Literature DB >> 16257941

Stormy weather: race, gene expression, and the science of health disparities.

Nancy Krieger1.   

Abstract

In the current US political climate, conservative foundations are seeking to frame debates over determinants of racial/ethnic health disparities as a matter of "politically correct" unscientific ideology (concerning the health impacts of discrimination) vs scientific yet "politically incorrect" expertise rooted in biological facts (concerning genes). I draw on historical and contemporary examples to place conservative polemics in context, and also highlight fundamental flaws in their arguments involving the use of spurious categories (e.g., Caucasian), logical fallacies, temporal fallacies, and an erroneous emphasis on gene frequency over gene expression. The larger goal is to strengthen development of a more critical, reflexive, and rigorous science capable of generating evidence useful for rectifying--rather than perpetuating--social disparities in health.

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Year:  2005        PMID: 16257941      PMCID: PMC1449500          DOI: 10.2105/AJPH.2005.067108

Source DB:  PubMed          Journal:  Am J Public Health        ISSN: 0090-0036            Impact factor:   9.308


  26 in total

1.  Commentary: Society, biology and the logic of social epidemiology.

Authors:  N Krieger
Journal:  Int J Epidemiol       Date:  2001-02       Impact factor: 7.196

2.  Sick genes, sick individuals or sick populations with chronic disease? The emergence of diabetes and high blood pressure in African-origin populations.

Authors:  J K Cruickshank; J C Mbanya; R Wilks; B Balkau; N McFarlane-Anderson; T Forrester
Journal:  Int J Epidemiol       Date:  2001-02       Impact factor: 7.196

Review 3.  Creationism and intelligent design.

Authors:  Robert T Pennock
Journal:  Annu Rev Genomics Hum Genet       Date:  2003       Impact factor: 8.929

Review 4.  Does racism harm health? Did child abuse exist before 1962? On explicit questions, critical science, and current controversies: an ecosocial perspective.

Authors:  Nancy Krieger
Journal:  Am J Public Health       Date:  2003-02       Impact factor: 9.308

5.  "Bodies count," and body counts: social epidemiology and embodying inequality.

Authors:  Nancy Krieger; George Davey Smith
Journal:  Epidemiol Rev       Date:  2004       Impact factor: 6.222

6.  Medicine. Race and reification in science.

Authors:  Troy Duster
Journal:  Science       Date:  2005-02-18       Impact factor: 47.728

7.  Whole-genome patterns of common DNA variation in three human populations.

Authors:  David A Hinds; Laura L Stuve; Geoffrey B Nilsen; Eran Halperin; Eleazar Eskin; Dennis G Ballinger; Kelly A Frazer; David R Cox
Journal:  Science       Date:  2005-02-18       Impact factor: 47.728

8.  Changes in the disparities in chronic diseases during the course of the 20th century.

Authors:  Robert W Fogel
Journal:  Perspect Biol Med       Date:  2005       Impact factor: 1.416

Review 9.  Genetics of hair and skin color.

Authors:  Jonathan L Rees
Journal:  Annu Rev Genet       Date:  2003       Impact factor: 16.830

Review 10.  Racism, sexism, and social class: implications for studies of health, disease, and well-being.

Authors:  N Krieger; D L Rowley; A A Herman; B Avery; M T Phillips
Journal:  Am J Prev Med       Date:  1993 Nov-Dec       Impact factor: 5.043

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  56 in total

1.  The importance of considering both racial and socioeconomic disparities: A response to Collins and Alpert.

Authors:  Rebecca C Thurston; Karen A Matthews
Journal:  Soc Sci Med       Date:  2009-12       Impact factor: 4.634

2.  Methods for the scientific study of discrimination and health: an ecosocial approach.

Authors:  Nancy Krieger
Journal:  Am J Public Health       Date:  2012-03-15       Impact factor: 9.308

Review 3.  A critical review of racial/ethnic variables in osteoporosis and bone density research.

Authors:  M S Megyesi; L M Hunt; H Brody
Journal:  Osteoporos Int       Date:  2011-01-05       Impact factor: 4.507

4.  The ambiguous meanings of the racial/ethnic categories routinely used in human genetics research.

Authors:  Linda M Hunt; Mary S Megyesi
Journal:  Soc Sci Med       Date:  2007-10-23       Impact factor: 4.634

5.  Proximal, distal, and the politics of causation: what's level got to do with it?

Authors:  Nancy Krieger
Journal:  Am J Public Health       Date:  2008-01-02       Impact factor: 9.308

6.  The problem with the phrase women and minorities: intersectionality-an important theoretical framework for public health.

Authors:  Lisa Bowleg
Journal:  Am J Public Health       Date:  2012-05-17       Impact factor: 9.308

7.  Genes, race, and culture in clinical care: racial profiling in the management of chronic illness.

Authors:  Linda M Hunt; Nicole D Truesdell; Meta J Kreiner
Journal:  Med Anthropol Q       Date:  2013-06-26

8.  Racial-ethnic disparities in the association between risk factors and diabetes: The Northern Manhattan Study.

Authors:  Erin R Kulick; Yeseon P Moon; Ken Cheung; Joshua Z Willey; Ralph L Sacco; Mitchell S V Elkind
Journal:  Prev Med       Date:  2015-12-04       Impact factor: 4.018

9.  Comparison of statistical methods for estimating genetic admixture in a lung cancer study of African Americans and Latinos.

Authors:  Melinda C Aldrich; Steve Selvin; Helen M Hansen; Lisa F Barcellos; Margaret R Wrensch; Jennette D Sison; Charles P Quesenberry; Rick A Kittles; Gabriel Silva; Patricia A Buffler; Michael F Seldin; John K Wiencke
Journal:  Am J Epidemiol       Date:  2008-09-12       Impact factor: 4.897

10.  Perceptions of African-American health professionals and community members on the participation of children and pregnant women in genetic research.

Authors:  E M Ngui; T D Warner; L W Roberts
Journal:  Public Health Genomics       Date:  2013-11-06       Impact factor: 2.000

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