Literature DB >> 1335438

Recruitment of dorsal column fibers in spinal cord stimulation: influence of collateral branching.

J J Struijk1, J Holsheimer, G G van der Heide, H B Boom.   

Abstract

An electrical network model of myelinated dorsal column nerve fibers is presented. The effect of electrical stimulation was investigated using both a homogeneous volume conductor and a more realistic model of the spinal cord. An important feature of dorsal column nerve fibers is the presence of myelinated collaterals perpendicular to the rostro-caudal fibers. It was found that transmembrane potentials, due to external monopolar stimulation, at the node at which a collateral is attached, is significantly influenced by the presence of the collateral. It is concluded that both excitation threshold and blocking threshold of dorsal column fibers are decreased up to 50% compared to unbranched fibers.

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Year:  1992        PMID: 1335438     DOI: 10.1109/10.256423

Source DB:  PubMed          Journal:  IEEE Trans Biomed Eng        ISSN: 0018-9294            Impact factor:   4.538


  36 in total

1.  Magnetic and electrical stimulation of undulating nerve fibres: a simulation study.

Authors:  V Schnabel; J J Struijk
Journal:  Med Biol Eng Comput       Date:  1999-11       Impact factor: 2.602

2.  Determining which mechanisms lead to activation in the motor cortex: a modeling study of transcranial magnetic stimulation using realistic stimulus waveforms and sulcal geometry.

Authors:  R Salvador; S Silva; P J Basser; P C Miranda
Journal:  Clin Neurophysiol       Date:  2010-10-28       Impact factor: 3.708

Review 3.  Restoration of locomotive function in Parkinson's disease by spinal cord stimulation: mechanistic approach.

Authors:  Romulo Fuentes; Per Petersson; Miguel A L Nicolelis
Journal:  Eur J Neurosci       Date:  2010-10       Impact factor: 3.386

4.  Modelling motor cortex stimulation for chronic pain control: electrical potential field, activating functions and responses of simple nerve fibre models.

Authors:  L Manola; B H Roelofsen; J Holsheimer; E Marani; J Geelen
Journal:  Med Biol Eng Comput       Date:  2005-05       Impact factor: 2.602

5.  The "mirror" estimate: an intuitive predictor of membrane polarization during extracellular stimulation.

Authors:  Sébastien Joucla; Blaise Yvert
Journal:  Biophys J       Date:  2009-05-06       Impact factor: 4.033

6.  Transverse tripolar stimulation of peripheral nerve: a modelling study of spatial selectivity.

Authors:  K E Deurloo; J Holsheimer; H B Boom
Journal:  Med Biol Eng Comput       Date:  1998-01       Impact factor: 2.602

7.  Optimum electrode geometry for spinal cord stimulation: the narrow bipole and tripole.

Authors:  J Holsheimer; W A Wesselink
Journal:  Med Biol Eng Comput       Date:  1997-09       Impact factor: 2.602

8.  The extracellular potential of a myelinated nerve fiber in an unbounded medium and in nerve cuff models.

Authors:  J J Struijk
Journal:  Biophys J       Date:  1997-06       Impact factor: 4.033

9.  Transverse tripolar spinal cord stimulation: theoretical performance of a dual channel system.

Authors:  J J Struijk; J Holsheimer
Journal:  Med Biol Eng Comput       Date:  1996-07       Impact factor: 2.602

10.  Comparison of spinal cord stimulation profiles from intra- and extradural electrode arrangements by finite element modelling.

Authors:  Qiujun Huang; Hiroyuki Oya; Oliver E Flouty; Chandan G Reddy; Matthew A Howard; George T Gillies; Marcel Utz
Journal:  Med Biol Eng Comput       Date:  2014-04-27       Impact factor: 2.602

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