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Literature DB >> 13959526

Physicochemical studies on the reaction between formaldehyde and DNA.

Abstract

The reaction between formaldehyde and phage T7 DNA has been studied by optical absorbance and sedimentation measurements. Through the course of denaturation, OD(200) and s(20, w) rise; after the attainment of full hyperchromicity the s(20, w) falls sharply, suggesting a decrease in molecular weight. Conditions in which formaldehyde causes cross-linking are defined. Some experimental applications of the denaturation technique are given. Evidence which suggests that preformed single-strand interruptions may exist in phage DNA is briefly discussed.

Entities: Chemical Species

Keywords: COLIPHAGES; DNA, VIRAL; FORMALDEHYDE

Mesh：

Substances：

Year: 1963 PMID： 13959526 PMCID： PMC1366423 DOI： 10.1016/s0006-3495(63)86803-4

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

15 in total

1. The reaction of formaldehyde with denatured DNA: spectrophotometric, immunologic, and enzymic studies.

Authors: D STOLLAR; L GROSSMAN
Journal: J Mol Biol Date: 1962-01 Impact factor: 5.469

2. Nonaqueous solutions of DNA. Reversible and irreversible denaturation in methanol.

Authors: E P GEIDUSCHEK; T T HERSKOVITS
Journal: Arch Biochem Biophys Date: 1961-10 Impact factor: 4.013

3. On the factors controlling the reversibility of DNA denaturation.

Authors: E P GEIDUSCHEK
Journal: J Mol Biol Date: 1962-06 Impact factor: 5.469

4. Studies on the sonic degradation of deoxyribonucleic acid.

Authors: D FREIFELDER; P F DAVISON
Journal: Biophys J Date: 1962-05 Impact factor: 4.033

5. The reaction of formaldehyde with polynucleotides.

Authors: R HASELKORN; P DOTY
Journal: J Biol Chem Date: 1961-10 Impact factor: 5.157

6. The thermal degradation of nucleic acids.

Authors: J EIGNER; H BOEDTKER; G MICHAELS
Journal: Biochim Biophys Acta Date: 1961-07-22

7. The reaction of formaldehyde with nucleotides and T2 bacteriophage DNA.

Authors: L GROSSMAN; S S LEVINE; W S ALLISON
Journal: J Mol Biol Date: 1961-02 Impact factor: 5.469

8. Chromosome brekage accompanying genetic recombination in bacteriophage.

Authors: M MESELSON; J J WEIGLE
Journal: Proc Natl Acad Sci U S A Date: 1961-06-15 Impact factor: 11.205

9. A new method for the isolation of deoxyribonucleic acids; evidence on the nature of bonds between deoxyribonucleic acid and protein.

Authors: K S KIRBY
Journal: Biochem J Date: 1957-07 Impact factor: 3.857

10. The Molecular Weight and Aggregation of DNA.

Authors: L F Cavalieri; J F Deutsch; B H Rosenberg
Journal: Biophys J Date: 1961-03 Impact factor: 4.033

22 in total

1. ENERGY REQUIREMENT FOR THYMINELESS DEATH IN CELLS OF ESCHERICHIA COLI.

Authors: D FREIFELDER; O MAALOE
Journal: J Bacteriol Date: 1964-10 Impact factor: 3.490

2. EVIDENCE FOR A RING STRUCTURE OF POLYOMA VIRUS DNA.

Authors: R DULBECCO; M VOGT
Journal: Proc Natl Acad Sci U S A Date: 1963-08 Impact factor: 11.205

3. THE CYCLIC HELIX AND CYCLIC COIL FORMS OF POLYOMA VIRAL DNA.

Authors: R WEIL; J VINOGRAD
Journal: Proc Natl Acad Sci U S A Date: 1963-10 Impact factor: 11.205

4. Letters to the editor.

Authors: D FREIFELDER; P F DAVISON
Journal: Biophys J Date: 1963-01 Impact factor: 4.033

5. A structural model for the genome of echovirus 22.

Authors: L A Seal; R M Jamison
Journal: Arch Virol Date: 1990 Impact factor: 2.574

6. Force-induced structural transitions in cross-linked DNA films.

Authors: A André; F Fontaine-Vive; H M Möller; T Fischer; G Maret; V T Forsyth; T Gisler
Journal: Eur Biophys J Date: 2008-01-31 Impact factor: 1.733

7. The molecular basis for biological inactivation of nucleic acids. The action of methylating agents on the ribonucleic acid-containing bacteriophage R17.

Authors: K V Shooter; R Howse; S A Shah; P D Lawley
Journal: Biochem J Date: 1974-02 Impact factor: 3.857

8. Studies on Escherichia coli sex factors: evidence that covalent circles exist within cells and the general problem of isolation of covalent circles.

Authors: D Freifelder; A Folkmanis; I Kirschner
Journal: J Bacteriol Date: 1971-03 Impact factor: 3.490

9. Repair of DNA studied with a nuclease specific for UV-induced lesions.

Authors: B Strauss; T Searashi; M Robbins
Journal: Proc Natl Acad Sci U S A Date: 1966-09 Impact factor: 11.205

10. Physical properties of the DNA of bacteriophage SP50.

Authors: N Biswal; A K Kleinschmidt; H C Spatz; T A Trautner
Journal: Mol Gen Genet Date: 1967