Literature DB >> 15548122

Comparisons of LET distributions for protons with energies between 50 and 200 MeV determined using a spherical tissue-equivalent proportional counter (TEPC) and a position-sensitive silicon spectrometer (RRMD-III).

T B Borak1, T Doke, T Fuse, S Guetersloh, L Heilbronn, K Hara, M Moyers, S Suzuki, P Taddei, K Terasawa, C J Zeitlin.   

Abstract

Experiments have been performed to measure the response of a spherical tissue-equivalent proportional counter (TEPC) and a silicon-based LET spectrometer (RRMD-III) to protons with energies ranging from 50-200 MeV. This represents a large portion of the energy distribution for trapped protons encountered by astronauts in low-Earth orbit. The beam energies were obtained using plastic polycarbonate degraders with a monoenergetic beam that was extracted from a proton synchrotron. The LET spectrometer provided excellent agreement with the expected LET distribution emerging from the energy degraders. The TEPC cannot measure the LET distribution directly. However, the frequency mean value of lineal energy, y(-)(f), provided a good approximation to LET. This is in contrast to previous results for high-energy heavy ions where y(-)(f) underestimated LET, whereas the dose-averaged lineal energy, y(-)(D), provided a good approximation to LET.

Keywords:  NASA Discipline Radiation Health; Non-NASA Center

Mesh:

Substances:

Year:  2004        PMID: 15548122     DOI: 10.1667/rr3262

Source DB:  PubMed          Journal:  Radiat Res        ISSN: 0033-7587            Impact factor:   2.841


  6 in total

1.  The response of a spherical tissue-equivalent proportional counter to different heavy ions having similar velocities.

Authors:  Phillip J Taddei; Thomas B Borak; Stephen B Guetersloh; Brad B Gersey; Cary Zeitlin; Lawrence Heilbronn; Jack Miller; Takeshi Murakami; Yoshiyuki Iwata
Journal:  Radiat Meas       Date:  2006-10       Impact factor: 1.898

2.  The microdosimetric extension in TOPAS: development and comparison with published data.

Authors:  Hongyu Zhu; Yizheng Chen; Wonmo Sung; Aimee L McNamara; Linh T Tran; Lucas N Burigo; Anatoly B Rosenfeld; Junli Li; Bruce Faddegon; Jan Schuemann; Harald Paganetti
Journal:  Phys Med Biol       Date:  2019-07-11       Impact factor: 3.609

3.  The influence of Geant4-DNA toolkit parameters on electron microdosimetric track structure.

Authors:  Yidi Wang; Zhanpeng Li; Shuyuan Zhang; Wei Tang; Xiang Li; Dandan Chen; Liang Sun
Journal:  J Radiat Res       Date:  2020-01-23       Impact factor: 2.724

4.  A comparison of the measured responses of a tissue-equivalent proportional counter to high energy heavy (HZE) particles and those simulated using the Geant4 Monte Carlo code.

Authors:  Phillip J Taddei; Zhongxiang Zhao; Thomas B Borak
Journal:  Radiat Meas       Date:  2008-10       Impact factor: 1.898

5.  Low- and middle-income countries can reduce risks of subsequent neoplasms by referring pediatric craniospinal cases to centralized proton treatment centers.

Authors:  Phillip J Taddei; Nabil Khater; Bassem Youssef; Rebecca M Howell; Wassim Jalbout; Rui Zhang; Fady B Geara; Annelise Giebeler; Anita Mahajan; Dragan Mirkovic; Wayne D Newhauser
Journal:  Biomed Phys Eng Express       Date:  2018-02-07

6.  Dual-storage phosphor proton therapy dosimetry: Simultaneous quantification of dose and linear energy transfer.

Authors:  Jufri Setianegara; Thomas R Mazur; Deshan Yang; H Harold Li
Journal:  Med Phys       Date:  2021-02-19       Impact factor: 4.071

  6 in total

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