Literature DB >> 15565251

Chemical aspects of amine oxidation by flavoprotein enzymes.

Nigel S Scrutton1.   

Abstract

The mechanism of amine oxidation by flavoprotein enzymes is critically analysed through analysis of available experimental data. The review assesses available evidence for radical and polar mechanisms, drawing on data from model reactions, kinetic and spectroscopic approaches, structural and mutagenesis studies. The review focused on studies of mammalian monoamine oxidases and the bacterial enzymes trimethylamine dehydrogenase, monomeric sarcosine oxidase and dimethylglycine oxidase.

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Year:  2004        PMID： 15565251     DOI： 10.1039/b306788m

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  24 in total

Review 1.  Monoamine oxidases in development.

Authors:  Chi Chiu Wang; Ellen Billett; Astrid Borchert; Hartmut Kuhn; Christoph Ufer
Journal:  Cell Mol Life Sci       Date:  2012-07-11       Impact factor: 9.261

Review 2.  Evolution of catabolic pathways: Genomic insights into microbial s-triazine metabolism.

Authors:  N Shapir; E F Mongodin; M J Sadowsky; S C Daugherty; K E Nelson; L P Wackett
Journal:  J Bacteriol       Date:  2006-11-17       Impact factor: 3.490

3.  Insights into the mechanism of flavoprotein-catalyzed amine oxidation from nitrogen isotope effects on the reaction of N-methyltryptophan oxidase.

Authors:  Erik C Ralph; Jennifer S Hirschi; Mark A Anderson; W Wallace Cleland; Daniel A Singleton; Paul F Fitzpatrick
Journal:  Biochemistry       Date:  2007-06-02       Impact factor: 3.162

4.  An internal reaction chamber in dimethylglycine oxidase provides efficient protection from exposure to toxic formaldehyde.

Authors:  Tewes Tralau; Pierre Lafite; Colin Levy; John P Combe; Nigel S Scrutton; David Leys
Journal:  J Biol Chem       Date:  2009-04-15       Impact factor: 5.157

5.  Mechanistic studies of the flavoenzyme tryptophan 2-monooxygenase: deuterium and 15N kinetic isotope effects on alanine oxidation by an L-amino acid oxidase.

Authors:  Erik C Ralph; Mark A Anderson; W Wallace Cleland; Paul F Fitzpatrick
Journal:  Biochemistry       Date:  2006-12-26       Impact factor: 3.162

6.  Computational investigation on the structure-activity relationship of the biradical mechanism for monoamine oxidase.

Authors:  Safiye S Erdem; Burcu Büyükmenekşe
Journal:  J Neural Transm (Vienna)       Date:  2011-04-08       Impact factor: 3.575

7.  pH and deuterium isotope effects on the reaction of trimethylamine dehydrogenase with dimethylamine.

Authors:  Udayanga S Wanninayake; Bishnu Subedi; Paul F Fitzpatrick
Journal:  Arch Biochem Biophys       Date:  2019-10-08       Impact factor: 4.013

8.  Regulation of monoamine oxidase A (MAO-A) expression, activity, and function in IL-13-stimulated monocytes and A549 lung carcinoma cells.

Authors:  Sukhamoy Dhabal; Pradip Das; Pritam Biswas; Priyanka Kumari; Valentin P Yakubenko; Suman Kundu; Martha K Cathcart; Manjari Kundu; Kaushik Biswas; Ashish Bhattacharjee
Journal:  J Biol Chem       Date:  2018-07-18       Impact factor: 5.157

9.  Serotonin produces monoamine oxidase-dependent oxidative stress in human heart valves.

Authors:  Ricardo A Peña-Silva; Jordan D Miller; Yi Chu; Donald D Heistad
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-08-07       Impact factor: 4.733

10.  Mechanistic studies of human spermine oxidase: kinetic mechanism and pH effects.

Authors:  Mariya S Adachi; Paul R Juarez; Paul F Fitzpatrick
Journal:  Biochemistry       Date:  2010-01-19       Impact factor: 3.162
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