Literature DB >> 1372266

Correlation between car ownership and leukaemia: is non-occupational exposure to benzene from petrol and motor vehicle exhaust a causative factor in leukaemia and lymphoma?

S P Wolff1.   

Abstract

Although there is widespread agreement that many cancers have environmental causes we are often unable to see associations between specific cancers and exposure to environmental chemicals. One might also speculate that the more widespread, common-place and 'normal' a chemical exposure is perceived to be then the less likely it will be that the exposure is recognised, let alone be considered to cause cancer. Widespread contamination of air by chemicals associated with internal combustion may be an example of one such 'invisible' carcinogenic exposure. Yet evidence is available which suggests that many leukaemia and lymphoma cases, as well as other cancers, may be caused by this mundane and ubiquitous environmental contamination. The hypothesis is developed that leukaemia 'clustering' as well as national leukaemia incidence may be related to non-occupational exposure to benzene formed by petrol combustion and resulting from petrol evaporation. The possible association between exposure to fuel vapours, internal combustion products and cancer merits much closer examination than it receives at present.

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Year:  1992        PMID: 1372266     DOI: 10.1007/bf01930480

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  30 in total

1.  Radiation exposure. Sellafield under scrutiny.

Authors:  P Aldhous
Journal:  Nature       Date:  1990-10-11       Impact factor: 49.962

2.  The real role of risk assessment in cancer risk management.

Authors:  W K Lutz; J Poetzsch; J Schlatter; C Schlatter
Journal:  Trends Pharmacol Sci       Date:  1991-06       Impact factor: 14.819

3.  Child leukaemia--curies or cars?

Authors:  S P Wolff
Journal:  Nature       Date:  1990-08-09       Impact factor: 49.962

4.  Lymphomas and benzene.

Authors:  P E Enterline
Journal:  Lancet       Date:  1979-11-10       Impact factor: 79.321

5.  [Cancer in residents of heavy traffic areas].

Authors:  M Ippen; R Fehr; E O Krasemann
Journal:  Versicherungsmedizin       Date:  1989-03-01

6.  Association of childhood cancer with residential traffic density.

Authors:  D A Savitz; L Feingold
Journal:  Scand J Work Environ Health       Date:  1989-10       Impact factor: 5.024

Review 7.  Projections of leukemia risk associated with occupational exposure to benzene.

Authors:  P F Infante; M C White
Journal:  Am J Ind Med       Date:  1985       Impact factor: 2.214

8.  Benzene and leukemia. An epidemiologic risk assessment.

Authors:  R A Rinsky; A B Smith; R Hornung; T G Filloon; R J Young; A H Okun; P J Landrigan
Journal:  N Engl J Med       Date:  1987-04-23       Impact factor: 91.245

9.  International trends in cancer mortality in France, West Germany, Italy, Japan, England and Wales, and the USA.

Authors:  D L Davis; D Hoel; J Fox; A Lopez
Journal:  Lancet       Date:  1990-08-25       Impact factor: 79.321

10.  Geographical variation in mortality from leukaemia and other cancers in England and Wales in relation to proximity to nuclear installations, 1969-78.

Authors:  P J Cook-Mozaffari; S C Darby; R Doll; D Forman; C Hermon; M C Pike; T Vincent
Journal:  Br J Cancer       Date:  1989-03       Impact factor: 7.640

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  6 in total

1.  Analysis of incidence of childhood cancer in the West Midlands of the United Kingdom in relation to proximity to main roads and petrol stations.

Authors:  R M Harrison; P L Leung; L Somervaille; R Smith; E Gilman
Journal:  Occup Environ Med       Date:  1999-11       Impact factor: 4.402

2.  Lymphohaematopoietic system cancer incidence in an urban area near a coke oven plant: an ecological investigation.

Authors:  S Parodi; M Vercelli; A Stella; E Stagnaro; F Valerio
Journal:  Occup Environ Med       Date:  2003-03       Impact factor: 4.402

Review 3.  Too easily lead? Health effects of gasoline additives.

Authors:  D B Menkes; J P Fawcett
Journal:  Environ Health Perspect       Date:  1997-03       Impact factor: 9.031

Review 4.  Integrated defense system overlaps as a disease model: with examples for multiple chemical sensitivity.

Authors:  S C Rowat
Journal:  Environ Health Perspect       Date:  1998-02       Impact factor: 9.031

5.  Environmental and biological monitoring of benzene during self-service automobile refueling.

Authors:  P P Egeghy; R Tornero-Velez; S M Rappaport
Journal:  Environ Health Perspect       Date:  2000-12       Impact factor: 9.031

Review 6.  Childhood cancer: overview of incidence trends and environmental carcinogens.

Authors:  S H Zahm; S S Devesa
Journal:  Environ Health Perspect       Date:  1995-09       Impact factor: 9.031

  6 in total

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