Literature DB >> 15213451

Backbone resonance assignments of the 45.3 kDa catalytic domain of human BACE1.

Dingjiang Liu, Yu-Sen Wang, Jennifer J Gesell, Eileen Wilson, Brian M Beyer, Daniel F Wyss.   

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Year:  2004        PMID： 15213451     DOI： 10.1023/B:JNMR.0000032509.81283.d3

Source DB:  PubMed          Journal:  J Biomol NMR        ISSN： 0925-2738            Impact factor:   2.835


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  10 in total

1.  Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.

Authors:  Y Luo; B Bolon; S Kahn; B D Bennett; S Babu-Khan; P Denis; W Fan; H Kha; J Zhang; Y Gong; L Martin; J C Louis; Q Yan; W G Richards; M Citron; R Vassar
Journal:  Nat Neurosci       Date:  2001-03       Impact factor: 24.884

2.  Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor.

Authors:  L Hong; G Koelsch; X Lin; S Wu; S Terzyan; A K Ghosh; X C Zhang; J Tang
Journal:  Science       Date:  2000-10-06       Impact factor: 47.728

3.  Four-dimensional NMR spectroscopy of a 723-residue protein: chemical shift assignments and secondary structure of malate synthase g.

Authors:  Vitali Tugarinov; Ranjith Muhandiram; Ayeda Ayed; Lewis E Kay
Journal:  J Am Chem Soc       Date:  2002-08-28       Impact factor: 15.419

Review 4.  The search for better noncholinergic treatment options for Alzheimer's disease.

Authors:  Jacobo E Mintzer
Journal:  J Clin Psychiatry       Date:  2003       Impact factor: 4.384

5.  NMR View: A computer program for the visualization and analysis of NMR data.

Authors:  B A Johnson; R A Blevins
Journal:  J Biomol NMR       Date:  1994-09       Impact factor: 2.835

6.  Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.

Authors:  M S Wolfe; W Xia; B L Ostaszewski; T S Diehl; W T Kimberly; D J Selkoe
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

7.  Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.

Authors:  R Vassar; B D Bennett; S Babu-Khan; S Kahn; E A Mendiaz; P Denis; D B Teplow; S Ross; P Amarante; R Loeloff; Y Luo; S Fisher; J Fuller; S Edenson; J Lile; M A Jarosinski; A L Biere; E Curran; T Burgess; J C Louis; F Collins; J Treanor; G Rogers; M Citron
Journal:  Science       Date:  1999-10-22       Impact factor: 47.728

8.  NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Authors:  F Delaglio; S Grzesiek; G W Vuister; G Zhu; J Pfeifer; A Bax
Journal:  J Biomol NMR       Date:  1995-11       Impact factor: 2.835

Review 9.  Beta-secretase (BACE) as a drug target for Alzheimer's disease.

Authors:  Robert Vassar
Journal:  Adv Drug Deliv Rev       Date:  2002-12-07       Impact factor: 15.470

10.  Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor.

Authors:  J D Buxbaum; K N Liu; Y Luo; J L Slack; K L Stocking; J J Peschon; R S Johnson; B J Castner; D P Cerretti; R A Black
Journal:  J Biol Chem       Date:  1998-10-23       Impact factor: 5.157
  10 in total
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1.  Advances in Nuclear Magnetic Resonance for Drug Discovery.

Authors:  Robert Powers
Journal:  Expert Opin Drug Discov       Date:  2009-10-01       Impact factor: 6.098

Review 2.  The application of FAST-NMR for the identification of novel drug discovery targets.

Authors:  Robert Powers; Kelly A Mercier; Jennifer C Copeland
Journal:  Drug Discov Today       Date:  2008-02       Impact factor: 7.851
  2 in total

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