| Literature DB >> 15020052 |
Davide F V Corona1, John W Tamkun.
Abstract
ISWI functions as the ATPase subunit of multiple chromatin-remodeling complexes. These complexes use the energy of ATP hydrolysis to slide nucleosomes and increase chromatin fluidity, thereby modulating the access of transcription factors and other regulatory proteins to DNA. Here we discuss recent progress toward understanding the biological functions of ISWI, with an emphasis on its roles in transcription, chromosome organization and DNA replication.Entities:
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Year: 2004 PMID： 15020052 DOI： 10.1016/j.bbaexp.2003.09.018
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002