Literature DB >> 14722607

Bmi1, stem cells, and senescence regulation.

In-Kyung Park1, Sean J Morrison, Michael F Clarke.   

Abstract

Stem cells generate the differentiated cell types within many organs throughout the lifespan of an organism and are thus ultimately responsible for the longevity of multicellular organisms. Therefore, senescence of stem cells must be prevented. Bmi1 is required for the maintenance of adult stem cells in some tissues partly because it represses genes that induce cellular senescence and cell death.

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Year:  2004        PMID： 14722607      PMCID： PMC311443          DOI： 10.1172/JCI20800

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  58 in total

1.  Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.

Authors:  Anna V Molofsky; Ricardo Pardal; Toshihide Iwashita; In-Kyung Park; Michael F Clarke; Sean J Morrison
Journal:  Nature       Date:  2003-10-22       Impact factor: 49.962

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Journal:  Cell       Date:  1992-12-11       Impact factor: 41.582

Review 3.  Genetic control of stem-cell properties and stem cells in aging.

Authors:  Ying Liang; Gary Van Zant
Journal:  Curr Opin Hematol       Date:  2003-05       Impact factor: 3.284

Review 4.  Senescence, apoptosis and therapy--cutting the lifelines of cancer.

Authors:  Clemens A Schmitt
Journal:  Nat Rev Cancer       Date:  2003-04       Impact factor: 60.716

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Authors:  A A Davis; S Temple
Journal:  Nature       Date:  1994-11-17       Impact factor: 49.962

6.  Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest.

Authors:  D E Quelle; F Zindy; R A Ashmun; C J Sherr
Journal:  Cell       Date:  1995-12-15       Impact factor: 41.582

7.  Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice.

Authors:  Michael TeKippe; David E Harrison; Jichun Chen
Journal:  Exp Hematol       Date:  2003-06       Impact factor: 3.084

8.  Purification and characterization of mouse hematopoietic stem cells.

Authors:  G J Spangrude; S Heimfeld; I L Weissman
Journal:  Science       Date:  1988-07-01       Impact factor: 47.728

9.  Major age-related changes of mouse hematopoietic stem/progenitor cells.

Authors:  Mijung Kim; Hee-Bom Moon; Gerald J Spangrude
Journal:  Ann N Y Acad Sci       Date:  2003-05       Impact factor: 5.691

10.  Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.

Authors:  Masashi Narita; Sabrina Nũnez; Edith Heard; Masako Narita; Athena W Lin; Stephen A Hearn; David L Spector; Gregory J Hannon; Scott W Lowe
Journal:  Cell       Date:  2003-06-13       Impact factor: 41.582
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  202 in total

Review 1.  The biology of head and neck cancer stem cells.

Authors:  Zhaocheng Zhang; Manoel Sant'Ana Filho; Jacques E Nör
Journal:  Oral Oncol       Date:  2011-11-08       Impact factor: 5.337

Review 2.  Do tumor-suppressive mechanisms contribute to organism aging by inducing stem cell senescence?

Authors:  Pier Giuseppe Pelicci
Journal:  J Clin Invest       Date:  2004-01       Impact factor: 14.808

3.  Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.

Authors:  Eunjeong Seo; Upal Basu-Roy; Jiri Zavadil; Claudio Basilico; Alka Mansukhani
Journal:  Mol Cell Biol       Date:  2011-09-19       Impact factor: 4.272

4.  Tumorigenesis: Twist1 links EMT to self-renewal.

Authors:  Alberto Martin; Amparo Cano
Journal:  Nat Cell Biol       Date:  2010-10       Impact factor: 28.824

5.  A Drosophila chromatin factor interacts with the Piwi-interacting RNA mechanism in niche cells to regulate germline stem cell self-renewal.

Authors:  Tora K Smulders-Srinivasan; Akos Szakmary; Haifan Lin
Journal:  Genetics       Date:  2010-07-20       Impact factor: 4.562

6.  Bmi1 Regulates the Proliferation of Cochlear Supporting Cells Via the Canonical Wnt Signaling Pathway.

Authors:  Xiaoling Lu; Shan Sun; Jieyu Qi; Wenyan Li; Liman Liu; Yanping Zhang; Yan Chen; Shasha Zhang; Lei Wang; Dengshun Miao; Renjie Chai; Huawei Li
Journal:  Mol Neurobiol       Date:  2016-02-03       Impact factor: 5.590

7.  Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype.

Authors:  Zhaocheng Zhang; Zhihong Dong; Isabel S Lauxen; Manoel Sant'Ana Filho; Jacques E Nör
Journal:  Cancer Res       Date:  2014-03-31       Impact factor: 12.701

8.  Nfatc1 orchestrates aging in hair follicle stem cells.

Authors:  Brice E Keyes; Jeremy P Segal; Evan Heller; Wen-Hui Lien; Chiung-Ying Chang; Xingyi Guo; Dan S Oristian; Deyou Zheng; Elaine Fuchs
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-26       Impact factor: 11.205

Review 9.  Novel ablation methods for treatment of gliomas.

Authors:  Brittanie Partridge; John H Rossmeisl; Alexandra M Kaloss; Erwin Kristobal Gudenschwager Basso; Michelle H Theus
Journal:  J Neurosci Methods       Date:  2020-02-14       Impact factor: 2.390

10.  p63 deficiency activates a program of cellular senescence and leads to accelerated aging.

Authors:  William M Keyes; Ying Wu; Hannes Vogel; Xuecui Guo; Scott W Lowe; Alea A Mills
Journal:  Genes Dev       Date:  2005-08-17       Impact factor: 11.361
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