Literature DB >> 20885418

Tumorigenesis: Twist1 links EMT to self-renewal.

Alberto Martin, Amparo Cano.   

Abstract

The epithelial-mesenchymal transition (EMT) occurs in pre-metastatic cancer cells and is also associated with the acquisition of stem-cell-like characteristics. A molecular link between EMT and stemness now emerges with the finding that Bmi1, a polycomb protein that promotes self-renewal of certain stem-cell populations, is a direct transcriptional target of the EMT inducer, Twist1.

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Year:  2010        PMID： 20885418     DOI： 10.1038/ncb1010-924

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  14 in total

Review 1.  Bmi1, stem cells, and senescence regulation.

Authors:  In-Kyung Park; Sean J Morrison; Michael F Clarke
Journal:  J Clin Invest       Date:  2004-01       Impact factor: 14.808

2.  Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.

Authors:  Payman Samavarchi-Tehrani; Azadeh Golipour; Laurent David; Hoon-Ki Sung; Tobias A Beyer; Alessandro Datti; Knut Woltjen; Andras Nagy; Jeffrey L Wrana
Journal:  Cell Stem Cell       Date:  2010-06-17       Impact factor: 24.633

3.  A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts.

Authors:  Ronghui Li; Jialiang Liang; Su Ni; Ting Zhou; Xiaobing Qing; Huapeng Li; Wenzhi He; Jiekai Chen; Feng Li; Qiang Zhuang; Baoming Qin; Jianyong Xu; Wen Li; Jiayin Yang; Yi Gan; Dajiang Qin; Shipeng Feng; Hong Song; Dongshan Yang; Biliang Zhang; Lingwen Zeng; Liangxue Lai; Miguel Angel Esteban; Duanqing Pei
Journal:  Cell Stem Cell       Date:  2010-06-17       Impact factor: 24.633

Review 4.  Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition.

Authors:  Amparo Cano; M Angela Nieto
Journal:  Trends Cell Biol       Date:  2008-06-26       Impact factor: 20.808

Review 5.  Cancer stem cells: mirage or reality?

Authors:  Piyush B Gupta; Christine L Chaffer; Robert A Weinberg
Journal:  Nat Med       Date:  2009-09-04       Impact factor: 53.440

Review 6.  Epithelial-mesenchymal transitions in development and disease.

Authors:  Jean Paul Thiery; Hervé Acloque; Ruby Y J Huang; M Angela Nieto
Journal:  Cell       Date:  2009-11-25       Impact factor: 41.582

Review 7.  Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression.

Authors:  Thomas Brabletz; Andreas Jung; Simone Spaderna; Falk Hlubek; Thomas Kirchner
Journal:  Nat Rev Cancer       Date:  2005-09       Impact factor: 60.716

8.  Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition.

Authors:  Muh-Hwa Yang; Dennis Shin-Shian Hsu; Hsei-Wei Wang; Hsiao-Jung Wang; Hsin-Yi Lan; Wen-Hao Yang; Chi-Hung Huang; Shou-Yen Kao; Cheng-Hwai Tzeng; Shyh-Kuan Tai; Shyue-Yih Chang; Oscar Kuang-Sheng Lee; Kou-Juey Wu
Journal:  Nat Cell Biol       Date:  2010-09-05       Impact factor: 28.824

9.  The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

Authors:  Ulrich Wellner; Jörg Schubert; Ulrike C Burk; Otto Schmalhofer; Feng Zhu; Annika Sonntag; Bettina Waldvogel; Corinne Vannier; Douglas Darling; Axel zur Hausen; Valerie G Brunton; Jennifer Morton; Owen Sansom; Julia Schüler; Marc P Stemmler; Christoph Herzberger; Ulrich Hopt; Tobias Keck; Simone Brabletz; Thomas Brabletz
Journal:  Nat Cell Biol       Date:  2009-11-22       Impact factor: 28.824

10.  The epithelial-mesenchymal transition generates cells with properties of stem cells.

Authors:  Sendurai A Mani; Wenjun Guo; Mai-Jing Liao; Elinor Ng Eaton; Ayyakkannu Ayyanan; Alicia Y Zhou; Mary Brooks; Ferenc Reinhard; Cheng Cheng Zhang; Michail Shipitsin; Lauren L Campbell; Kornelia Polyak; Cathrin Brisken; Jing Yang; Robert A Weinberg
Journal:  Cell       Date:  2008-05-16       Impact factor: 41.582
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  49 in total

Review 1.  Regulation of stem cell plasticity: mechanisms and relevance to tissue biology and cancer.

Authors:  Robert Strauss; Petra Hamerlik; André Lieber; Jiri Bartek
Journal:  Mol Ther       Date:  2012-02-07       Impact factor: 11.454

2.  Perspectives of gene combinations in phenotype presentation.

Authors:  Shihori Tanabe
Journal:  World J Stem Cells       Date:  2013-07-26       Impact factor: 5.326

Review 3.  The epigenetics of epithelial-mesenchymal plasticity in cancer.

Authors:  Wai Leong Tam; Robert A Weinberg
Journal:  Nat Med       Date:  2013-11-07       Impact factor: 53.440

4.  HOXB5 promotes malignant progression in pancreatic cancer via the miR-6732 pathway.

Authors:  Zhi-Xi Li; Gang Wu; Wen-Jun Jiang; Jie Li; You-Yu Wang; Xue-Ming Ju; Yan-Tao Yin
Journal:  Cell Cycle       Date:  2019-12-26       Impact factor: 4.534

5.  Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells.

Authors:  Mingli Han; Manran Liu; Yimeng Wang; Zhiqiang Mo; Xiaokai Bi; Zhirong Liu; Yuanming Fan; Xin Chen; Chengyi Wu
Journal:  Mol Cell Biochem       Date:  2011-12-21       Impact factor: 3.396

6.  Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions.

Authors:  Alejandro Vazquez-Martin; Eugeni López-Bonetc; Sílvia Cufí; Cristina Oliveras-Ferraros; Sonia Del Barco; Begoña Martin-Castillo; Javier A Menendez
Journal:  Drug Resist Updat       Date:  2011-05-19       Impact factor: 18.500

7.  IL-1β promotes proliferation and migration of gallbladder cancer cells via Twist activation.

Authors:  Runsheng Guo; Yiyu Qin; Peidong Shi; Jinbi Xie; Ming Chou; Yueyu Chen
Journal:  Oncol Lett       Date:  2016-10-13       Impact factor: 2.967

Review 8.  Cancer stem cells, epithelial-mesenchymal transition, and drug resistance in high-grade ovarian serous carcinoma.

Authors:  Xiaoxiang Chen; Jing Zhang; Zhihong Zhang; Hongxia Li; Wenjun Cheng; Jinsong Liu
Journal:  Hum Pathol       Date:  2013-07-11       Impact factor: 3.466

Review 9.  Pancreatic cancer stem cell markers and exosomes - the incentive push.

Authors:  Sarah Heiler; Zhe Wang; Margot Zöller
Journal:  World J Gastroenterol       Date:  2016-07-14       Impact factor: 5.742

10.  MAML1 promotes ESCC aggressiveness through upregulation of EMT marker TWIST1.

Authors:  Mohammad Mahdi Forghanifard; Shirin Azaraz; Sima Ardalan Khales; Dorsa Morshedi Rad; Mohammad Reza Abbaszadegan
Journal:  Mol Biol Rep       Date:  2020-03-16       Impact factor: 2.316
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