Literature DB >> 15213210

Genetic research and health disparities.

Pamela Sankar1, Mildred K Cho, Celeste M Condit, Linda M Hunt, Barbara Koenig, Patricia Marshall, Sandra Soo-Jin Lee, Paul Spicer.   

Abstract

Alleviating health disparities in the United States is a goal with broad support. Medical research undertaken to achieve this goal typically adopts the well-established perspective that racial discrimination and poverty are the major contributors to unequal health status. However, the suggestion is increasingly made that genetic research also has a significant role to play in alleviating this problem, which likely overstates the importance of genetics as a factor in health disparities. Overemphasis on genetics as a major explanatory factor in health disparities could lead researchers to miss factors that contribute to disparities more substantially and may also reinforce racial stereotyping, which may contribute to disparities in the first place. Arguments that promote genetics research as a way to help alleviate health disparities are augmented by several factors, including research funding initiatives and the distinct demographic patterns of health disparities in the United States.

Mesh:

Year:  2004        PMID: 15213210      PMCID: PMC2271142          DOI: 10.1001/jama.291.24.2985

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  52 in total

Review 1.  Blindness in Africa: present situation and future needs.

Authors:  S Lewallen; P Courtright
Journal:  Br J Ophthalmol       Date:  2001-08       Impact factor: 4.638

Review 2.  Current concepts on the genetics of asthma.

Authors:  H Hakonarson; M Wjst
Journal:  Curr Opin Pediatr       Date:  2001-06       Impact factor: 2.856

3.  Essay reviews. [Review of: Rabinow P. Making PCR: a story of biotechnology. University of Chicago Press, 1996; and Fujimura J. Crafting science: a sociohistory of the quest for the genetics of cancer. Harvard University Press, 1996].

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Journal:  Oral Hist Rev       Date:  1999 Summer-Fall

4.  Deaths and injuries from house fires.

Authors:  G R Istre; M A McCoy; L Osborn; J J Barnard; A Bolton
Journal:  N Engl J Med       Date:  2001-06-21       Impact factor: 91.245

Review 5.  Glaucoma.

Authors:  A L Coleman
Journal:  Lancet       Date:  1999-11-20       Impact factor: 79.321

6.  Factors associated with no surgery or radiation therapy for invasive cervical cancer in Black and White women.

Authors:  R M Merrill; A V Merrill; L S Mayer
Journal:  Ethn Dis       Date:  2000 Spring-Summer       Impact factor: 1.847

7.  Use of major therapeutic procedures: are Hispanics treated differently than non-Hispanic Whites.

Authors:  R M Andrews; A Elixhauser
Journal:  Ethn Dis       Date:  2000       Impact factor: 1.847

8.  Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure.

Authors:  C W Yancy; M B Fowler; W S Colucci; E M Gilbert; M R Bristow; J N Cohn; M A Lukas; S T Young; M Packer
Journal:  N Engl J Med       Date:  2001-05-03       Impact factor: 91.245

9.  Changes in life expectancy in Russia in the mid-1990s.

Authors:  V Shkolnikov; M McKee; D A Leon
Journal:  Lancet       Date:  2001-03-24       Impact factor: 79.321

Review 10.  Osteoarthritis: new insights. Part 1: the disease and its risk factors.

Authors:  D T Felson; R C Lawrence; P A Dieppe; R Hirsch; C G Helmick; J M Jordan; R S Kington; N E Lane; M C Nevitt; Y Zhang; M Sowers; T McAlindon; T D Spector; A R Poole; S Z Yanovski; G Ateshian; L Sharma; J A Buckwalter; K D Brandt; J F Fries
Journal:  Ann Intern Med       Date:  2000-10-17       Impact factor: 25.391

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  89 in total

1.  Estimating the contribution of genetic variants to difference in incidence of disease between population groups.

Authors:  Ramal Moonesinghe; John P A Ioannidis; W Dana Flanders; Quanhe Yang; Benedict I Truman; Muin J Khoury
Journal:  Eur J Hum Genet       Date:  2012-02-15       Impact factor: 4.246

Review 2.  A critical review of racial/ethnic variables in osteoporosis and bone density research.

Authors:  M S Megyesi; L M Hunt; H Brody
Journal:  Osteoporos Int       Date:  2011-01-05       Impact factor: 4.507

3.  Stormy weather: race, gene expression, and the science of health disparities.

Authors:  Nancy Krieger
Journal:  Am J Public Health       Date:  2005-10-27       Impact factor: 9.308

Review 4.  Measurement issues in health disparities research.

Authors:  Mildred Ramírez; Marvella E Ford; Anita L Stewart; Jeanne A Teresi
Journal:  Health Serv Res       Date:  2005-10       Impact factor: 3.402

5.  BiDil: assessing a race-based pharmaceutical.

Authors:  Howard Brody; Linda M Hunt
Journal:  Ann Fam Med       Date:  2006 Nov-Dec       Impact factor: 5.166

6.  Mixed Race: Understanding Difference in the Genome Era.

Authors:  Elizabeth M Phillips; Adebola O Odunlami; Vence L Bonham
Journal:  Soc Forces       Date:  2007-12

7.  Perceptions of African-American health professionals and community members on the participation of children and pregnant women in genetic research.

Authors:  E M Ngui; T D Warner; L W Roberts
Journal:  Public Health Genomics       Date:  2013-11-06       Impact factor: 2.000

8.  Barriers and Strategies Related to Qualitative Research on Genetic Ancestry Testing in Indigenous Communities.

Authors:  Jessica W Blanchard; Gloria Tallbull; Chantelle Wolpert; Jill Powell; Morris W Foster; Charmaine Royal
Journal:  J Empir Res Hum Res Ethics       Date:  2017-04-23       Impact factor: 1.742

9.  Too many referrals of low-risk women for BRCA1/2 genetic services by family physicians.

Authors:  Della Brown White; Vence L Bonham; Jean Jenkins; Nancy Stevens; Colleen M McBride
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2008-11       Impact factor: 4.254

10.  Advancing genomic research and reducing health disparities: what can nurse scholars do?

Authors:  Cheedy Jaja; Robert Gibson; Shirley Quarles
Journal:  J Nurs Scholarsh       Date:  2013-03-01       Impact factor: 3.176

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