| Literature DB >> 14697775 |
Tatiana Fonseca1, Bárbara Gigante, M Matilde Marques, Thomas L Gilchrist, Erik De Clercq.
Abstract
Several heterocycles, such as benzimidazoles, quinoxalines and indoles incorporated into a hydrophenanthrene and naphthalene skeleton, were synthesised from two useful ortho-bromonitro precursors derived from dehydroabietic acid: methyl 12-bromo-13-nitro-deisopropyldehydroabietate and methyl 12-bromo-13,14-dinitro-deisopropyldehydroabietate. The new heterocycles were evaluated for their activity in vitro against several RNA and DNA viruses.Entities:
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Year: 2004 PMID： 14697775 DOI： 10.1016/j.bmc.2003.10.013
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641