Literature DB >> 15273152

Role of beta-lactamases and porins in resistance to ertapenem and other beta-lactams in Klebsiella pneumoniae.

George A Jacoby1, Debra M Mills, Nancy Chow.   

Abstract

High-level resistance to ertapenem was produced by beta-lactamases of groups 1, 2f, and 3 in a strain of Klebsiella pneumoniae deficient in Omp35 and Omp36. From a wild-type strain producing ACT-1 beta-lactamase, ertapenem-resistant mutants for which the ertapenem MICs were up to 128 microg/ml and expression of outer membrane proteins was diminished could be selected.

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Year:  2004        PMID： 15273152      PMCID： PMC478483          DOI： 10.1128/AAC.48.8.3203-3206.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  13 in total

1.  In vitro activities of ertapenem (MK-0826) against clinical bacterial isolates from 11 North American medical centers.

Authors:  P C Fuchs; A L Barry; S D Brown
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

2.  In vitro activities of ertapenem (MK-0826) against recent clinical bacteria collected in Europe and Australia.

Authors:  D M Livermore; M W Carter; S Bagel; B Wiedemann; F Baquero; E Loza; H P Endtz; N van Den Braak; C J Fernandes; L Fernandes; N Frimodt-Moller; L S Rasmussen; H Giamarellou; E Giamarellos-Bourboulis; V Jarlier; J Nguyen; C E Nord; M J Struelens; C Nonhoff; J Turnidge; J Bell; R Zbinden; S Pfister; L Mixson; D L Shungu
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

3.  Roles of beta-lactamases and porins in activities of carbapenems and cephalosporins against Klebsiella pneumoniae.

Authors:  L Martínez-Martínez; A Pascual; S Hernández-Allés; D Alvarez-Díaz; A I Suárez; J Tran; V J Benedí; G A Jacoby
Journal:  Antimicrob Agents Chemother       Date:  1999-07       Impact factor: 5.191

Review 4.  A functional classification scheme for beta-lactamases and its correlation with molecular structure.

Authors:  K Bush; G A Jacoby; A A Medeiros
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191

5.  AcrAB Efflux System: Expression and Contribution to Fluoroquinolone Resistance in Klebsiella spp.

Authors:  Annarita Mazzariol; Jessica Zuliani; Giuseppe Cornaglia; Gian Maria Rossolini; Roberta Fontana
Journal:  Antimicrob Agents Chemother       Date:  2002-12       Impact factor: 5.191

6.  Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae.

Authors:  H Yigit; A M Queenan; G J Anderson; A Domenech-Sanchez; J W Biddle; C D Steward; S Alberti; K Bush; F C Tenover
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

7.  Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.

Authors:  P A Bradford; C Urban; N Mariano; S J Projan; J J Rahal; K Bush
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

8.  In vitro activity of clinafloxacin in comparison with other quinolones against Stenotrophomonas maltophilia clinical isolates in the presence and absence of reserpine.

Authors:  Anna Ribera; Angels Jurado; Joaquim Ruiz; Francesc Marco; Oscar Del Valle; Josep Mensa; Josep Chaves; Gonzalo Hernández; M Teresa Jiménez de Anta; Jordi Vila
Journal:  Diagn Microbiol Infect Dis       Date:  2002-02       Impact factor: 2.803

9.  Detection of extended-spectrum beta-lactamases in clinical isolates of Klebsiella pneumoniae and Escherichia coli.

Authors:  G A Jacoby; P Han
Journal:  J Clin Microbiol       Date:  1996-04       Impact factor: 5.948

10.  The AcrB multidrug transporter plays a major role in high-level fluoroquinolone resistance in Salmonella enterica serovar typhimurium phage type DT204.

Authors:  Sylvie Baucheron; Hein Imberechts; Elisabeth Chaslus-Dancla; Axel Cloeckaert
Journal:  Microb Drug Resist       Date:  2002       Impact factor: 3.431
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  72 in total

1.  OXA-163-producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010.

Authors:  Mohammed O Abdelaziz; Celestino Bonura; Aurora Aleo; Ramadan A El-Domany; Teresa Fasciana; Caterina Mammina
Journal:  J Clin Microbiol       Date:  2012-04-18       Impact factor: 5.948

2.  Detection of carbapenemase producers in Enterobacteriaceae by use of a novel screening medium.

Authors:  Patrice Nordmann; Delphine Girlich; Laurent Poirel
Journal:  J Clin Microbiol       Date:  2012-02-22       Impact factor: 5.948

3.  Plasmid-mediated imipenem-hydrolyzing enzyme KPC-2 among multiple carbapenem-resistant Escherichia coli clones in Israel.

Authors:  Shiri Navon-Venezia; Inna Chmelnitsky; Azita Leavitt; Mitchell J Schwaber; David Schwartz; Yehuda Carmeli
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

4.  Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in Enterobacter cloacae.

Authors:  Dóra Szabó; Fernanda Silveira; Andrea M Hujer; Robert A Bonomo; Kristine M Hujer; Jane W Marsh; Christopher R Bethel; Yohei Doi; Kathleen Deeley; David L Paterson
Journal:  Antimicrob Agents Chemother       Date:  2006-08       Impact factor: 5.191

5.  Structural Alteration of OmpR as a Source of Ertapenem Resistance in a CTX-M-15-Producing Escherichia coli O25b:H4 Sequence Type 131 Clinical Isolate.

Authors:  Hervé Dupont; Pascaline Choinier; David Roche; Sandine Adiba; Megan Sookdeb; Catherine Branger; Erick Denamur; Hedi Mammeri
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

6.  CTX-M expression and selection of ertapenem resistance in Klebsiella pneumoniae and Escherichia coli.

Authors:  Delphine Girlich; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2008-11-24       Impact factor: 5.191

7.  Predictability of Phenotype in Relation to Common β-Lactam Resistance Mechanisms in Escherichia coli and Klebsiella pneumoniae.

Authors:  Alex Agyekum; Alicia Fajardo-Lubián; Xiaoman Ai; Andrew N Ginn; Zhiyong Zong; Xuejun Guo; John Turnidge; Sally R Partridge; Jonathan R Iredell
Journal:  J Clin Microbiol       Date:  2016-02-24       Impact factor: 5.948

8.  Protective efficacy of DNA vaccines encoding outer membrane protein A and OmpK36 of Klebsiella pneumoniae in mice.

Authors:  Prathiba Kurupati; N P Ramachandran; Chit Laa Poh
Journal:  Clin Vaccine Immunol       Date:  2010-11-03

9.  C4-alkylthiols with activity against Moraxella catarrhalis and Mycobacterium tuberculosis.

Authors:  Maya B Kostova; Carey J Myers; Tim N Beck; Balbina J Plotkin; Jacalyn M Green; Helena I M Boshoff; Clifton E Barry; Jeffrey R Deschamps; Monika I Konaklieva
Journal:  Bioorg Med Chem       Date:  2011-10-01       Impact factor: 3.641

10.  In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains.

Authors:  Naoki Kohira; Joshua West; Akinobu Ito; Tsukasa Ito-Horiyama; Rio Nakamura; Takafumi Sato; Stephen Rittenhouse; Masakatsu Tsuji; Yoshinori Yamano
Journal:  Antimicrob Agents Chemother       Date:  2015-11-16       Impact factor: 5.191
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