Literature DB >> 8478112

Regulation of expression of major outer surface proteins in Borrelia burgdorferi.

N Margolis1, P A Rosa.   

Abstract

We have characterized a Borrelia burgdorferi clone (CA-11 2A) that does not synthesize the major outer surface proteins, OspA and OspB. While the osp operon is intact and capable of expression, no mRNA transcript is detectable in this clone. These results suggest that osp operon expression in the B. burgdorferi clone can be regulated at the level of transcription.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8478112      PMCID： PMC280824          DOI： 10.1128/iai.61.5.2207-2210.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  30 in total

1.  Heterogeneity of major proteins in Lyme disease borreliae: a molecular analysis of North American and European isolates.

Authors:  A G Barbour; R A Heiland; T R Howe
Journal:  J Infect Dis       Date:  1985-09       Impact factor: 5.226

2.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

3.  The analysis of nucleic acids in gels using glyoxal and acridine orange.

Authors:  G G Carmichael; G K McMaster
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

4.  Lyme disease spirochetes and ixodid tick spirochetes share a common surface antigenic determinant defined by a monoclonal antibody.

Authors:  A G Barbour; S L Tessier; W J Todd
Journal:  Infect Immun       Date:  1983-08       Impact factor: 3.441

5.  Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing.

Authors:  J R Nevins; M C Wilson
Journal:  Nature       Date:  1981-03-12       Impact factor: 49.962

6.  Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit.

Authors:  T R Howe; F W LaQuier; A G Barbour
Journal:  Infect Immun       Date:  1986-10       Impact factor: 3.441

7.  Monoclonal antibody against a genus-specific antigen of Chlamydia species: location of the epitope on chlamydial lipopolysaccharide.

Authors:  H D Caldwell; P J Hitchcock
Journal:  Infect Immun       Date:  1984-05       Impact factor: 3.441

8.  Recombination between genes encoding major outer surface proteins A and B of Borrelia burgdorferi.

Authors:  P A Rosa; T Schwan; D Hogan
Journal:  Mol Microbiol       Date:  1992-10       Impact factor: 3.501

9.  A single recombinant plasmid expressing two major outer surface proteins of the Lyme disease spirochete.

Authors:  T R Howe; L W Mayer; A G Barbour
Journal:  Science       Date:  1985-02-08       Impact factor: 47.728

10.  Isolation and cultivation of Lyme disease spirochetes.

Authors:  A G Barbour
Journal:  Yale J Biol Med       Date:  1984 Jul-Aug
View more
  31 in total

1.  Proteins binding to the promoter region of the operon encoding the major outer surface proteins OspA and OspB of Borrelia burgdorferi.

Authors:  N Margolis; D S Samuels
Journal:  Mol Biol Rep       Date:  1995       Impact factor: 2.316

2.  Analysis of the ospC regulatory element controlled by the RpoN-RpoS regulatory pathway in Borrelia burgdorferi.

Authors:  Xiaofeng F Yang; Meghan C Lybecker; Utpal Pal; Sophie M Alani; Jon Blevins; Andrew T Revel; D Scott Samuels; Michael V Norgard
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

3.  Plasmid location of Borrelia purine biosynthesis gene homologs.

Authors:  N Margolis; D Hogan; K Tilly; P A Rosa
Journal:  J Bacteriol       Date:  1994-11       Impact factor: 3.490

4.  Differential immune responses to Borrelia burgdorferi in European wild rodent species influence spirochete transmission to Ixodes ricinus L. (Acari: Ixodidae).

Authors:  K Kurtenbach; A Dizij; H M Seitz; G Margos; S E Moter; M D Kramer; R Wallich; U E Schaible; M M Simon
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

5.  gyrB mutations in coumermycin A1-resistant Borrelia burgdorferi.

Authors:  D S Samuels; R T Marconi; W M Huang; C F Garon
Journal:  J Bacteriol       Date:  1994-05       Impact factor: 3.490

6.  Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo.

Authors:  R Wallich; C Brenner; M D Kramer; M M Simon
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441

7.  Induction of an outer surface protein on Borrelia burgdorferi during tick feeding.

Authors:  T G Schwan; J Piesman; W T Golde; M C Dolan; P A Rosa
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205

8.  Molecular and evolutionary analyses of a variable series of genes in Borrelia burgdorferi that are related to ospE and ospF, constitute a gene family, and share a common upstream homology box.

Authors:  R T Marconi; S Y Sung; C A Hughes; J A Carlyon
Journal:  J Bacteriol       Date:  1996-10       Impact factor: 3.490

9.  Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen.

Authors:  W S Probert; R B LeFebvre
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

10.  Interaction of Borrelia burgdorferi Hbb with the p66 promoter.

Authors:  Melisa S Medrano; Paul F Policastro; Tom G Schwan; Jenifer Coburn
Journal:  Nucleic Acids Res       Date:  2009-11-12       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.