Literature DB >> 30450531

Radical Trachelectomy for Early Stage Cervical Cancer.

Anthony Costales1, Chad Michener2, Pedro F Escobar-Rodriguez3.   

Abstract

OPINION STATEMENT: In patients with early-stage cervical cancer, radical hysterectomy and pelvic lymphadenectomy is the gold standard. However, this disease commonly affects women of childbearing age; thus an option to spare fertility is ideal. This option came to fruition in the early 90s when the Dargent procedure or radical trachelectomy was first reported. The procedure has subsequently been modified as technology has improved and now may be performed via minimally invasive techniques. Additionally, with the advent of the sentinel lymph node procedure, the morbidity in this usually young patient population has continued to improve. There is a multitude of data to show that oncologic outcomes, concerning recurrence and mortality, are comparable to radical hysterectomy, as well as obstetrical outcomes are favorable. Data to support its acceptance within the gynecologic oncology community has led to radical trachelectomy being implemented into governing body guidelines and should be offered to appropriate candidates with early-stage cervical cancer who wish to preserve fertility.

Entities:  

Keywords:  Early stage cervical cancer; Fertility sparing; Radical trachelectomy

Mesh:

Year:  2018        PMID: 30450531     DOI: 10.1007/s11864-018-0591-4

Source DB:  PubMed          Journal:  Curr Treat Options Oncol        ISSN: 1534-6277


  46 in total

1.  Abdominal radical trachelectomy: a fertility-preserving option for women with early cervical cancer.

Authors:  László Ungár; László Pálfalvi; Russell Hogg; Pál Siklós; Deborah C M Boyle; Giuseppe Del Priore; J Richard Smith
Journal:  BJOG       Date:  2005-03       Impact factor: 6.531

2.  Is MRI helpful in assessing the distance of the tumour from the internal os in patients with cervical cancer below FIGO Stage IB2?

Authors:  P R Bhosale; R B Iyer; P Ramalingam; K M Schmeler; W Wei; R L Bassett; P T Ramirez; M Frumovitz
Journal:  Clin Radiol       Date:  2016-03-21       Impact factor: 2.350

3.  Successful delivery after transabdominal cerclage of uterine cervix for cervical incompetence after radical trachelectomy.

Authors:  Shinichi Ishioka; Toshiaki Endo; Tsuyoshi Baba; Yushi Akashi; Miyuki Morishita; Asuka Sugio; Naohiro Kanayama; Tsuyoshi Saito
Journal:  J Obstet Gynaecol Res       Date:  2015-05-05       Impact factor: 1.730

Review 4.  Radical trachelectomy versus radical hysterectomy for the treatment of early cervical cancer: a systematic review.

Authors:  Li Xu; Fu-Qing Sun; Zan-Hong Wang
Journal:  Acta Obstet Gynecol Scand       Date:  2011-08-26       Impact factor: 3.636

5.  Radical trachelectomy in early-stage cervical cancer: A comparison of laparotomy and minimally invasive surgery.

Authors:  Marcelo A Vieira; Gabriel J Rendón; Mark Munsell; Lina Echeverri; Michael Frumovitz; Kathleen M Schmeler; Rene Pareja; Pedro F Escobar; Ricardo Dos Reis; Pedro T Ramirez
Journal:  Gynecol Oncol       Date:  2015-06-18       Impact factor: 5.482

6.  A fertility-sparing alternative to radical hysterectomy: how many patients may be eligible?

Authors:  Yukio Sonoda; Nadeem R Abu-Rustum; Mary L Gemignani; Dennis S Chi; Carol L Brown; Elizabeth A Poynor; Richard R Barakat
Journal:  Gynecol Oncol       Date:  2004-12       Impact factor: 5.482

7.  Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer.

Authors:  Kota Umemura; Shin-ichi Ishioka; Toshiaki Endo; Tsuyoshi Baba; Yoshiaki Ezaka; Kunihiko Nagasawa; Madoka Takahashi; Masahito Mizuuchi; Nanako Iwami; Hidefumi Adachi; Noriko Takeda; Mitsuharu Tamagawa; Tsuyoshi Saito
Journal:  Int J Med Sci       Date:  2010-08-05       Impact factor: 3.738

Review 8.  Surgical, oncological, and obstetrical outcomes after abdominal radical trachelectomy - a systematic literature review.

Authors:  René Pareja; Gabriel J Rendón; Carlos Millán Sanz-Lomana; Otto Monzón; Pedro T Ramirez
Journal:  Gynecol Oncol       Date:  2013-06-14       Impact factor: 5.482

9.  Oncologic outcome of fertility-sparing radical trachelectomy versus radical hysterectomy for stage IB1 cervical carcinoma.

Authors:  John P Diaz; Yukio Sonoda; Mario M Leitao; Oliver Zivanovic; Carol L Brown; Dennis S Chi; Richard R Barakat; Nadeem R Abu-Rustum
Journal:  Gynecol Oncol       Date:  2008-08-27       Impact factor: 5.482

Review 10.  First case of a centropelvic recurrence after radical trachelectomy: literature review and implications for the preoperative selection of patients.

Authors:  Philippe Morice; Daniel Dargent; Christine Haie-Meder; Pierre Duvillard; Damienne Castaigne
Journal:  Gynecol Oncol       Date:  2004-03       Impact factor: 5.482

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  5 in total

Review 1.  Fertility-Sparing and Less Radical Surgery for Cervical Cancer.

Authors:  Samantha H Batman; Kathleen M Schmeler
Journal:  Curr Oncol Rep       Date:  2022-08-12       Impact factor: 5.945

2.  Minimally invasive versus open radical trachelectomy for early-stage cervical cancer: protocol for a multicenter randomized controlled trial in China.

Authors:  Xiaopei Chao; Lei Li; Ming Wu; Huanwen Wu; Shuiqing Ma; Xianjie Tan; Sen Zhong; Jinghe Lang
Journal:  Trials       Date:  2020-12-14       Impact factor: 2.279

3.  The best postoperative adjuvant therapy for patients with early stage cervical adenosquamous carcinoma.

Authors:  Yawen Liu; Haiyan Tu; Lingling Zhang; Meiling Zhong; Yanan Wang; Ling Li; Xiaojun Xiang
Journal:  BMC Womens Health       Date:  2022-04-12       Impact factor: 2.809

Review 4.  Gynecological cancer among adolescents and young adults (AYA).

Authors:  Silvia Triarico; Michele Antonio Capozza; Stefano Mastrangelo; Giorgio Attinà; Palma Maurizi; Antonio Ruggiero
Journal:  Ann Transl Med       Date:  2020-03

5.  Outcome and Subsequent Pregnancy after Fertility-Sparing Surgery of Early-Stage Cervical Cancers.

Authors:  Chia-Yi Lee; Yu-Li Chen; Ying-Cheng Chiang; Ching-Yu Cheng; Yen-Ling Lai; Yi-Jou Tai; Heng-Cheng Hsu; Hsiao-Lin Hwa; Wen-Fang Cheng
Journal:  Int J Environ Res Public Health       Date:  2020-09-28       Impact factor: 3.390

  5 in total

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