| Literature DB >> 12654687 |
Gloria M González1, Rolando Tijerina, Laura K Najvar, Rosie Bocanegra, Michael G Rinaldi, David Loebenberg, John R Graybill.
Abstract
Thirty isolates of Pseudallescheria boydii were tested to compare the in vitro activity of posaconazole with those of fluconazole and itraconazole, using NCCLS methods. Posaconazole was evaluated in an immunosuppressed mouse model of disseminated pseudallescheriasis. Posaconazole was more effective than itraconazole and as effective as fluconazole in preventing death and significantly reducing the CFU of P. boydii from tissues.Entities:
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Year: 2003 PMID: 12654687 PMCID: PMC152491 DOI: 10.1128/AAC.47.4.1436-1438.2003
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191