumen diameter, and imaging sharpness with contrast agent were evaluated. SNR and CNR were compared to the results from a previous 1.5-T study. RESULTS: A 53% increment in SNR and a 305% enhancement in CNR were measured with contrast. Vessel length and sharpness depicted were higher and the lumen diameter was lower (all P values < 0.05) in postcontrast images. Compared to previous results from 1.5-T, the SNR, CNR, and vessel sharpness were enhanced at 3.0 T with higher spatial resolution. CONCLUSION: Contrast-enhanced, three-dimensional, coronary MRA at 3.0 T is a promising technique for diagnosing coronary artery diseases. Patient studies are necessary to evaluate its clinical utility. (c) 2005 Wiley-Liss, Inc.
Authors: Peng Hu; Jonathan Chan; Long H Ngo; Jouke Smink; Beth Goddu; Kraig V Kissinger; Lois Goepfert; Thomas H Hauser; Neil M Rofsky; Warren J Manning; Reza Nezafat Journal: Magn Reson Med Date: 2010-11-30 Impact factor: 4.668
Authors: Saskia G C van Elderen; Maarten J Versluis; Jos J M Westenberg; Harsh Agarwal; Nadine B Smith; Matthias Stuber; Albert de Roos; Andrew G Webb Journal: Radiology Date: 2010-10 Impact factor: 11.105
Authors: Peng Hu; Michael L Chuang; Long H Ngo; Christian T Stoeck; Dana C Peters; Kraig V Kissinger; Beth Goddu; Lois A Goepfert; Warren J Manning; Reza Nezafat Journal: Radiology Date: 2010-02 Impact factor: 11.105