Literature DB >> 8821229

The use of audit to set up a thrombolysis programme in the accident and emergency department.

J M Kendall1, S E McCabe.   

Abstract

OBJECTIVE: To improve the thrombolysis service offered by Gloucester Royal Hospital, by reducing the "door to needle time" (DTN) to 30 min (from a median of 110 min), and increasing the proportion of patients with acute myocardial infarctions receiving thrombolysis to 70% (from 58%). This would be achieved by moving the thrombolysis programme from the coronary care unit (CCU) to the accident and emergency (A&E) department.
DESIGN: The process of audit was used to identify an area of poor performance, set standards, acquire funding, demonstrate achievement, and subsequently secure recurrent funding.
SETTING: Gloucester Royal Hospital.
SUBJECTS: 946 patients presenting consecutively to the A&E department with non-traumatic chest pain between August 1993 and March 1994. MAIN OUTCOME MEASURES: DTN, overall delay time, and acute myocardial infarction thrombolysis rate.
RESULTS: 946 patients were assessed over the eight month period, of whom 266 (28%) had suffered an acute myocardial infarction; 182 (68%) received thrombolysis (compared to 58% previously P < 0.05). Median DTN was reduced to 38 min (v 110 min previously, P < 0.0006). 127 (70%) patients received thrombolysis in the A&amp;E department, and 55 (30%) in the CCU. Median overall delay time between onset of pain and thrombolysis was 3 h 35 min; 70% of patients received thrombolysis within 6 h of onset of symptoms and 90% within 12 h. Re-audit has subsequently shown maintenance of improvement.
CONCLUSIONS: An in-house A&amp;E based thrombolysis programme works in the District General Hospital setting; the process of audit can be used to acquire, and subsequently secure, funding for the project. The key to successful implementation of change is sensible resource allocation into adequate staffing and appropriate education.

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Mesh:

Year:  1996        PMID: 8821229      PMCID: PMC1342610          DOI: 10.1136/emj.13.1.49

Source DB:  PubMed          Journal:  J Accid Emerg Med        ISSN: 1351-0622


  11 in total

1.  Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction. Anglo-Scandinavian Study of Early Thrombolysis (ASSET).

Authors:  R G Wilcox; G von der Lippe; C G Olsson; G Jensen; A M Skene; J R Hampton
Journal:  Lancet       Date:  1988-09-03       Impact factor: 79.321

2.  Thrombolysis in myocardial infarction.

Authors:  S M Cobbe
Journal:  BMJ       Date:  1994-01-22

3.  The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs.

Authors:  K A Reimer; J E Lowe; M M Rasmussen; R B Jennings
Journal:  Circulation       Date:  1977-11       Impact factor: 29.690

Review 4.  The electrocardiographic diagnosis of acute myocardial infarction in the thrombolytic era.

Authors:  P Schweitzer
Journal:  Am Heart J       Date:  1990-03       Impact factor: 4.749

5.  An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction.

Authors: 
Journal:  N Engl J Med       Date:  1993-09-02       Impact factor: 91.245

6.  Temporal dependence of beneficial effects of coronary thrombolysis characterized by positron tomography.

Authors:  S R Bergmann; R A Lerch; K A Fox; P A Ludbrook; M J Welch; M M Ter-Pogossian; B E Sobel
Journal:  Am J Med       Date:  1982-10       Impact factor: 4.965

7.  Time delays in provision of thrombolytic treatment in six district hospitals. Joint Audit Committee of the British Cardiac Society and a Cardiology Committee of Royal College of Physicians of London.

Authors:  J S Birkhead
Journal:  BMJ       Date:  1992-08-22

8.  Earliest electrocardiographic evidence of myocardial infarction: implications for thrombolytic treatment. The GREAT Group.

Authors:  J Adams; R Trent; J Rawles
Journal:  BMJ       Date:  1993-08-14

9.  Thrombolysis for acute myocardial infarction in a district general hospital.

Authors:  H Dalton; D Chappel; R Climie
Journal:  J R Soc Med       Date:  1989-07       Impact factor: 18.000

10.  Delay in presentation after myocardial infarction.

Authors:  A G Heriot; S J Brecker; D J Coltart
Journal:  J R Soc Med       Date:  1993-11       Impact factor: 18.000

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  5 in total

Review 1.  A review of interventions and system changes to improve time to reperfusion for ST-segment elevation myocardial infarction.

Authors:  Kelly A McDermott; Christian D Helfrich; Anne E Sales; John S Rumsfeld; P Michael Ho; Stephan D Fihn
Journal:  J Gen Intern Med       Date:  2008-05-06       Impact factor: 5.128

Review 2.  Audit: how to do it in practice.

Authors:  Andrea Benjamin
Journal:  BMJ       Date:  2008-05-31

3.  Changing the site of delivery of thrombolytic treatment for acute myocardial infarction from the coronary care unit to the emergency department greatly reduces door to needle time.

Authors:  C T Hourigan; D Mountain; P E Langton; I G Jacobs; I R Rogers; G A Jelinek; P L Thompson
Journal:  Heart       Date:  2000-08       Impact factor: 5.994

4.  Identifying barriers to prehospital thrombolysis in the treatment of acute myocardial infarction.

Authors:  T C Hanson; D Williamson
Journal:  Emerg Med J       Date:  2006-08       Impact factor: 2.740

5.  Nurse initiated thrombolysis in the accident and emergency department: safe, accurate, and faster than fast track.

Authors:  S M Heath; R J I Bain; A Andrews; S Chida; S I Kitchen; M I Walters
Journal:  Emerg Med J       Date:  2003-09       Impact factor: 2.740

  5 in total

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