Literature DB >> 14995053

Flaxseed and cardiovascular risk.

LeAnne T Bloedon1, Philippe O Szapary.   

Abstract

Flaxseed has recently gained attention in the area of cardiovascular disease primarily because it is the richest known source of both alpha-linolenic acid (ALA) and the phytoestrogen, lignans, as well as being a good source of soluble fiber. Human studies have shown that flaxseed can modestly reduce serum total and low-density lipoprotein cholesterol concentrations, reduce postprandial glucose absorption, decrease some markers of inflammation, and raise serum levels of the omega-3 fatty acids, ALA and eicosapentaenoic acid. Data on the antiplatelet, antioxidant, and hypotensive effects of flaxseed, however, are inconclusive. More research is needed to define the role of this functional food in reducing cardiovascular risk.

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Year:  2004        PMID: 14995053     DOI: 10.1111/j.1753-4887.2004.tb00002.x

Source DB:  PubMed          Journal:  Nutr Rev        ISSN: 0029-6643            Impact factor:   7.110


  27 in total

Review 1.  The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid.

Authors:  Delfin Rodriguez-Leyva; Chantal M C Dupasquier; Richelle McCullough; Grant N Pierce
Journal:  Can J Cardiol       Date:  2010-11       Impact factor: 5.223

Review 2.  Herbal Approach for Management of Atherosclerosis: a Review.

Authors:  Sanjiv Singh
Journal:  Curr Atheroscler Rep       Date:  2019-02-28       Impact factor: 5.113

3.  The effect of flaxseed dose on circulating concentrations of alpha-linolenic acid and secoisolariciresinol diglucoside derived enterolignans in young, healthy adults.

Authors:  Andrea L Edel; Amanda F Patenaude; Melanie N Richard; Elena Dibrov; J Alejandro Austria; Harold M Aukema; Grant N Pierce; Michel Aliani
Journal:  Eur J Nutr       Date:  2015-03-26       Impact factor: 5.614

4.  Meta-analysis of the effects of flaxseed interventions on blood lipids.

Authors:  An Pan; Danxia Yu; Wendy Demark-Wahnefried; Oscar H Franco; Xu Lin
Journal:  Am J Clin Nutr       Date:  2009-06-10       Impact factor: 7.045

Review 5.  Effects of soluble dietary fiber on low-density lipoprotein cholesterol and coronary heart disease risk.

Authors:  Lydia A Bazzano
Journal:  Curr Atheroscler Rep       Date:  2008-12       Impact factor: 5.113

6.  Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes.

Authors:  Floyd Dukes; Stathis Kanterakis; James Lee; Ralph Pietrofesa; Emily S Andersen; Evguenia Arguiri; Sonia Tyagi; Louise Showe; Yassine Amrani; Melpo Christofidou-Solomidou
Journal:  BMC Complement Altern Med       Date:  2012-04-20       Impact factor: 3.659

7.  Dietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice.

Authors:  Melpo Christofidou-Solomidou; Sonia Tyagi; Kay-See Tan; Sarah Hagan; Ralph Pietrofesa; Floyd Dukes; Evguenia Arguiri; Daniel F Heitjan; Charalambos C Solomides; Keith A Cengel
Journal:  BMC Cancer       Date:  2011-06-24       Impact factor: 4.430

8.  Role of natural herbs in the treatment of hypertension.

Authors:  Nahida Tabassum; Feroz Ahmad
Journal:  Pharmacogn Rev       Date:  2011-01

9.  Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer.

Authors:  Wendy Demark-Wahnefried; Stephen L George; Boyd R Switzer; Denise C Snyder; John F Madden; Thomas J Polascik; Mack T Ruffin; Robin T Vollmer
Journal:  Clin Trials       Date:  2008       Impact factor: 2.486

10.  Effect of flaxseed supplementation and exercise training on lipid profile, oxidative stress and inflammation in rats with myocardial ischemia.

Authors:  Howaida A Nounou; Maha M Deif; Manal A Shalaby
Journal:  Lipids Health Dis       Date:  2012-10-05       Impact factor: 3.876

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