Literature DB >> 15337105

Systems approaches to understanding cell signaling and gene regulation.

Nicholas J Provart1, Peter McCourt.   

Abstract

The age of 'omics' is upon us, and scientific papers that reflect this are starting to appear at an ever-increasing rate. The amount of information generated in any 'omics' program is daunting and often overwhelms plant scientists whose main interests relate to cell or developmental biology. For this revolution in data generation to have any impact in plant signaling studies, we must have great confidence in both the quality of the data and our ability to represent it in ways that are meaningful to general plant biologists. Systems biology has begun to address these issues and to provide examples in which the analysis of large data sets has led to biological insights into cell signaling and gene regulation.

Mesh:

Year:  2004        PMID: 15337105     DOI: 10.1016/j.pbi.2004.07.001

Source DB:  PubMed          Journal:  Curr Opin Plant Biol        ISSN: 1369-5266            Impact factor:   7.834


  8 in total

Review 1.  High-throughput RNA isolation technologies. New tools for high-resolution gene expression profiling in plant systems.

Authors:  Ji-Young Lee; Mitchell Levesque; Philip N Benfey
Journal:  Plant Physiol       Date:  2005-06       Impact factor: 8.340

2.  Unifying measures of gene function and evolution.

Authors:  Yuri I Wolf; Liran Carmel; Eugene V Koonin
Journal:  Proc Biol Sci       Date:  2006-06-22       Impact factor: 5.349

3.  Abiotic stress in rice. An "omic" approach.

Authors:  Aleel K Grennan
Journal:  Plant Physiol       Date:  2006-04       Impact factor: 8.340

Review 4.  A survey of yeast genomic assays for drug and target discovery.

Authors:  Andrew M Smith; Ron Ammar; Corey Nislow; Guri Giaever
Journal:  Pharmacol Ther       Date:  2010-05-28       Impact factor: 12.310

Review 5.  Arabidopsis thaliana as a model organism in systems biology.

Authors:  Jaimie M Van Norman; Philip N Benfey
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2009 Nov-Dec

Review 6.  Applying a systems approach to thyroid physiology: Looking at the whole with a mitochondrial perspective instead of judging single TSH values or why we should know more about mitochondria to understand metabolism.

Authors:  Roy Moncayo; Helga Moncayo
Journal:  BBA Clin       Date:  2017-04-04

7.  Developing a systems biology approach to study disease progression caused by Heterodera glycines in Glycine max.

Authors:  Vincent P Klink; Christopher C Overall; Benjamin F Matthews
Journal:  Gene Regul Syst Bio       Date:  2007-06-05

8.  Data mining for gene networks relevant to poor prognosis in lung cancer via backward-chaining rule induction.

Authors:  Mary E Edgerton; Douglas H Fisher; Lianhong Tang; Lewis J Frey; Zhihua Chen
Journal:  Cancer Inform       Date:  2007-02-10
  8 in total

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