Literature DB >> 1563775

Nucleotide sequence of the ospAB operon of a Borrelia burgdorferi strain expressing OspA but not OspB.

H Eiffert1, A Ohlenbusch, W Fehling, H Lotter, R Thomssen.   

Abstract

The nucleotide sequence of a 1.6-kb clone containing the gene for outer surface protein A (OspA) of a German strain (GO2) of Borrelia burgdorferi was determined. The deduced amino acid sequence showed a homology of 82% to the OspA molecules from three other B. burgdorferi strains. The best-conserved region was recognized at the 36-amino-terminal amino acids of OspA. OspB could not be identified in the strain investigated, probably because the nucleotide sequence of the ospAB operon prevented expression of the OspB gene.

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Year:  1992        PMID： 1563775      PMCID： PMC257086          DOI： 10.1128/iai.60.5.1864-1868.1992

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  33 in total

1.  Characterization of the protective antibody response to Borrelia burgdorferi in experimentally infected LSH hamsters.

Authors:  J L Schmitz; R F Schell; S D Lovrich; S M Callister; J E Coe
Journal:  Infect Immun       Date:  1991-06       Impact factor: 3.441

2.  Cloning and sequencing of the gene encoding the outer surface protein A (OspA) of a European Borrelia burgdorferi isolate.

Authors:  R Wallich; U E Schaible; M M Simon; A Heiberger; M D Kramer
Journal:  Nucleic Acids Res       Date:  1989-11-11       Impact factor: 16.971

3.  Characterization of a tick isolate of Borrelia burgdorferi that possesses a major low-molecular-weight surface protein.

Authors:  S Kurashige; M Bissett; L Oshiro
Journal:  J Clin Microbiol       Date:  1990-06       Impact factor: 5.948

4.  The use of polyvinylidenedifluoride membranes as a general blotting matrix.

Authors:  H Gültekin; K H Heermann
Journal:  Anal Biochem       Date:  1988-08-01       Impact factor: 3.365

5.  Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples.

Authors:  J B Olmsted
Journal:  J Biol Chem       Date:  1981-12-10       Impact factor: 5.157

6.  Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii.

Authors:  R H Plasterk; M I Simon; A G Barbour
Journal:  Nature       Date:  1985 Nov 21-27       Impact factor: 49.962

7.  Biochemical and immunological characterization of the surface proteins of Borrelia burgdorferi.

Authors:  B J Luft; W Jiang; P Munoz; R J Dattwyler; P D Gorevic
Journal:  Infect Immun       Date:  1989-11       Impact factor: 3.441

Review 8.  Lyme disease.

Authors:  A C Steere
Journal:  N Engl J Med       Date:  1989-08-31       Impact factor: 91.245

9.  Reinfection in erythema migrans disease.

Authors:  K Weber; G Schierz; B Wilske; U Neubert; H E Krampitz; A G Barbour; W Burgdorfer
Journal:  Infection       Date:  1986 Jan-Feb       Impact factor: 3.553

10.  European Borrelia burgdorferi isolated from humans and ticks culture conditions and antibiotic susceptibility.

Authors:  V Preac-Mursic; B Wilske; G Schierz
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1986-12
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  15 in total

1.  Reinfection in Lyme borreliosis.

Authors:  H Eiffert; F Hanefeld; R Thomssen; H J Christen
Journal:  Infection       Date:  1996 Nov-Dec       Impact factor: 3.553

2.  Evaluation of the polymerase chain reaction for the detection of Borrelia burgdorferi in cerebrospinal fluid of children with acute peripheral facial palsy.

Authors:  H J Christen; H Eiffert; A Ohlenbusch; F Hanefeld
Journal:  Eur J Pediatr       Date:  1995-05       Impact factor: 3.183

3.  The 39-kilodalton protein of Borrelia burgdorferi: a target for bactericidal human monoclonal antibodies.

Authors:  M Scriba; J S Ebrahim; T Schlott; H Eiffert
Journal:  Infect Immun       Date:  1993-10       Impact factor: 3.441

4.  Characterization of Finnish Borrelia burgdorferi sensu lato isolates by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and with monoclonal antibodies.

Authors:  J Tuomi; L K Rantamäki; R Tanskanen; J Junttila
Journal:  J Clin Microbiol       Date:  1995-08       Impact factor: 5.948

5.  An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis.

Authors:  B Wilske; V Preac-Mursic; U B Göbel; B Graf; S Jauris; E Soutschek; E Schwab; G Zumstein
Journal:  J Clin Microbiol       Date:  1993-02       Impact factor: 5.948

6.  Regulation of expression of major outer surface proteins in Borrelia burgdorferi.

Authors:  N Margolis; P A Rosa
Journal:  Infect Immun       Date:  1993-05       Impact factor: 3.441

7.  Identification of a protein in several Borrelia species which is related to OspC of the Lyme disease spirochetes.

Authors:  R T Marconi; D S Samuels; T G Schwan; C F Garon
Journal:  J Clin Microbiol       Date:  1993-10       Impact factor: 5.948

8.  Molecular analysis of the outer surface protein A (OspA) of Borrelia burgdorferi for conserved and variable antibody binding domains.

Authors:  B Wilske; B Luft; W H Schubach; G Zumstein; S Jauris; V Preac-Mursic; M D Kramer
Journal:  Med Microbiol Immunol       Date:  1992       Impact factor: 3.402

9.  Analysis of the distribution and molecular heterogeneity of the ospD gene among the Lyme disease spirochetes: evidence for lateral gene exchange.

Authors:  R T Marconi; D S Samuels; R K Landry; C F Garon
Journal:  J Bacteriol       Date:  1994-08       Impact factor: 3.490

10.  Identification of a highly cross-reactive outer surface protein B epitope among diverse geographic isolates of Borrelia spp. causing Lyme disease.

Authors:  R J Shoberg; M Jonsson; A Sadziene; S Bergström; D D Thomas
Journal:  J Clin Microbiol       Date:  1994-02       Impact factor: 5.948
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