Literature DB >> 27651696

Conservative Surgery for Early Cervical Cancer.

P Rema1, Iqbal Ahmed1.   

Abstract

There is a rising incidence of early cervical cancer in young patients as a result of screening and early detection. Treatment of cervical cancer by surgery or radiotherapy results in permanent infertility which affects the quality of life of cancer survivors. Now with improved survival rates among early cervical cancer patients, conservative surgery aiming at fertility preservation in those desiring future pregnancy is an accepted treatment. Conservative surgery is possible in early cervical cancer including micro invasive cancer and stage IB cancers less than 2 cm. Stage IA1 cervical cancer is treated effectively by cervical conisation. In stage IA2 cancers and stage IB1 cancers less than 2 cm the fertility preservation surgery is radical trachelectomy. Radical trachelectomy removes the cervix with medial parametrium and upper 2 cm vaginal cuff retaining the uterus and adnexa to allow future pregnancy. Radical trachelectomy is a safe procedure in selected patients with cancer cervix with acceptable oncologic risks and promising obstetric outcome. It should be avoided in tumours larger than 2 cm and aggressive histologic types. This article focuses on the current options of conservative surgery in early cervical cancer.

Entities:  

Keywords:  Cancer cervix; Conservative surgery; Fertility preservation; Radical trachelectomy

Year:  2015        PMID: 27651696      PMCID: PMC5016325          DOI: 10.1007/s13193-015-0476-y

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  25 in total

1.  Radical trachelectomy in early stage carcinoma of the cervix: outcome as judged by recurrence and fertility rates.

Authors:  J H Shepherd; T Mould; D H Oram
Journal:  BJOG       Date:  2001-08       Impact factor: 6.531

2.  Conservation of ovarian tissue in the treatment of carcinoma of the cervix with radical surgery.

Authors:  M L McCALL; E C KEATY; J D THOMPSON
Journal:  Am J Obstet Gynecol       Date:  1958-03       Impact factor: 8.661

3.  Fertility-conserving surgery for young women with stage IA1 cervical cancer: safety and access.

Authors:  Jason D Wright; Ruvandhi Nathavithrana; Sharyn N Lewin; Xuming Sun; Israel Deutsch; William M Burke; Thomas J Herzog
Journal:  Obstet Gynecol       Date:  2010-03       Impact factor: 7.661

4.  Radical vaginal trachelectomy as a fertility-sparing procedure in women with early-stage cervical cancer-cumulative pregnancy rate in a series of 123 women.

Authors:  J H Shepherd; C Spencer; J Herod; T E J Ind
Journal:  BJOG       Date:  2006-06       Impact factor: 6.531

5.  Ovarian metastases from stage IB adenocarcinoma of the cervix.

Authors:  W J Mann; J Chumas; T Amalfitano; C Westermann; B Patsner
Journal:  Cancer       Date:  1987-09-01       Impact factor: 6.860

6.  A fertility-sparing alternative to radical hysterectomy: how many patients may be eligible?

Authors:  Yukio Sonoda; Nadeem R Abu-Rustum; Mary L Gemignani; Dennis S Chi; Carol L Brown; Elizabeth A Poynor; Richard R Barakat
Journal:  Gynecol Oncol       Date:  2004-12       Impact factor: 5.482

Review 7.  Surgical, oncological, and obstetrical outcomes after abdominal radical trachelectomy - a systematic literature review.

Authors:  René Pareja; Gabriel J Rendón; Carlos Millán Sanz-Lomana; Otto Monzón; Pedro T Ramirez
Journal:  Gynecol Oncol       Date:  2013-06-14       Impact factor: 5.482

8.  Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.

Authors:  Jacques Ferlay; Isabelle Soerjomataram; Rajesh Dikshit; Sultan Eser; Colin Mathers; Marise Rebelo; Donald Maxwell Parkin; David Forman; Freddie Bray
Journal:  Int J Cancer       Date:  2014-10-09       Impact factor: 7.396

9.  Trends in breast, ovarian and cervical cancer incidence in Mumbai, India over a 30-year period, 1976-2005: an age-period-cohort analysis.

Authors:  P K Dhillon; B B Yeole; R Dikshit; A P Kurkure; F Bray
Journal:  Br J Cancer       Date:  2011-08-09       Impact factor: 7.640

10.  Fertility-sparing surgery for early-stage cervical cancer.

Authors:  Adelaide Fernanda Ribeiro Cubal; Joana Isabel Ferreira Carvalho; Maria Fernanda Martins Costa; Ana Paula Tavares Branco
Journal:  Int J Surg Oncol       Date:  2012-07-08
View more
  2 in total

Review 1.  Electrical stimulation on adverse events caused by chemotherapy in patients with cervical cancer: A protocol for a systematic review of randomized controlled trial.

Authors:  Peng-Hui Dou; Dan-Feng Zhang; Cui-Hong Su; Xiao-Li Zhang; Ying-Jie Wu
Journal:  Medicine (Baltimore)       Date:  2019-02       Impact factor: 1.817

2.  Are patients and physicians willing to accept less-radical procedures for cervical cancer?

Authors:  Kemal Gungorduk; Roman Kocian; Derman Basaran; Taner Turan; Aykut Ozdemir; David Cibula
Journal:  J Gynecol Oncol       Date:  2018-03-12       Impact factor: 4.401

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.