Literature DB >> 14624719

GenomEUtwin: a strategy to identify genetic influences on health and disease.

Leena Peltonen1.   

Abstract

In this issue of Twin Research, we describe different facets of a European Community funded effort, GenomEUtwin, which capitalises on eight of the world's largest and best characterised twin registers and a multi-national population cohort, MORGAM. This international study, reaching beyond the geographical borders of Europe, is based on linkage and association strategies designed to identify genetic contributors to health and disease using integrated expertise of participating groups in genetics, epidemiology and biostatistics. By merging information from numerous epidemiological and genetic databases, GenomEUtwin will create an intellectual and technical infrastructure for future genetic epidemiological studies aiming to define genetic and life style risks for common human diseases.

Entities:  

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Year:  2003        PMID： 14624719     DOI： 10.1375/136905203770326358

Source DB:  PubMed          Journal:  Twin Res        ISSN： 1369-0523


  13 in total

1.  The feasibility of creating a population-based national twin registry in the United States.

Authors:  Patricia C Chulada; Linda A Corey; Vani Vannappagari; Nedra S Whitehead; Perry J Blackshear
Journal:  Twin Res Hum Genet       Date:  2006-12       Impact factor: 1.587

2.  Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels.

Authors:  Beben Benyamin; Allan F McRae; Gu Zhu; Scott Gordon; Anjali K Henders; Aarno Palotie; Leena Peltonen; Nicholas G Martin; Grant W Montgomery; John B Whitfield; Peter M Visscher
Journal:  Am J Hum Genet       Date:  2008-12-11       Impact factor: 11.025

3.  Genome-wide association study of smoking initiation and current smoking.

Authors:  Jacqueline M Vink; August B Smit; Eco J C de Geus; Patrick Sullivan; Gonneke Willemsen; Jouke-Jan Hottenga; Johannes H Smit; Witte J Hoogendijk; Frans G Zitman; Leena Peltonen; Jaakko Kaprio; Nancy L Pedersen; Patrik K Magnusson; Tim D Spector; Kirsten Ohm Kyvik; Katherine I Morley; Andrew C Heath; Nicholas G Martin; Rudi G J Westendorp; P Eline Slagboom; Henning Tiemeier; Albert Hofman; Andre G Uitterlinden; Yurii S Aulchenko; Najaf Amin; Cornelia van Duijn; Brenda W Penninx; Dorret I Boomsma
Journal:  Am J Hum Genet       Date:  2009-03-05       Impact factor: 11.025

4.  Geographical structure and differential natural selection among North European populations.

Authors:  Brian P McEvoy; Grant W Montgomery; Allan F McRae; Samuli Ripatti; Markus Perola; Tim D Spector; Lynn Cherkas; Kourosh R Ahmadi; Dorret Boomsma; Gonneke Willemsen; Jouke J Hottenga; Nancy L Pedersen; Patrik K E Magnusson; Kirsten Ohm Kyvik; Kaare Christensen; Jaakko Kaprio; Kauko Heikkilä; Aarno Palotie; Elisabeth Widen; Juha Muilu; Ann-Christine Syvänen; Ulrika Liljedahl; Orla Hardiman; Simon Cronin; Leena Peltonen; Nicholas G Martin; Peter M Visscher
Journal:  Genome Res       Date:  2009-03-05       Impact factor: 9.043

5.  Genetic variants near PDGFRA are associated with corneal curvature in Australians.

Authors:  Aniket Mishra; Seyhan Yazar; Alex W Hewitt; Jenny A Mountain; Wei Ang; Craig E Pennell; Nicholas G Martin; Grant W Montgomery; Christopher J Hammond; Terri L Young; Stuart Macgregor; David A Mackey
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-10-11       Impact factor: 4.799

Review 6.  The continuing value of twin studies in the omics era.

Authors:  Jenny van Dongen; P Eline Slagboom; Harmen H M Draisma; Nicholas G Martin; Dorret I Boomsma
Journal:  Nat Rev Genet       Date:  2012-07-31       Impact factor: 53.242

7.  Migraine genetics: current findings and future lines of research.

Authors:  A M Persico; M Verdecchia; V Pinzone; V Guidetti
Journal:  Neurogenetics       Date:  2014-12-14       Impact factor: 2.660

8.  A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol.

Authors:  Ida Surakka; John B Whitfield; Markus Perola; Peter M Visscher; Grant W Montgomery; Mario Falchi; Gonneke Willemsen; Eco J C de Geus; Patrik K E Magnusson; Kaare Christensen; Thorkild I A Sørensen; Kirsi H Pietiläinen; Taina Rantanen; Kaisa Silander; Elisabeth Widén; Juha Muilu; Iffat Rahman; Ulrika Liljedahl; Ann-Christine Syvänen; Aarno Palotie; Jaakko Kaprio; Kirsten O Kyvik; Nancy L Pedersen; Dorret I Boomsma; Tim Spector; Nicholas G Martin; Samuli Ripatti; Leena Peltonen
Journal:  Twin Res Hum Genet       Date:  2012-10-03       Impact factor: 1.587

9.  Analysis of twin data using SAS.

Authors:  Rui Feng; Gongfu Zhou; Meizhuo Zhang; Heping Zhang
Journal:  Biometrics       Date:  2008-07-18       Impact factor: 2.571

10.  Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

Authors:  Yurii S Aulchenko; Samuli Ripatti; Ida Lindqvist; Dorret Boomsma; Iris M Heid; Peter P Pramstaller; Brenda W J H Penninx; A Cecile J W Janssens; James F Wilson; Tim Spector; Nicholas G Martin; Nancy L Pedersen; Kirsten Ohm Kyvik; Jaakko Kaprio; Albert Hofman; Nelson B Freimer; Marjo-Riitta Jarvelin; Ulf Gyllensten; Harry Campbell; Igor Rudan; Asa Johansson; Fabio Marroni; Caroline Hayward; Veronique Vitart; Inger Jonasson; Cristian Pattaro; Alan Wright; Nick Hastie; Irene Pichler; Andrew A Hicks; Mario Falchi; Gonneke Willemsen; Jouke-Jan Hottenga; Eco J C de Geus; Grant W Montgomery; John Whitfield; Patrik Magnusson; Juha Saharinen; Markus Perola; Kaisa Silander; Aaron Isaacs; Eric J G Sijbrands; Andre G Uitterlinden; Jacqueline C M Witteman; Ben A Oostra; Paul Elliott; Aimo Ruokonen; Chiara Sabatti; Christian Gieger; Thomas Meitinger; Florian Kronenberg; Angela Döring; H-Erich Wichmann; Johannes H Smit; Mark I McCarthy; Cornelia M van Duijn; Leena Peltonen
Journal:  Nat Genet       Date:  2008-12-07       Impact factor: 38.330
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