Literature DB >> 15025448

Direct detection of homocysteine.

Weihua Wang1, Jorge O Escobedo, Candace M Lawrence, Robert M Strongin.   

Abstract

Homocysteine (Hcy) is a biomarker for significant disorders including Alzheimer's and cardiovascular disease. The monitoring of Hcy levels in plasma is of current concern. We describe highly selective colorimetric methods for the direct detection of Hcy. Inexpensive, commercially available materials are employed. The results show potential application for the detection of Hcy in human blood plasma.

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Year:  2004        PMID： 15025448      PMCID： PMC3376413          DOI： 10.1021/ja0318838

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  12 in total

1.  Visual sensing of saccharides promoted by resorcinol condensation products

Authors: 
Journal:  Org Lett       Date:  2000-03-09       Impact factor: 6.005

2.  Simple and rapid visual sensing of saccharides.

Authors:  C J Davis; P T Lewis; M E McCarroll; M W Read; R Cueto; R M Strongin
Journal:  Org Lett       Date:  1999-07-29       Impact factor: 6.005

Review 3.  Roles of homocysteine in cell metabolism: old and new functions.

Authors:  M Medina; J L Urdiales; M I Amores-Sánchez
Journal:  Eur J Biochem       Date:  2001-07

4.  Chromophore formation in resorcinarene solutions and the visual detection of mono- and oligosaccharides.

Authors:  Ming He; Rolanda J Johnson; Jorge O Escobedo; Patricia A Beck; Kyu Kwang Kim; Nadia N St Luce; Claude J Davis; Patrick T Lewis; Frank R Fronczek; Bruce J Melancon; Anthony A Mrse; W Dale Treleaven; Robert M Strongin
Journal:  J Am Chem Soc       Date:  2002-05-08       Impact factor: 15.419

5.  Postcolumn HPLC detection of mono- and oligosaccharides with a chemosensor.

Authors:  Kyu Kwang Kim; Jorge O Escobedo; Nadia N St Luce; Oleksandr Rusin; Douglas Wong; Robert M Strongin
Journal:  Org Lett       Date:  2003-12-25       Impact factor: 6.005

6.  Analytical determination of homocysteine: a review.

Authors:  Olga Nekrassova; Nathan S Lawrence; Richard G Compton
Journal:  Talanta       Date:  2003-08-29       Impact factor: 6.057

7.  Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.

Authors:  Sudha Seshadri; Alexa Beiser; Jacob Selhub; Paul F Jacques; Irwin H Rosenberg; Ralph B D'Agostino; Peter W F Wilson; Philip A Wolf
Journal:  N Engl J Med       Date:  2002-02-14       Impact factor: 91.245

Review 8.  Homocysteine and cardiovascular disease.

Authors:  H Refsum; P M Ueland; O Nygård; S E Vollset
Journal:  Annu Rev Med       Date:  1998       Impact factor: 13.739

9.  Reduction of dehydroascorbic acid by homocysteine.

Authors:  J B Park
Journal:  Biochim Biophys Acta       Date:  2001-02-16

10.  Visual detection of cysteine and homocysteine.

Authors:  Oleksandr Rusin; Nadia N St Luce; Rezik A Agbaria; Jorge O Escobedo; Shan Jiang; Isiah M Warner; Fareed B Dawan; Kun Lian; Robert M Strongin
Journal:  J Am Chem Soc       Date:  2004-01-21       Impact factor: 15.419
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  16 in total

1.  A convenient preparation of xanthene dyes.

Authors:  Youjun Yang; Jorge O Escobedo; Alexander Wong; Corin M Schowalter; Michael C Touchy; Lijuan Jiao; William E Crowe; Frank R Fronczek; Robert M Strongin
Journal:  J Org Chem       Date:  2005-08-19       Impact factor: 4.354

2.  Chemical methods for the detection of protein N-homocysteinylation via selective reactions with aldehydes.

Authors:  Tianzhu Zang; Shujia Dai; Dajun Chen; Bobby W K Lee; Suli Liu; Barry L Karger; Zhaohui Sunny Zhou
Journal:  Anal Chem       Date:  2009-11-01       Impact factor: 6.986

3.  The application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects.

Authors:  Kristin Fathe; Maria D Person; Richard H Finnell
Journal:  J Nutr Biochem       Date:  2014-11-12       Impact factor: 6.048

4.  Detection of homocysteine and cysteine.

Authors:  Weihua Wang; Oleksandr Rusin; Xiangyang Xu; Kyu Kwang Kim; Jorge O Escobedo; Sayo O Fakayode; Kristin A Fletcher; Mark Lowry; Corin M Schowalter; Candace M Lawrence; Frank R Fronczek; Isiah M Warner; Robert M Strongin
Journal:  J Am Chem Soc       Date:  2005-11-16       Impact factor: 15.419

5.  Use of a commercially available reagent for the selective detection of homocysteine in plasma.

Authors:  Jorge O Escobedo; Weihua Wang; Robert M Strongin
Journal:  Nat Protoc       Date:  2006       Impact factor: 13.491

6.  Electrochemical detection of glutathione using redox indicators.

Authors:  Eden Joy Pacsial-Ong; Robin L McCarley; Weihua Wang; Robert M Strongin
Journal:  Anal Chem       Date:  2006-11-01       Impact factor: 6.986

7.  Homocystamides promote free-radical and oxidative damage to proteins.

Authors:  Martha Sibrian-Vazquez; Jorge O Escobedo; Soojin Lim; George K Samoei; Robert M Strongin
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-18       Impact factor: 11.205

8.  A dual emission fluorescent probe enables simultaneous detection of glutathione and cysteine/homocysteine.

Authors:  Xiao-Feng Yang; Qian Huang; Yaogang Zhong; Zheng Li; Hua Li; Mark Lowry; Jorge O Escobedo; Robert M Strongin
Journal:  Chem Sci       Date:  2014-06-01       Impact factor: 9.825

9.  A photochemical method for determining plasma homocysteine with limited sample processing.

Authors:  Lovemore Hakuna; Jorge O Escobedo; Mark Lowry; Aabha Barve; Naneki McCallum; Robert M Strongin
Journal:  Chem Commun (Camb)       Date:  2014-03-21       Impact factor: 6.222

10.  Exploring the pH dependence of viologen reduction by alpha-carbon radicals derived from HCy and Cys.

Authors:  Dong Wang; William E Crowe; Robert M Strongin; Martha Sibrian-Vazquez
Journal:  Chem Commun (Camb)       Date:  2009-03-03       Impact factor: 6.222
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