Literature DB >> 15581959

A fertility-sparing alternative to radical hysterectomy: how many patients may be eligible?

Yukio Sonoda1, Nadeem R Abu-Rustum, Mary L Gemignani, Dennis S Chi, Carol L Brown, Elizabeth A Poynor, Richard R Barakat.   

Abstract

OBJECTIVE: To determine the percentage of patients with early-stage cervical cancer who may be eligible for fertility preservation with laparoscopic radical vaginal trachelectomy (LRVT).
METHODS: We retrospectively reviewed the records of patients who underwent a radical hysterectomy for invasive cervical cancer at our institution from 12/85 to 8/01, before our use of LRVT at Memorial Sloan-Kettering Cancer Center. Institutional eligibility criteria for LRVT were applied. Patients > or =40 years of age were considered ineligible.
RESULTS: We identified 435 patients who had undergone radical hysterectomy for cervical cancer; 186 were age < 40 at surgery and constituted our study population. Eighty-nine (48%) patients may have been eligible by our pathologic criteria. In 12 patients, LRVT may have been aborted or altered because of unexpected disease spread.
CONCLUSION: A significant number of patients < 40 with early-stage cervical cancer may be pathologically eligible for LRVT and should be counseled on this preoperatively.

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Year:  2004        PMID: 15581959     DOI: 10.1016/j.ygyno.2004.07.060

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  21 in total

Review 1.  Diagnosis and management of cervical cancer.

Authors:  Patrick Petignat; Michel Roy
Journal:  BMJ       Date:  2007-10-13

Review 2.  Fertility-sparing for young patients with gynecologic cancer: How MRI can guide patient selection prior to conservative management.

Authors:  Sinead H McEvoy; Stephanie Nougaret; Nadeem R Abu-Rustum; Hebert Alberto Vargas; Elizabeth A Sadowski; Christine O Menias; Fuki Shitano; Shinya Fujii; Ramon E Sosa; Joanna G Escalon; Evis Sala; Yulia Lakhman
Journal:  Abdom Radiol (NY)       Date:  2017-10

Review 3.  Contemporary quality of life issues affecting gynecologic cancer survivors.

Authors:  Jeanne Carter; Richard Penson; Richard Barakat; Lari Wenzel
Journal:  Hematol Oncol Clin North Am       Date:  2011-12-16       Impact factor: 3.722

4.  Cervical conization and sentinel lymph node mapping in the treatment of stage I cervical cancer: is less enough?

Authors:  Vaagn Andikyan; Fady Khoury-Collado; John Denesopolis; Kay J Park; Yaser R Hussein; Carol L Brown; Yukio Sonoda; Dennis S Chi; Richard R Barakat; Nadeem R Abu-Rustum
Journal:  Int J Gynecol Cancer       Date:  2014-01       Impact factor: 3.437

5.  A 2-year prospective study assessing the emotional, sexual, and quality of life concerns of women undergoing radical trachelectomy versus radical hysterectomy for treatment of early-stage cervical cancer.

Authors:  Jeanne Carter; Yukio Sonoda; Raymond E Baser; Leigh Raviv; Dennis S Chi; Richard R Barakat; Alexia Iasonos; Carol L Brown; Nadeem R Abu-Rustum
Journal:  Gynecol Oncol       Date:  2010-11       Impact factor: 5.482

Review 6.  Early cervical neoplasia: advances in screening and treatment modalities.

Authors:  Brent Tierney; Shannon N Westin; Matthew P Schlumbrecht; Pedro T Ramirez
Journal:  Clin Adv Hematol Oncol       Date:  2010-08

7.  Conservative surgery in early-stage cervical cancer: what percentage of patients may be eligible for conization and lymphadenectomy?

Authors:  Ashlee L Smith; Michael Frumovitz; Kathleen M Schmeler; Ricardo dos Reis; Alpa M Nick; Robert L Coleman; Pedro T Ramirez
Journal:  Gynecol Oncol       Date:  2010-08-12       Impact factor: 5.482

Review 8.  Radical Trachelectomy for Early Stage Cervical Cancer.

Authors:  Anthony Costales; Chad Michener; Pedro F Escobar-Rodriguez
Journal:  Curr Treat Options Oncol       Date:  2018-11-19

9.  Fertility preservation for cancer patients: a review.

Authors:  Tosin Ajala; Junaid Rafi; Peter Larsen-Disney; Richard Howell
Journal:  Obstet Gynecol Int       Date:  2010-03-31

Review 10.  Conservative Surgery for Early Cervical Cancer.

Authors:  P Rema; Iqbal Ahmed
Journal:  Indian J Surg Oncol       Date:  2015-10-21
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