Literature DB >> 23650291

What can we learn and what do we need to know amidst the iatrogenic outbreak of Exserohilum rostratum meningitis?

Dimitrios P Kontoyiannis1, David S Perlin, Emmanuel Roilides, Thomas J Walsh.   

Abstract

The tragedy of the ongoing epidemic of meningitis caused by Exserohilum rostratum brings into focus the epidemiology, risk factors, pathogenesis, diagnosis, and treatment of a multitude of opportunistic mold infections of the central nervous system. Herein we provide our perspective regarding the translational research objectives of this infection that are needed to make an impact on this important healthcare crisis.

Entities:  

Keywords:  Exserohilum rostratum; antifungals; meningoencephalitis; pathogenesis; risk factors

Mesh：

Substances：

Year:  2013        PMID： 23650291      PMCID： PMC3888152          DOI： 10.1093/cid/cit283

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  42 in total

1.  Update on emerging infections: news from the Centers for Disease Control and Prevention. Notes from the field: fatal fungal soft-tissue infections after a tornado--Joplin, Missouri, 2011.

Authors:  Jeffrey P Green; David J Karras
Journal:  Ann Emerg Med       Date:  2012-01       Impact factor: 5.721

Review 2.  Evaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections.

Authors:  Joanne Livermore; William Hope
Journal:  Expert Opin Drug Metab Toxicol       Date:  2012-04-25       Impact factor: 4.481

3.  Multistate fungal meningitis outbreak -- interim guidance for treatment.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2012-10-19       Impact factor: 17.586

4.  Molecular identification and in vitro response to antifungal drugs of clinical isolates of Exserohilum.

Authors:  Keith Cássia da Cunha; Deanna A Sutton; Josepa Gené; Javier Capilla; Josep Cano; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2012-06-25       Impact factor: 5.191

5.  Identification of a high-affinity binder for estradiol and a low-affinity binder for testosterone in Coccidioides immitis.

Authors:  B L Powell; D J Drutz
Journal:  Infect Immun       Date:  1984-09       Impact factor: 3.441

6.  Comparison of fluconazole and itraconazole in a rabbit model of coccidioidal meningitis.

Authors:  K N Sorensen; R A Sobel; K V Clemons; D Pappagianis; D A Stevens; P L Williams
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

7.  Caspofungin therapy of neonates with invasive candidiasis.

Authors:  Carla M Odio; Roberto Araya; Luis E Pinto; Carlos E Castro; Sergio Vasquez; Braulio Alfaro; Alberto Sàenz; Marco L Herrera; Thomas J Walsh
Journal:  Pediatr Infect Dis J       Date:  2004-12       Impact factor: 2.129

8.  Estrogens inhibit mycelium-to-yeast transformation in the fungus Paracoccidioides brasiliensis: implications for resistance of females to paracoccidioidomycosis.

Authors:  A Restrepo; M E Salazar; L E Cano; E P Stover; D Feldman; D A Stevens
Journal:  Infect Immun       Date:  1984-11       Impact factor: 3.441

Review 9.  Color me bad: microbial pigments as virulence factors.

Authors:  George Y Liu; Victor Nizet
Journal:  Trends Microbiol       Date:  2009-08-31       Impact factor: 17.079

10.  Influence of 17β-estradiol on gene expression of Paracoccidioides during mycelia-to-yeast transition.

Authors:  Jata Shankar; Thomas D Wu; Karl V Clemons; Jomar P Monteiro; Laurence F Mirels; David A Stevens
Journal:  PLoS One       Date:  2011-12-14       Impact factor: 3.240
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  6 in total

1.  In Vitro Activities of Eight Antifungal Drugs against a Global Collection of Genotyped Exserohilum Isolates.

Authors:  Anuradha Chowdhary; Ferry Hagen; Ilse Curfs-Breuker; Hugo Madrid; G Sybren de Hoog; Jacques F Meis
Journal:  Antimicrob Agents Chemother       Date:  2015-08-03       Impact factor: 5.191

2.  Fungal disease following contaminated steroid injections: Exserohilum is ready for its close-up.

Authors:  Marta Feldmesser
Journal:  Am J Pathol       Date:  2013-07-19       Impact factor: 4.307

3.  CNS Mold Infections.

Authors:  Jennifer L Lyons
Journal:  Curr Infect Dis Rep       Date:  2013-10-13       Impact factor: 3.725

4.  Outbreak of fungal infections associated with contaminated methylprednisolone acetate: an update.

Authors:  April C Pettit; Anurag N Malani
Journal:  Curr Infect Dis Rep       Date:  2015-01       Impact factor: 3.725

Review 5.  Mold infections of the central nervous system.

Authors:  Matthew McCarthy; Axel Rosengart; Audrey N Schuetz; Dimitrios P Kontoyiannis; Thomas J Walsh
Journal:  N Engl J Med       Date:  2014-07-10       Impact factor: 91.245

6.  Preliminary laboratory report of fungal infections associated with contaminated methylprednisolone injections.

Authors:  Shawn R Lockhart; Cau D Pham; Lalitha Gade; Naureen Iqbal; Christina M Scheel; Angela A Cleveland; Anne M Whitney; Judith Noble-Wang; Tom M Chiller; Benjamin J Park; Anastasia P Litvintseva; Mary E Brandt
Journal:  J Clin Microbiol       Date:  2013-06-12       Impact factor: 5.948
  6 in total

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