Sanjiv Singh1. 1. Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Science and Education, Export Promotions Industrial Park (EPIP), Industrial Area, Dist: Vaishali, Hajipur, Bihar, 844102, India. sanjivpg2006@yahoo.com.
Abstract
PURPOSE OF REVIEW: Summarize of the reports on antioxidants especially from herbal sources which battle oxidative stress might be proficient to forestall and repair the free radical-prompted vascular damages in overseeing of atherosclerosis. RECENT FINDINGS: Atherosclerosis is the one of the fundamental reason for hypertension, stroke, myocardial localized necrosis, and numerous other cardiovascular illnesses. Atherosclerosis associated path physiological factors like hypercholesterolemia, hypertension, diabetes mellitus, and smoking actuates oxidative stress which are characterized by excessive oxidation and improper exclusion. The herbal plant-based antioxidant agents are effective towards the management/treatment of atherosclerosis by different ways like, by diminishing the oxidation of low-density lipoproteins, diminishing the cell proliferation, restraining the foam cell arrangement, and advancing the reverse cholesterol transport, down regulation of pro-atherogenic genes, and inflammatory mediators. This review is a critical analysis about the role of oxidative stress in atherogenesis and furthermore outlines the ongoing study/examination done on the management of atherosclerosis by utilizing herbal antioxidant agents.
PURPOSE OF REVIEW: Summarize of the reports on antioxidants especially from herbal sources which battle oxidative stress might be proficient to forestall and repair the free radical-prompted vascular damages in overseeing of atherosclerosis. RECENT FINDINGS:Atherosclerosis is the one of the fundamental reason for hypertension, stroke, myocardial localized necrosis, and numerous other cardiovascular illnesses. Atherosclerosis associated path physiological factors like hypercholesterolemia, hypertension, diabetes mellitus, and smoking actuates oxidative stress which are characterized by excessive oxidation and improper exclusion. The herbal plant-based antioxidant agents are effective towards the management/treatment of atherosclerosis by different ways like, by diminishing the oxidation of low-density lipoproteins, diminishing the cell proliferation, restraining the foam cell arrangement, and advancing the reverse cholesterol transport, down regulation of pro-atherogenic genes, and inflammatory mediators. This review is a critical analysis about the role of oxidative stress in atherogenesis and furthermore outlines the ongoing study/examination done on the management of atherosclerosis by utilizing herbal antioxidant agents.
Authors: Wendy L Zhang; Ken Y Z Zheng; Kevin Y Zhu; Janis Y X Zhan; Cathy W C Bi; J P Chen; Tina T X Dong; Roy C Y Choi; David T W Lau; Karl W K Tsim Journal: Evid Based Complement Alternat Med Date: 2013-02-05 Impact factor: 2.629
Authors: Javad Sharifi-Rad; Célia F Rodrigues; Farukh Sharopov; Anca Oana Docea; Aslı Can Karaca; Mehdi Sharifi-Rad; Derya Kahveci Karıncaoglu; Gözde Gülseren; Ezgi Şenol; Evren Demircan; Yasaman Taheri; Hafiz Ansar Rasul Suleria; Beraat Özçelik; Kadriye Nur Kasapoğlu; Mine Gültekin-Özgüven; Ceren Daşkaya-Dikmen; William C Cho; Natália Martins; Daniela Calina Journal: Int J Environ Res Public Health Date: 2020-03-30 Impact factor: 3.390