OBJECTIVE: Our aim was to compare detection, quantification, and cardiovascular risk stratification of coronary artery calcium (CAC) between electron beam CT and 16-MDCT with retrospective reconstruction. SUBJECTS AND METHODS. One hundred patients underwent both electron beam CT and 16-MDCT, and coronary artery calcium score, volume, and mass were obtained. RESULTS: Correlation between the two CT scanners was high for both calcium score (r(2) = 0.955), volume (r(2) = 0.952), and mass (r(2) = 0.977). Although electron beam CT is viewed as the gold standard, the sensitivity and specificity in the detection of CAC using 16-MDCT with a threshold of 130 H were 98.7% and 100%, respectively. The variability of calcium scores between the two CT scanners (26.5%) was comparable with two electron beam CT scanners reported previously. The variability of calcium volume (20.7%) and mass (20.3%) was lower than that of the score (Student's t test, r = 0.05, 0.01). In clinical cardiovascular risk stratification based on two CT calcium scores, the Cohen's kappa value was 0.929. There was no significant difference between the two scanners using Wilcoxon's signed rank test (p = 0.157). CONCLUSION: The 16-MDCT scanner with retrospective reconstruction, showing high agreement for detection and quantification of CAC with electron beam CT, holds promise in the detection of coronary artery atherosclerosis.
OBJECTIVE: Our aim was to compare detection, quantification, and cardiovascular risk stratification of coronary artery calcium (CAC) between electron beam CT and 16-MDCT with retrospective reconstruction. SUBJECTS AND METHODS. One hundred patients underwent both electron beam CT and 16-MDCT, and coronary artery calcium score, volume, and mass were obtained. RESULTS: Correlation between the two CT scanners was high for both calcium score (r(2) = 0.955), volume (r(2) = 0.952), and mass (r(2) = 0.977). Although electron beam CT is viewed as the gold standard, the sensitivity and specificity in the detection of CAC using 16-MDCT with a threshold of 130 H were 98.7% and 100%, respectively. The variability of calcium scores between the two CT scanners (26.5%) was comparable with two electron beam CT scanners reported previously. The variability of calcium volume (20.7%) and mass (20.3%) was lower than that of the score (Student's t test, r = 0.05, 0.01). In clinical cardiovascular risk stratification based on two CT calcium scores, the Cohen's kappa value was 0.929. There was no significant difference between the two scanners using Wilcoxon's signed rank test (p = 0.157). CONCLUSION: The 16-MDCT scanner with retrospective reconstruction, showing high agreement for detection and quantification of CAC with electron beam CT, holds promise in the detection of coronary artery atherosclerosis.
Authors: N Reinsch; A A Mahabadi; N Lehmann; S Möhlenkamp; C Hoefs; B Sievers; T Budde; R Seibel; K-H Jöckel; R Erbel Journal: Br J Radiol Date: 2011-10-18 Impact factor: 3.039
Authors: Matthijs Oudkerk; Arthur E Stillman; Sandra S Halliburton; Willi A Kalender; Stefan Möhlenkamp; Cynthia H McCollough; Rozemarijn Vliegenthart; Leslee J Shaw; William Stanford; Allen J Taylor; Peter M A van Ooijen; Lewis Wexler; Paolo Raggi Journal: Eur Radiol Date: 2008-07-24 Impact factor: 5.315
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Authors: Paul Stolzmann; Sebastian Leschka; Thomas Betschart; Lotus Desbiolles; Thomas G Flohr; Borut Marincek; Hatem Alkadhi Journal: Int J Cardiovasc Imaging Date: 2008-12-12 Impact factor: 2.357
Authors: Matthijs Oudkerk; Arthur E Stillman; Sandra S Halliburton; Willi A Kalender; Stefan Möhlenkamp; Cynthia H McCollough; Rozemarijn Vliegenthart; Leslee J Shaw; William Stanford; Allen J Taylor; Peter M A van Ooijen; Lewis Wexler; Paolo Raggi Journal: Int J Cardiovasc Imaging Date: 2008-05-27 Impact factor: 2.357
Authors: Philipp G C Begemann; Udo van Stevendaal; Ralph Koester; Andreas H Mahnken; Andreas Koops; Gerhard Adam; Michael Grass; Claus Nolte-Ernsting Journal: Eur Radiol Date: 2007-02-01 Impact factor: 7.034