Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Epigenetic control of aging.

Literature DB >> 20518699

Epigenetic control of aging.

Abstract

Organismal aging and longevity are influenced by many complex interacting factors. Epigenetics has recently emerged as another possible determinant of aging. Here, we review some of the epigenetic pathways that contribute to cellular senescence and age-associated phenotypes. Strategies aimed to reverse age-linked epigenetic alterations may lead to the development of new therapeutic interventions to delay or alleviate some of the most debilitating age-associated diseases.

Mesh：

Year: 2010 PMID： 20518699 PMCID： PMC3014766 DOI： 10.1089/ars.2010.3250

Source DB: PubMed Journal: Antioxid Redox Signal ISSN： 1523-0864 Impact factor: 8.401

243 in total

1. Normal prion protein has an activity like that of superoxide dismutase.

Authors: D R Brown; B S Wong; F Hafiz; C Clive; S J Haswell; I M Jones
Journal: Biochem J Date: 1999-11-15 Impact factor: 3.857

Review 2. New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin.

Authors: Simon W-L Chan; Elizabeth H Blackburn
Journal: Oncogene Date: 2002-01-21 Impact factor: 9.867

Review 3. Multivalent engagement of chromatin modifications by linked binding modules.

Authors: Alexander J Ruthenburg; Haitao Li; Dinshaw J Patel; C David Allis
Journal: Nat Rev Mol Cell Biol Date: 2007-12 Impact factor: 94.444

4. Interchromosomal interactions and olfactory receptor choice.

Authors: Stavros Lomvardas; Gilad Barnea; David J Pisapia; Monica Mendelsohn; Jennifer Kirkland; Richard Axel
Journal: Cell Date: 2006-07-28 Impact factor: 41.582

5. Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.

Authors: Bernhard Lehnertz; Yoshihide Ueda; Alwin A H A Derijck; Ulrich Braunschweig; Laura Perez-Burgos; Stefan Kubicek; Taiping Chen; En Li; Thomas Jenuwein; Antoine H F M Peters
Journal: Curr Biol Date: 2003-07-15 Impact factor: 10.834

6. The role of chondrocyte senescence in osteoarthritis.

Authors: Jo S Price; Jasmine G Waters; Clare Darrah; Caroline Pennington; Dylan R Edwards; Simon T Donell; Ian M Clark
Journal: Aging Cell Date: 2002-10 Impact factor: 9.304

7. SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation.

Authors: Alejandro Vaquero; Michael Scher; Hediye Erdjument-Bromage; Paul Tempst; Lourdes Serrano; Danny Reinberg
Journal: Nature Date: 2007-11-15 Impact factor: 49.962

8. LSH cooperates with DNA methyltransferases to repress transcription.

Authors: Kevin Myant; Irina Stancheva
Journal: Mol Cell Biol Date: 2007-10-29 Impact factor: 4.272

Review 9. MicroRNAs (miRNAs) in neurodegenerative diseases.

Authors: Peter T Nelson; Wang-Xia Wang; Bernard W Rajeev
Journal: Brain Pathol Date: 2008-01 Impact factor: 6.508

10. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Authors: Jill C Milne; Philip D Lambert; Simon Schenk; David P Carney; Jesse J Smith; David J Gagne; Lei Jin; Olivier Boss; Robert B Perni; Chi B Vu; Jean E Bemis; Roger Xie; Jeremy S Disch; Pui Yee Ng; Joseph J Nunes; Amy V Lynch; Hongying Yang; Heidi Galonek; Kristine Israelian; Wendy Choy; Andre Iffland; Siva Lavu; Oliver Medvedik; David A Sinclair; Jerrold M Olefsky; Michael R Jirousek; Peter J Elliott; Christoph H Westphal
Journal: Nature Date: 2007-11-29 Impact factor: 49.962

36 in total

Review 1. Gadd45 proteins: relevance to aging, longevity and age-related pathologies.

Authors: Alexey A Moskalev; Zeljka Smit-McBride; Mikhail V Shaposhnikov; Ekaterina N Plyusnina; Alex Zhavoronkov; Arie Budovsky; Robi Tacutu; Vadim E Fraifeld
Journal: Ageing Res Rev Date: 2011-10-05 Impact factor: 10.895

2. Global heterochromatin loss: a unifying theory of aging?

Authors: Amy Tsurumi; Willis X Li
Journal: Epigenetics Date: 2012-07-01 Impact factor: 4.528

3. Prospects and perspectives in primate aging research.

Authors: Rozalyn M Anderson; Ricki J Colman
Journal: Antioxid Redox Signal Date: 2010-10-12 Impact factor: 8.401

Review 4. Epigenetic regulation of redox signaling in diabetic retinopathy: Role of Nrf2.

Authors: Renu A Kowluru; Manish Mishra
Journal: Free Radic Biol Med Date: 2016-12-22 Impact factor: 7.376

Review 5. Epigenetic linkage of aging, cancer and nutrition.

Authors: Michael Daniel; Trygve O Tollefsbol
Journal: J Exp Biol Date: 2015-01-01 Impact factor: 3.312

6. Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women.

Authors: Matthew M Roforth; Joshua N Farr; Koji Fujita; Louise K McCready; Elizabeth J Atkinson; Terry M Therneau; Julie M Cunningham; Matthew T Drake; David G Monroe; Sundeep Khosla
Journal: Bone Date: 2015-03-27 Impact factor: 4.398

Review 7. Caloric restriction: beneficial effects on brain aging and Alzheimer's disease.

Authors: Caroline Van Cauwenberghe; Charysse Vandendriessche; Claude Libert; Roosmarijn E Vandenbroucke
Journal: Mamm Genome Date: 2016-05-30 Impact factor: 2.957

8. Abnormal DNA methylation in oocytes could be associated with a decrease in reproductive potential in old mice.

Authors: Ming-xing Yue; Xiang-wei Fu; Guang-bin Zhou; Yun-peng Hou; Ming DU; Liang Wang; Shi-en Zhu
Journal: J Assist Reprod Genet Date: 2012-05-18 Impact factor: 3.412

Review 9. MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus.

Authors: Bérénice A Benayoun; Changhan Lee
Journal: Bioessays Date: 2019-08-05 Impact factor: 4.345

10. Short term methionine restriction increases hepatic global DNA methylation in adult but not young male C57BL/6J mice.

Authors: Dwight A L Mattocks; Samantha J Mentch; Jelena Shneyder; Gene P Ables; Dongxiao Sun; John P Richie; Jason W Locasale; Sailendra N Nichenametla
Journal: Exp Gerontol Date: 2016-12-07 Impact factor: 4.032