Literature DB >> 15155236

Posaconazole therapy of disseminated phaeohyphomycosis in a murine model.

John R Graybill1, Laura K Najvar, Elizabeth Johnson, Rosie Bocanegra, David Loebenberg.   

Abstract

Immunocompetent (nu/+) and athymic (nu/nu) BALB/c mice were infected intravenously with Wangiella dermatitidis and treated with posaconazole. Posaconazole reduced the counts in tissues and prolonged survival. Of particular interest, posaconazole reduced the counts of this neurotropic pathogen in the brain.

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Year:  2004        PMID： 15155236      PMCID： PMC415573          DOI： 10.1128/AAC.48.6.2288-2291.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

1.  Comparison of a new triazole, posaconazole, with itraconazole and amphotericin B for treatment of histoplasmosis following pulmonary challenge in immunocompromised mice.

Authors:  P Connolly; L J Wheat; C Schnizlein-Bick; M Durkin; S Kohler; M Smedema; J Goldberg; E Brizendine; D Loebenberg
Journal:  Antimicrob Agents Chemother       Date:  2000-10       Impact factor: 5.191

2.  Efficacy of SCH56592 in a rabbit model of invasive aspergillosis.

Authors:  W R Kirkpatrick; R K McAtee; A W Fothergill; D Loebenberg; M G Rinaldi; T F Patterson
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

3.  Voriconazole treatment for less-common, emerging, or refractory fungal infections.

Authors:  John R Perfect; Kieren A Marr; Thomas J Walsh; Richard N Greenberg; Bertrand DuPont; Juliàn de la Torre-Cisneros; Gudrun Just-Nübling; Haran T Schlamm; Irja Lutsar; Ana Espinel-Ingroff; Elizabeth Johnson
Journal:  Clin Infect Dis       Date:  2003-04-22       Impact factor: 9.079

4.  Molecular cloning and characterization of WdPKS1, a gene involved in dihydroxynaphthalene melanin biosynthesis and virulence in Wangiella (Exophiala) dermatitidis.

Authors:  B Feng; X Wang; M Hauser; S Kaufmann; S Jentsch; G Haase; J M Becker; P J Szaniszlo
Journal:  Infect Immun       Date:  2001-03       Impact factor: 3.441

Review 5.  Phaeohyphomycosis caused by the fungal genera Bipolaris and Exserohilum. A report of 9 cases and review of the literature.

Authors:  R D Adam; M L Paquin; E A Petersen; M A Saubolle; M G Rinaldi; J G Corcoran; J N Galgiani; R E Sobonya
Journal:  Medicine (Baltimore)       Date:  1986-07       Impact factor: 1.889

6.  Alternaria sinusitis.

Authors:  M A Shugar; W W Montgomery; N E Hyslop
Journal:  Ann Otol Rhinol Laryngol       Date:  1981 May-Jun       Impact factor: 1.547

7.  In vitro and in vivo drug studies with three agents of central nervous system phaeohyphomycosis.

Authors:  D M Dixon; A Polak
Journal:  Chemotherapy       Date:  1987       Impact factor: 2.544

8.  Comparison of a new triazole antifungal agent, Schering 56592, with itraconazole and amphotericin B for treatment of histoplasmosis in immunocompetent mice.

Authors:  P Connolly; J Wheat; C Schnizlein-Bick; M Durkin; S Kohler; M Smedema; J Goldberg; E Brizendine; D Loebenberg
Journal:  Antimicrob Agents Chemother       Date:  1999-02       Impact factor: 5.191

9.  Activity of posaconazole against Pseudallescheria boydii: in vitro and in vivo assays.

Authors:  Gloria M González; Rolando Tijerina; Laura K Najvar; Rosie Bocanegra; Michael G Rinaldi; David Loebenberg; John R Graybill
Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191

10.  In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model.

Authors:  Qiu N Sun; Laura K Najvar; Rosie Bocanegra; David Loebenberg; John R Graybill
Journal:  Antimicrob Agents Chemother       Date:  2002-07       Impact factor: 5.191
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  14 in total

1.  Antifungal susceptibility patterns of opportunistic fungi in the genera Verruconis and Ochroconis.

Authors:  S Seyedmousavi; K Samerpitak; A J M M Rijs; W J G Melchers; J W Mouton; P E Verweij; G S de Hoog
Journal:  Antimicrob Agents Chemother       Date:  2014-03-31       Impact factor: 5.191

Review 2.  Black yeasts and their filamentous relatives: principles of pathogenesis and host defense.

Authors:  Seyedmojtaba Seyedmousavi; Mihai G Netea; Johan W Mouton; Willem J G Melchers; Paul E Verweij; G Sybren de Hoog
Journal:  Clin Microbiol Rev       Date:  2014-07       Impact factor: 26.132

3.  Reflections on the approach to treatment of a mycologic disaster.

Authors:  David A Stevens
Journal:  Antimicrob Agents Chemother       Date:  2013-02-05       Impact factor: 5.191

4.  What can we learn and what do we need to know amidst the iatrogenic outbreak of Exserohilum rostratum meningitis?

Authors:  Dimitrios P Kontoyiannis; David S Perlin; Emmanuel Roilides; Thomas J Walsh
Journal:  Clin Infect Dis       Date:  2013-05-06       Impact factor: 9.079

5.  Antifungal therapy in an athymic murine model of chromoblastomycosis by Fonsecaea pedrosoi.

Authors:  Enrique Calvo; F Javier Pastor; Emilio Mayayo; Pilar Hernández; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2011-05-16       Impact factor: 5.191

6.  Molecular and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry-Based Characterization of Clinically Significant Melanized Fungi in India.

Authors:  Ashutosh Singh; Pradeep Kumar Singh; Anil Kumar; Jagdish Chander; Geetika Khanna; Pradip Roy; Jacques F Meis; Anuradha Chowdhary
Journal:  J Clin Microbiol       Date:  2017-01-18       Impact factor: 5.948

Review 7.  Melanized fungi in human disease.

Authors:  Sanjay G Revankar; Deanna A Sutton
Journal:  Clin Microbiol Rev       Date:  2010-10       Impact factor: 26.132

8.  Fungal meningoencephalitis caused by Alternaria: a clinical case.

Authors:  Cícero J C Silveira; Joana Amaral; Rodrigo P Gorayeb; José Cabral; Teresa Pacheco
Journal:  Clin Drug Investig       Date:  2013-02       Impact factor: 2.859

9.  Murine model of a disseminated infection by the novel fungus Fonsecaea monophora and successful treatment with posaconazole.

Authors:  Enrique Calvo; F Javier Pastor; M Mar Rodríguez; Emilio Mayayo; Valentina Salas; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2009-12-14       Impact factor: 5.191

10.  Cytolocalization of the class V chitin synthase in the yeast, hyphal and sclerotic morphotypes of Wangiella (Exophiala) dermatitidis.

Authors:  Dariusz Abramczyk; Changwon Park; Paul J Szaniszlo
Journal:  Fungal Genet Biol       Date:  2008-10-21       Impact factor: 3.495
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