Literature DB >> 14719920

Visual detection of cysteine and homocysteine.

Oleksandr Rusin1, Nadia N St Luce, Rezik A Agbaria, Jorge O Escobedo, Shan Jiang, Isiah M Warner, Fareed B Dawan, Kun Lian, Robert M Strongin.   

Abstract

The determination of cysteine and homocysteine levels is of great current interest for the monitoring of desease states. A new colorimetric method for the simultaneous detection of l-cysteine and l-homocysteine has been developed. A fluorescein derivative reacts with the above amino acids, producing their respective thiazolidines resulting in color changes. Interference from other amino acids and proteins is minimal.

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Year:  2004        PMID： 14719920      PMCID： PMC3376414          DOI： 10.1021/ja036297t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  16 in total

1.  Visual sensing of saccharides promoted by resorcinol condensation products

Authors: 
Journal:  Org Lett       Date:  2000-03-09       Impact factor: 6.005

2.  Simple and rapid visual sensing of saccharides.

Authors:  C J Davis; P T Lewis; M E McCarroll; M W Read; R Cueto; R M Strongin
Journal:  Org Lett       Date:  1999-07-29       Impact factor: 6.005

3.  Chromophore formation in resorcinarene solutions and the visual detection of mono- and oligosaccharides.

Authors:  Ming He; Rolanda J Johnson; Jorge O Escobedo; Patricia A Beck; Kyu Kwang Kim; Nadia N St Luce; Claude J Davis; Patrick T Lewis; Frank R Fronczek; Bruce J Melancon; Anthony A Mrse; W Dale Treleaven; Robert M Strongin
Journal:  J Am Chem Soc       Date:  2002-05-08       Impact factor: 15.419

4.  Analytical determination of homocysteine: a review.

Authors:  Olga Nekrassova; Nathan S Lawrence; Richard G Compton
Journal:  Talanta       Date:  2003-08-29       Impact factor: 6.057

5.  New methods for proteomic research: preparation of proteins with N-terminal cysteines for labeling and conjugation.

Authors:  Thomas J Tolbert; Chi-Huey Wong
Journal:  Angew Chem Int Ed Engl       Date:  2002-06-17       Impact factor: 15.336

6.  Assays for total homocysteine and other thiols by capillary electrophoresis-laser-induced fluorescence detection. I. Preanalytical condition studies.

Authors:  E Caussé; C Issac; P Malatray; C Bayle; P Valdiguié; R Salvayre; F Couderc
Journal:  J Chromatogr A       Date:  2000-10-20       Impact factor: 4.759

7.  Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distribution.

Authors:  S C Burdette; G K Walkup; B Spingler; R Y Tsien; S J Lippard
Journal:  J Am Chem Soc       Date:  2001-08-15       Impact factor: 15.419

Review 8.  Homocysteine and cardiovascular disease.

Authors:  H Refsum; P M Ueland; O Nygård; S E Vollset
Journal:  Annu Rev Med       Date:  1998       Impact factor: 13.739

9.  Detection of homocysteine by conventional and microchip capillary electrophoresis/electrochemistry.

Authors:  Stephanie A Pasas; Nathan A Lacher; Malonne I Davies; Susan M Lunte
Journal:  Electrophoresis       Date:  2002-03       Impact factor: 3.535

10.  On the chemistry and biochemistry of 3-mercaptopyruvic acid, the alpha-keto acid analog of cysteine.

Authors:  A J Cooper; M T Haber; A Meister
Journal:  J Biol Chem       Date:  1982-01-25       Impact factor: 5.157
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  34 in total

1.  Conjugate addition/cyclization sequence enables selective and simultaneous fluorescence detection of cysteine and homocysteine.

Authors:  Xiaofeng Yang; Yixing Guo; Robert M Strongin
Journal:  Angew Chem Int Ed Engl       Date:  2011-09-20       Impact factor: 15.336

2.  Fluorescein Tri-Aldehyde Promotes the Selective Detection of Homocysteine.

Authors:  Aabha Barve; Mark Lowry; Jorge O Escobedo; Josephrajan Thainashmuthu; Robert M Strongin
Journal:  J Fluoresc       Date:  2016-01-16       Impact factor: 2.217

3.  Chemical methods for the detection of protein N-homocysteinylation via selective reactions with aldehydes.

Authors:  Tianzhu Zang; Shujia Dai; Dajun Chen; Bobby W K Lee; Suli Liu; Barry L Karger; Zhaohui Sunny Zhou
Journal:  Anal Chem       Date:  2009-11-01       Impact factor: 6.986

4.  A New Turn on Fluorescent Probe for Selective Detection of Cysteine/Homocysteine.

Authors:  Puhui Xie; Guangqin Gao; Juanjuan Liu; Qiu Jin; Guoyu Yang
Journal:  J Fluoresc       Date:  2015-07-17       Impact factor: 2.217

5.  Detection of homocysteine and cysteine.

Authors:  Weihua Wang; Oleksandr Rusin; Xiangyang Xu; Kyu Kwang Kim; Jorge O Escobedo; Sayo O Fakayode; Kristin A Fletcher; Mark Lowry; Corin M Schowalter; Candace M Lawrence; Frank R Fronczek; Isiah M Warner; Robert M Strongin
Journal:  J Am Chem Soc       Date:  2005-11-16       Impact factor: 15.419

Review 6.  Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH.

Authors:  Cai-Xia Yin; Kang-Ming Xiong; Fang-Jun Huo; James C Salamanca; Robert M Strongin
Journal:  Angew Chem Int Ed Engl       Date:  2017-09-22       Impact factor: 15.336

7.  A seminaphthofluorescein-based fluorescent chemodosimeter for the highly selective detection of cysteine.

Authors:  Xiaofeng Yang; Yixing Guo; Robert M Strongin
Journal:  Org Biomol Chem       Date:  2012-03-05       Impact factor: 3.876

8.  Detection of biological thiols based on a colorimetric method.

Authors:  Yuan-Yuan Xu; Yang-Yang Sun; Yu-Juan Zhang; Chen-He Lu; Jin-Feng Miao
Journal:  J Zhejiang Univ Sci B       Date:  2016 Oct.       Impact factor: 3.066

9.  Differences in heterocycle basicity distinguish homocysteine from cysteine using aldehyde-bearing fluorophores.

Authors:  Aabha Barve; Mark Lowry; Jorge O Escobedo; Katherine T Huynh; Lovemore Hakuna; Robert M Strongin
Journal:  Chem Commun (Camb)       Date:  2014-08-04       Impact factor: 6.222

10.  A dual emission fluorescent probe enables simultaneous detection of glutathione and cysteine/homocysteine.

Authors:  Xiao-Feng Yang; Qian Huang; Yaogang Zhong; Zheng Li; Hua Li; Mark Lowry; Jorge O Escobedo; Robert M Strongin
Journal:  Chem Sci       Date:  2014-06-01       Impact factor: 9.825
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