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Literature DB >> 15183911

Synthesis and study of antibacterial and antifungal activities of novel 1-[2-(benzoxazol-2-yl)ethoxy]- 2,6-diarylpiperidin-4-ones.

C Ramalingan¹, S Balasubramanian, S Kabilan, M Vasudevan.

Abstract

Some novel benzoxazolylethoxypiperidones have been synthesized and their antibacterial activity against streptococcus faecalis, bacillus subtilis, escherichia coli, staphylococcus aureus aand pseudomonas aeruginosa and antifungal activity against Candida-6, Candida albicans, Aspergillus niger, Candida-51 and Aspergillus flavus were evaluated. Compounds 37, 38 and 39 exerted potent in vitro antibacterial activity against Streptococcus faecalis while compounds 40 and 41 exhibited potent in vitro antifungal activity against Candida-51.

Entities: Chemical Species

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Year: 2004 PMID： 15183911 DOI： 10.1016/j.ejmech.2004.02.005

Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514

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Cited

14 in total

1. Some metal chelates with Schiff base ligand: synthesis, structure elucidation, thermal behavior, XRD evaluation, antioxidant activity, enzyme inhibition, and molecular docking studies.

Authors: Nevin Turan; Kenan Buldurun; Fikret Türkan; Abdulmelik Aras; Naki Çolak; Manikanta Murahari; Ercan Bursal; Asim Mantarcı
Journal: Mol Divers Date: 2021-11-07 Impact factor: 3.364

2. Transition metal(II) complexes of a novel symmetrical benzothiazole-based ligand: synthesis, spectral/structural characterization and fluorescence properties.

Authors: Mehmet Gulcan; Yaşar Karataş; Sema Işık; Gülsiye Öztürk; Esvet Akbaş; Ertan Şahin
Journal: J Fluoresc Date: 2014-09-13 Impact factor: 2.217

Synthesis and study of antibacterial and antifungal activities of novel 1-[2-(benzoxazol-2-yl)ethoxy]- 2,6-diarylpiperidin-4-ones.

1. Some metal chelates with Schiff base ligand: synthesis, structure elucidation, thermal behavior, XRD evaluation, antioxidant activity, enzyme inhibition, and molecular docking studies.

2. Transition metal(II) complexes of a novel symmetrical benzothiazole-based ligand: synthesis, spectral/structural characterization and fluorescence properties.

3. Crystal structure of 4-methyl-N-[2-(piperidin-1-yl)eth-yl]benzamide monohydrate.

4. N-(2-Fluoro-benz-yloxy)-1,3,5-trimethyl-2,6-diphenyl-piperidin-4-imine.

5. (4E)-N-[(2-Chloro-phen-yl)meth-oxy]-1,3-dimethyl-2,6-diphenyl-piperidin-4-imine.

6. (4E)-N-[(2-Bromo-phen-yl)meth-oxy]-1,3-dimethyl-2,6-diphenyl-piperidin-4-imine.

7. 1-(2-Chloro-benz-yl)-3,5-dimethyl-2,6-diphenyl-piperidine.

8. 1-(2-Chloro-benz-yl)-3-methyl-2,6-diphenyl-piperidine.

9. Crystal structure of (4-hy-droxy-piperidin-1-yl)[4-(tri-fluoro-meth-yl)phen-yl]methanone.

10. 2-Chloro-1-(3,3-dimethyl-2,6-di-phenyl-piperidin-1-yl)ethanone.