Literature DB >> 1566332

LIF: lots of interesting functions.

D J Hilton1.   

Abstract

Leukaemia inhibitory factor (LIF) is one of a growing number of cytokines that cannot be readily categorized according to its functions. Rather, these pleiotropic hormones have diverse and often overlapping effects on a multitude of cell types: for example, LIF can inhibit the differentiation of embryonal stem cells on one hand and induce the differentiation of M1 leukaemic cells on the other. Recent work has shed light on the physiological effects of LIF, how these are limited, and the biochemical and biological properties of LIF and its receptor.

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Year:  1992        PMID: 1566332     DOI: 10.1016/0968-0004(92)90505-4

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  32 in total

Review 1.  Cytokines and their receptors in cardiovascular diseases--role of gp130 signalling pathway in cardiac myocyte growth and maintenance.

Authors:  K Yamauchi-Takihara; T Kishimoto
Journal:  Int J Exp Pathol       Date:  2000-02       Impact factor: 1.925

2.  A mass spectrometric journey into protein and proteome research.

Authors:  Ruedi Aebersold
Journal:  J Am Soc Mass Spectrom       Date:  2003-07       Impact factor: 3.109

Review 3.  Chemotherapy-induced peripheral neuropathy: clinical features, diagnosis, prevention and treatment strategies.

Authors:  Gerardo Gutiérrez-Gutiérrez; María Sereno; Ambrosio Miralles; Enrique Casado-Sáenz; Eduardo Gutiérrez-Rivas
Journal:  Clin Transl Oncol       Date:  2010-02       Impact factor: 3.405

4.  Introduction of precise alterations into the mouse genome with high efficiency by stable tag-exchange gene targeting: implications for gene targeting in ES cells.

Authors:  L M Whyatt; P D Rathjen
Journal:  Nucleic Acids Res       Date:  1997-06-15       Impact factor: 16.971

5.  LIF receptor-gp130 interaction investigated by homology modeling: implications for LIF binding.

Authors:  D K Smith; H R Treutlein
Journal:  Protein Sci       Date:  1998-04       Impact factor: 6.725

6.  Identification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor.

Authors:  S Thiel; I Behrmann; A Timmermann; H Dahmen; G Müller-Newen; F Schaper; J Tavernier; V Pitard; P C Heinrich; L Graeve
Journal:  Biochem J       Date:  1999-04-01       Impact factor: 3.857

7.  Involving of the cytoplasmic region of leukemia inhibitory factor receptor alpha subunit, IL-6 related signal transducer-gp130 or fas death domain for MAPK p42/44 activation in HL-60 cell with LIF or anti-Fas IgG.

Authors:  H Liu; J Dan; S Tang; S Wu
Journal:  Mol Cell Biochem       Date:  2001-01       Impact factor: 3.396

8.  Growth factor/cytokine secretion by a permanent human endometrial cell line with embryotrophic properties.

Authors:  N N Desai; J M Goldfarb
Journal:  J Assist Reprod Genet       Date:  1996-08       Impact factor: 3.412

Review 9.  IL-6 cytokine family and signal transduction: a model of the cytokine system.

Authors:  M Hibi; K Nakajima; T Hirano
Journal:  J Mol Med (Berl)       Date:  1996-01       Impact factor: 4.599

10.  Inhibited gastrulation in mouse embryos overexpressing the leukemia inhibitory factor.

Authors:  F Conquet; N Peyriéras; L Tiret; P Brûlet
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

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