Literature DB >> 1392956

Time delays in provision of thrombolytic treatment in six district hospitals. Joint Audit Committee of the British Cardiac Society and a Cardiology Committee of Royal College of Physicians of London.

J S Birkhead1.   

Abstract

OBJECTIVE: To measure the delays between onset of symptoms and admission to hospital and provision of thrombolysis in patients with possible acute myocardial infarction.
DESIGN: Observational study of patients admitted with suspected myocardial infarction during six months.
SETTING: Six district general hospitals in Britain.
SUBJECTS: 1934 patients admitted with suspected myocardial infarction. MAIN OUTCOME MEASURES: Route of admission to hospital and time to admission and thrombolysis.
RESULTS: Patients who made emergency calls did so sooner after onset of symptoms than those who called their doctor (median time 40 (95% confidence interval 30 to 52) minutes v 70 (60 to 90) minutes). General practitioners took a median of 20 (20 to 25) minutes to visit patients, rising to 30 (20 to 30) minutes during 0800-1200. The median time from call to arrival in hospital was 41 (38 to 47) minutes for patients who called an ambulance from home and 90 (90 to 94) minutes for those who contacted their doctor. The median time from arrival at hospital to thrombolysis was 80 (75 to 85) minutes for patients who were treated in the cardiac care unit and 31 (25 to 35) minutes for those treated in the accident and emergency department.
CONCLUSION: The time from onset of symptoms to thrombolysis could be reduced substantially by more effective use of emergency services and faster provision of thrombolysis in accident and emergency departments.

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Year:  1992        PMID: 1392956      PMCID: PMC1882547          DOI: 10.1136/bmj.305.6851.445

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  13 in total

1.  Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction. Anglo-Scandinavian Study of Early Thrombolysis (ASSET).

Authors:  R G Wilcox; G von der Lippe; C G Olsson; G Jensen; A M Skene; J R Hampton
Journal:  Lancet       Date:  1988-09-03       Impact factor: 79.321

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Authors:  A Colling; A W Dellipiani; R J Donaldson; P MacCormack
Journal:  Br Med J       Date:  1976-11-13

3.  An audit of doctor's management of patients with chest pain in the accident and emergency department.

Authors:  P A Emerson; N J Russell; J Wyatt; N Crichton; C F Pantin; A D Morgan; P R Fleming
Journal:  Q J Med       Date:  1989-03

4.  Time delays in the diagnosis and treatment of acute myocardial infarction: a tale of eight cities. Report from the Pre-hospital Study Group and the Cincinnati Heart Project.

Authors:  D J Kereiakes; W D Weaver; J L Anderson; T Feldman; B Gibler; T Aufderheide; D O Williams; L H Martin; L C Anderson; J S Martin
Journal:  Am Heart J       Date:  1990-10       Impact factor: 4.749

5.  The prehospital course of patients with chest pain. Analysis of the prodromal, symptomatic, decision-making, transportation and emergency room periods.

Authors:  J S Schroeder; I H Lamb; M Hu
Journal:  Am J Med       Date:  1978-05       Impact factor: 4.965

6.  An analysis of time delays preceding thrombolysis for acute myocardial infarction.

Authors:  S W Sharkey; D D Bruneete; E Ruiz; W T Hession; D G Wysham; I F Goldenberg; M Hodges
Journal:  JAMA       Date:  1989-12-08       Impact factor: 56.272

7.  Prevention of myocardial damage in acute myocardial ischemia by early treatment with intravenous streptokinase.

Authors:  G Koren; A T Weiss; Y Hasin; D Appelbaum; S Welber; Y Rozenman; C Lotan; M Mosseri; D Sapoznikov; M H Luria
Journal:  N Engl J Med       Date:  1985-11-28       Impact factor: 91.245

8.  Follow-up of emergency ambulance calls in Nottingham: implications for coronary ambulance servie.

Authors:  M Cameron; F Wilkinson; J R Hampton
Journal:  Br Med J       Date:  1975-02-15

9.  Effect of "fast track" admission for acute myocardial infarction on delay to thrombolysis.

Authors:  A C Pell; H C Miller; C E Robertson; K A Fox
Journal:  BMJ       Date:  1992-01-11

10.  Association of patient delay with symptoms, cardiac enzymes, and outcome in acute myocardial infarction.

Authors:  J M Rawles; M J Metcalfe; C Shirreffs; K Jennings; A C Kenmure
Journal:  Eur Heart J       Date:  1990-07       Impact factor: 29.983

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  43 in total

1.  Recognition of ST elevation by paramedics.

Authors:  M Whitbread; V Leah; T Bell; T J Coats
Journal:  Emerg Med J       Date:  2002-01       Impact factor: 2.740

2.  Delays in thrombolysis.

Authors:  P Watson
Journal:  BMJ       Date:  1992-10-03

3.  Domiciliary thrombolysis by general practitioners.

Authors:  P H Seidelin; B D Vallance
Journal:  BMJ       Date:  1992-11-21

Review 4.  Cost implications of prehospital emergency drug administration. The case of prehospital thrombolytics.

Authors:  S Barton; T Walley
Journal:  Pharmacoeconomics       Date:  1996-11       Impact factor: 4.981

5.  Thrombolytic treatment for elderly patients.

Authors:  S Arino; A Bayer
Journal:  BMJ       Date:  1992-11-21

6.  Time delay to thrombolytic therapy--a Sri Lankan perspective.

Authors:  G R Constantine; P N Thenabadu
Journal:  Postgrad Med J       Date:  1998-07       Impact factor: 2.401

7.  Fax machines for thrombolysis?

Authors:  D Chamberlain
Journal:  Heart       Date:  1997-08       Impact factor: 5.994

8.  Selection factors for the use of thrombolytic treatment in acute myocardial infarction: a population based study of current practice in the United Kingdom. The European Secondary Prevention Study Group.

Authors:  D Ketley; K L Woods
Journal:  Br Heart J       Date:  1995-09

9.  The use of audit to set up a thrombolysis programme in the accident and emergency department.

Authors:  J M Kendall; S E McCabe
Journal:  J Accid Emerg Med       Date:  1996-01

10.  One-year prospective study of cases of suspected acute myocardial infarction managed by urban and rural general practitioners.

Authors:  A W Murphy; D McCafferty; J Dowling; G Bury
Journal:  Br J Gen Pract       Date:  1996-02       Impact factor: 5.386

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