Literature DB >> 14563884

A transcriptional pause synchronizes translation with transcription in the tryptophanase operon leader region.

Feng Gong1, Charles Yanofsky.   

Abstract

Regulation of transcription of the tryptophanase operon requires that translation of its leader peptide coding region, tnaC, be coupled with its transcription. We show in vitro that a transcription pause site exists at the end of the tnaC coding region and that translation of tnaC releases the paused transcription complex, coupling transcription with translation.

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Year:  2003        PMID： 14563884      PMCID： PMC219409          DOI： 10.1128/JB.185.21.6472-6476.2003

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  19 in total

1.  Analysis of tryptophanase operon expression in vitro: accumulation of TnaC-peptidyl-tRNA in a release factor 2-depleted S-30 extract prevents Rho factor action, simulating induction.

Authors:  Feng Gong; Charles Yanofsky
Journal:  J Biol Chem       Date:  2002-03-05       Impact factor: 5.157

Review 2.  Rho-dependent termination and ATPases in transcript termination.

Authors:  John P Richardson
Journal:  Biochim Biophys Acta       Date:  2002-09-13

3.  A contribution to the chemistry of proteids: Part II. The constitution of tryptophane, and the action of bacteria upon it.

Authors:  F G Hopkins; S W Cole
Journal:  J Physiol       Date:  1903-06-15       Impact factor: 5.182

4.  Indole can act as an extracellular signal in Escherichia coli.

Authors:  D Wang; X Ding; P N Rather
Journal:  J Bacteriol       Date:  2001-07       Impact factor: 3.490

5.  Nucleotide sequence of the structural gene for tryptophanase of Escherichia coli K-12.

Authors:  M C Deeley; C Yanofsky
Journal:  J Bacteriol       Date:  1981-09       Impact factor: 3.490

6.  Identifying the bicyclomycin binding domain through biochemical analysis of antibiotic-resistant rho proteins.

Authors:  A Magyar; X Zhang; F Abdi; H Kohn; W R Widger
Journal:  J Biol Chem       Date:  1999-03-12       Impact factor: 5.157

7.  NusA-stimulated RNA polymerase pausing and termination participates in the Bacillus subtilis trp operon attenuation mechanism invitro.

Authors:  Alexander V Yakhnin; Paul Babitzke
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-02       Impact factor: 11.205

8.  Instruction of translating ribosome by nascent peptide.

Authors:  Feng Gong; Charles Yanofsky
Journal:  Science       Date:  2002-09-13       Impact factor: 47.728

9.  tRNA(Trp) translation of leader peptide codon 12 and other factors that regulate expression of the tryptophanase operon.

Authors:  P Gollnick; C Yanofsky
Journal:  J Bacteriol       Date:  1990-06       Impact factor: 3.490

10.  Translation activates the paused transcription complex and restores transcription of the trp operon leader region.

Authors:  R Landick; J Carey; C Yanofsky
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205
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  9 in total

1.  Kinetic analysis of tRNA-directed transcription antitermination of the Bacillus subtilis glyQS gene in vitro.

Authors:  Frank J Grundy; Tina M Henkin
Journal:  J Bacteriol       Date:  2004-08       Impact factor: 3.490

2.  Evidence for moonlighting functions of the θ subunit of Escherichia coli DNA polymerase III.

Authors:  M Dietrich; L Pedró; J García; M Pons; M Hüttener; S Paytubi; C Madrid; A Juárez
Journal:  J Bacteriol       Date:  2013-12-27       Impact factor: 3.490

Review 3.  The ribosome: a metabolite-responsive transcription regulator.

Authors:  Valley Stewart
Journal:  J Bacteriol       Date:  2008-05-16       Impact factor: 3.490

4.  Recognition of the regulatory nascent chain TnaC by the ribosome.

Authors:  Leonardo G Trabuco; Christopher B Harrison; Eduard Schreiner; Klaus Schulten
Journal:  Structure       Date:  2010-05-12       Impact factor: 5.006

5.  Tryptophan inhibits Proteus vulgaris TnaC leader peptide elongation, activating tna operon expression.

Authors:  Luis R Cruz-Vera; Rui Yang; Charles Yanofsky
Journal:  J Bacteriol       Date:  2009-09-18       Impact factor: 3.490

6.  Factor-independent transcription pausing caused by recognition of the RNA-DNA hybrid sequence.

Authors:  Aleksandra Bochkareva; Yulia Yuzenkova; Vasisht R Tadigotla; Nikolay Zenkin
Journal:  EMBO J       Date:  2011-11-29       Impact factor: 11.598

7.  Folding pathway of an Ig domain is conserved on and off the ribosome.

Authors:  Pengfei Tian; Annette Steward; Renuka Kudva; Ting Su; Patrick J Shilling; Adrian A Nickson; Jeffrey J Hollins; Roland Beckmann; Gunnar von Heijne; Jane Clarke; Robert B Best
Journal:  Proc Natl Acad Sci U S A       Date:  2018-11-09       Impact factor: 11.205

8.  Tryptophan Metabolism by Gut Microbiome and Gut-Brain-Axis: An in silico Analysis.

Authors:  Harrisham Kaur; Chandrani Bose; Sharmila S Mande
Journal:  Front Neurosci       Date:  2019-12-18       Impact factor: 4.677

9.  Non-Invasive Analysis of Recombinant mRNA Stability in Escherichia coli by a Combination of Transcriptional Inducer Wash-Out and qRT-PCR.

Authors:  Veronika Kucharova; Trine Aakvik Strand; Eivind Almaas; Adrian E Naas; Trygve Brautaset; Svein Valla
Journal:  PLoS One       Date:  2013-06-19       Impact factor: 3.240
  9 in total

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