Literature DB >> 14691643

Predictive genetic testing in urology: ethical and social issues.

Maxwell J Mehlman1.   

Abstract

In order to maximize the benefits of predictive genetic testing in urology, the potential ethical and social risks must be identified and minimized. Necessary steps include providing adequate information for patients and families; preparing them to receive test results; maintaining confidentiality to avoid social stigma and discrimination; preserving the principal of solidarity to provide assurances of medical care and social support for persons at risk of genetic illness; and avoiding inappropriate social pressure to prevent the birth of at-risk individuals. Health professionals must play a significant role in helping individuals, families, and society in general to make sound testing decisions and policy.

Entities:  

Keywords:  Genetics and Reproduction

Mesh:

Year:  2003        PMID: 14691643     DOI: 10.1007/s00345-003-0376-6

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  9 in total

1.  Promoting safe and effective genetic testing in the United States. Final report of the Task Force on Genetic Testing.

Authors:  N A Holtzman; M S Watson
Journal:  J Child Fam Nurs       Date:  1999 Sep-Oct

2.  Neonatal screening varies by state of birth.

Authors:  M Mitka
Journal:  JAMA       Date:  2000-10-25       Impact factor: 56.272

3.  Boom in gene testing raises questions on sharing results.

Authors:  T Lewin
Journal:  N Y Times Web       Date:  2000-07-21

4.  Prenatal screening and the culture of motherhood.

Authors:  Lori B Andrews
Journal:  Hastings Law J       Date:  1996-04

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Authors:  H T Greely
Journal:  Houst Law Rev       Date:  1997

6.  ASHG statement. Professional disclosure of familial genetic information. The American Society of Human Genetics Social Issues Subcommittee on Familial Disclosure.

Authors: 
Journal:  Am J Hum Genet       Date:  1998-02       Impact factor: 11.025

Review 7.  The family covenant and genetic testing.

Authors:  D J Doukas; J W Berg
Journal:  Am J Bioeth       Date:  2001       Impact factor: 11.229

8.  Predictive testing for Huntington disease in Canada: adverse effects and unexpected results in those receiving a decreased risk.

Authors:  M Huggins; M Bloch; S Wiggins; S Adam; O Suchowersky; M Trew; M Klimek; C R Greenberg; M Eleff; L P Thompson
Journal:  Am J Med Genet       Date:  1992-02-15

9.  Predictive testing for Huntington disease in Canada: the experience of those receiving an increased risk.

Authors:  M Bloch; S Adam; S Wiggins; M Huggins; M R Hayden
Journal:  Am J Med Genet       Date:  1992-02-15
  9 in total
  4 in total

1.  Reporting genetic results in research studies: summary and recommendations of an NHLBI working group.

Authors:  Ebony B Bookman; Aleisha A Langehorne; John H Eckfeldt; Kathleen C Glass; Gail P Jarvik; Michael Klag; Greg Koski; Arno Motulsky; Benjamin Wilfond; Teri A Manolio; Richard R Fabsitz; Russell V Luepker
Journal:  Am J Med Genet A       Date:  2006-05-15       Impact factor: 2.802

Review 2.  Screening for bladder cancer: a perspective.

Authors:  Yair Lotan; Robert S Svatek; Núria Malats
Journal:  World J Urol       Date:  2007-11-21       Impact factor: 4.226

3.  Incidental genetic findings in randomized clinical trials: recommendations from the Genomics and Randomized Trials Network (GARNET).

Authors:  Ebony B Bookman; Corina Din-Lovinescu; Bradford B Worrall; Teri A Manolio; Siiri N Bennett; Cathy Laurie; Daniel B Mirel; Kimberly F Doheny; Garnet L Anderson; Kate Wehr; Richard Weinshilboum; Donna T Chen
Journal:  Genome Med       Date:  2013-01-30       Impact factor: 11.117

4.  An update to returning genetic research results to individuals: perspectives of the industry pharmacogenomics working group.

Authors:  Sandra K Prucka; Lester J Arnold; John E Brandt; Sandra Gilardi; Lea C Harty; Feng Hong; Joanne Malia; David J Pulford
Journal:  Bioethics       Date:  2014-01-29       Impact factor: 1.898

  4 in total

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