Literature DB >> 1528874

Ribosomal movement impeded at a pseudoknot required for frameshifting.

C Tu1, T H Tzeng, J A Bruenn.   

Abstract

Translational frameshifting sometimes occurs when ribosomes encounter a "shift" site preceding a region of unusual secondary structure, which in at least three cases is known to be a pseudoknot. We provide evidence that ribosomes have a decreased rate of movement through a pseudoknot required for frameshifting. These paused ribosomes are directly situated over the shift sequence. Ribosomal pausing appears to be necessary but not sufficient for frameshifting.

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Substances：

Year:  1992        PMID： 1528874      PMCID： PMC49975          DOI： 10.1073/pnas.89.18.8636

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  Biosynthesis of reovirus-specified polypeptides: ribosome pausing during the translation of reovirus S1 mRNA.

Authors:  J P Doohan; C E Samuel
Journal:  Virology       Date:  1992-02       Impact factor: 3.616

2.  Translational frameshifting: where will it stop?

Authors:  W J Craigen; C T Caskey
Journal:  Cell       Date:  1987-07-03       Impact factor: 41.582

3.  Production of single-stranded plasmid DNA.

Authors:  J Vieira; J Messing
Journal:  Methods Enzymol       Date:  1987       Impact factor: 1.600

4.  Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter.

Authors:  D A Melton; P A Krieg; M R Rebagliati; T Maniatis; K Zinn; M R Green
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

5.  Rapid RNA sequencing: nucleases from Staphylococcus aureus and Neurospora crassa discriminate between uridine and cytidine.

Authors:  G Krupp; H J Gross
Journal:  Nucleic Acids Res       Date:  1979-08-10       Impact factor: 16.971

6.  A -1 ribosomal frameshift in a double-stranded RNA virus of yeast forms a gag-pol fusion protein.

Authors:  J D Dinman; T Icho; R B Wickner
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

7.  Ribosomal frameshifting requires a pseudoknot in the Saccharomyces cerevisiae double-stranded RNA virus.

Authors:  T H Tzeng; C L Tu; J A Bruenn
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

8.  An RNA pseudoknot and an optimal heptameric shift site are required for highly efficient ribosomal frameshifting on a retroviral messenger RNA.

Authors:  M Chamorro; N Parkin; H E Varmus
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-15       Impact factor: 11.205

9.  Mutational analysis of the RNA pseudoknot component of a coronavirus ribosomal frameshifting signal.

Authors:  I Brierley; N J Rolley; A J Jenner; S C Inglis
Journal:  J Mol Biol       Date:  1991-08-20       Impact factor: 5.469

10.  Ribosomal frameshifting in the yeast retrotransposon Ty: tRNAs induce slippage on a 7 nucleotide minimal site.

Authors:  M F Belcourt; P J Farabaugh
Journal:  Cell       Date:  1990-07-27       Impact factor: 41.582
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  102 in total

1.  Programmed ribosomal frameshifting: much ado about knotting!

Authors:  S L Alam; J F Atkins; R F Gesteland
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

2.  Specific mutations in a viral RNA pseudoknot drastically change ribosomal frameshifting efficiency.

Authors:  Y G Kim; L Su; S Maas; A O'Neill; A Rich
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

3.  Kinetics of ribosomal pausing during programmed -1 translational frameshifting.

Authors:  J D Lopinski; J D Dinman; J A Bruenn
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272

4.  Programmed +1 frameshifting stimulated by complementarity between a downstream mRNA sequence and an error-correcting region of rRNA.

Authors:  Z Li; G Stahl; P J Farabaugh
Journal:  RNA       Date:  2001-02       Impact factor: 4.942

5.  The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure.

Authors:  Jonathan D Dinman; Sara Richter; Ewan P Plant; Ronald C Taylor; Amy B Hammell; Tariq M Rana
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

Review 6.  The 9-A solution: how mRNA pseudoknots promote efficient programmed -1 ribosomal frameshifting.

Authors:  Ewan P Plant; Kristi L Muldoon Jacobs; Jason W Harger; Arturas Meskauskas; Jonathan L Jacobs; Jennifer L Baxter; Alexey N Petrov; Jonathan D Dinman
Journal:  RNA       Date:  2003-02       Impact factor: 4.942

7.  Comparative studies of frameshifting and nonframeshifting RNA pseudoknots: a mutational and NMR investigation of pseudoknots derived from the bacteriophage T2 gene 32 mRNA and the retroviral gag-pro frameshift site.

Authors:  Yue Wang; Norma M Wills; Zhihua Du; Anupama Rangan; John F Atkins; Raymond F Gesteland; David W Hoffman
Journal:  RNA       Date:  2002-08       Impact factor: 4.942

8.  Efficiency of a programmed -1 ribosomal frameshift in the different subtypes of the human immunodeficiency virus type 1 group M.

Authors:  Martin Baril; Dominic Dulude; Karine Gendron; Guy Lemay; Léa Brakier-Gingras
Journal:  RNA       Date:  2003-10       Impact factor: 4.942

9.  Identification of a cellular factor that modulates HIV-1 programmed ribosomal frameshifting.

Authors:  Yoshifumi Kobayashi; Jianling Zhuang; Stuart Peltz; Joseph Dougherty
Journal:  J Biol Chem       Date:  2010-04-23       Impact factor: 5.157

10.  Special peptidyl-tRNA molecules can promote translational frameshifting without slippage.

Authors:  A Vimaladithan; P J Farabaugh
Journal:  Mol Cell Biol       Date:  1994-12       Impact factor: 4.272
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