Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Murine model of a disseminated infection by the novel fungus Fonsecaea monophora and successful treatment with posaconazole.

Literature DB >> 20008773

Murine model of a disseminated infection by the novel fungus Fonsecaea monophora and successful treatment with posaconazole.

Enrique Calvo¹, F Javier Pastor, M Mar Rodríguez, Emilio Mayayo, Valentina Salas, Josep Guarro.

Abstract

We have evaluated the efficacy of posaconazole, amphotericin B, and itraconazole in a murine model of disseminated infection by Fonsecaea monophora. Of these three antifungal drugs tested, posaconazole prolonged survival significantly and reduced the fungal load in most of the organs tested. Bioassay studies demonstrated the relationship between posaconazole levels and dose escalation in serum and brain tissue. Posaconazole may have a clinical role in the treatment of disseminated infections by F. monophora.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2009 PMID： 20008773 PMCID： PMC2812182 DOI： 10.1128/AAC.01284-09

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Molecular ecology and pathogenic potential of Fonsecaea species.

Authors: G S De Hoog; D Attili-Angelis; V A Vicente; A H G Gerrits Van Den Ende; F Queiroz-Telles
Journal: Med Mycol Date: 2004-10 Impact factor: 4.076

2. Distribution and activity of amphotericin B in humans.

Authors: K J Christiansen; E M Bernard; J W Gold; D Armstrong
Journal: J Infect Dis Date: 1985-11 Impact factor: 5.226

3. Molecular diversity of Fonsecaea (Chaetothyriales) causing chromoblastomycosis in southern China.

Authors: Liyan Xi; Jiufeng Sun; Changming Lu; Honfang Liu; Zhi Xie; Kazutaka Fukushima; Kayoko Takizawa; Mohammad Javad Najafzadeh; G S De Hoog
Journal: Med Mycol Date: 2008-10-25 Impact factor: 4.076

4. Case study: posaconazole treatment of disseminated phaeohyphomycosis due to Exophiala spinifera.

Authors: Ricardo Negroni; Silvia Haydeé Helou; Nestor Petri; Ana María Robles; Alicia Arechavala; Mario Horacio Bianchi
Journal: Clin Infect Dis Date: 2004-01-13 Impact factor: 9.079

5. Combined antifungal therapy in a murine model of disseminated infection by Cladophialophora bantiana.

Authors: Marçal Mariné; F Javier Pastor; Josep Guarro
Journal: Med Mycol Date: 2008-12-12 Impact factor: 4.076

6. Chromoblastomycosis caused by a meristematic mutant of Fonsecaea monophora.

Authors: Liyan Xi; Changming Lu; Jiufeng Sun; Xiqing Li; Honfang Liu; Junmin Zhang; Zhi Xie; G S De Hoog
Journal: Med Mycol Date: 2008-09-15 Impact factor: 4.076

7. Genetic diversity and species delimitation in the opportunistic genus Fonsecaea.

Authors: M J Najafzadeh; C Gueidan; H Badali; A H G Gerrits Van Den Ende; Lian Xi; G S De Hoog
Journal: Med Mycol Date: 2008-12-19 Impact factor: 4.076

8. Optimization of bioassay method for the quantitative microbiological determination of amphotericin B.

Authors: András Fittler; Béla Kocsis; Imre Gerlinger; Lajos Botz
Journal: Mycoses Date: 2009-01-14 Impact factor: 4.377

9. Posaconazole therapy of disseminated phaeohyphomycosis in a murine model.

Authors: John R Graybill; Laura K Najvar; Elizabeth Johnson; Rosie Bocanegra; David Loebenberg
Journal: Antimicrob Agents Chemother Date: 2004-06 Impact factor: 5.191

10. Simplified bioassay method for measurement of flucytosine or ketoconazole.

Authors: C A Bodet; J H Jorgensen; D J Drutz
Journal: J Clin Microbiol Date: 1985-08 Impact factor: 5.948

13 in total

1. Antifungal susceptibility patterns of opportunistic fungi in the genera Verruconis and Ochroconis.

Authors: S Seyedmousavi; K Samerpitak; A J M M Rijs; W J G Melchers; J W Mouton; P E Verweij; G S de Hoog
Journal: Antimicrob Agents Chemother Date: 2014-03-31 Impact factor: 5.191

2. Low Central Nervous System Posaconazole Concentrations during Cerebral Phaeohyphomycosis.

Authors: François Barde; Eliane Billaud; Lauriane Goldwirt; Catherine Horodyckid; Vincent Jullien; Fanny Lanternier; Philippe Lesprit; Lucie Limousin; Jérémie F Cohen; Olivier Lortholary
Journal: Antimicrob Agents Chemother Date: 2019-10-22 Impact factor: 5.191

Review 3. Black yeasts and their filamentous relatives: principles of pathogenesis and host defense.

Authors: Seyedmojtaba Seyedmousavi; Mihai G Netea; Johan W Mouton; Willem J G Melchers; Paul E Verweij; G Sybren de Hoog
Journal: Clin Microbiol Rev Date: 2014-07 Impact factor: 26.132

4. Antifungal therapy in an athymic murine model of chromoblastomycosis by Fonsecaea pedrosoi.

Authors: Enrique Calvo; F Javier Pastor; Emilio Mayayo; Pilar Hernández; Josep Guarro
Journal: Antimicrob Agents Chemother Date: 2011-05-16 Impact factor: 5.191

Review 5. Therapeutic Challenges of Non-Aspergillus Invasive Mold Infections in Immunosuppressed Patients.

Authors: Frederic Lamoth; Dimitrios P Kontoyiannis
Journal: Antimicrob Agents Chemother Date: 2019-10-22 Impact factor: 5.191

Review 6. Melanized fungi in human disease.

Authors: Sanjay G Revankar; Deanna A Sutton
Journal: Clin Microbiol Rev Date: 2010-10 Impact factor: 26.132