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Literature DB >> 12948779

Designing redox metalloproteins from bottom-up and top-down perspectives.

Abstract

The design of redox-active metalloproteins has been approached from two different directions. The de novo design approach has recently reached an important stage, at which structural information on several different designed metalloproteins has been obtained. This new information highlights the real challenge of this approach. The alternative approach involving re-engineering of evolved proteins has also made significant advances recently.

Mesh：

Substances：
Metalloproteins

Year: 2003 PMID： 12948779 DOI： 10.1016/s0959-440x(03)00108-8

Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809

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Cited

15 in total

1. Light-driven oxygen production from superoxide by Mn-binding bacterial reaction centers.

Authors: James P Allen; Tien L Olson; Paul Oyala; Wei-Jen Lee; Aaron A Tufts; JoAnn C Williams
Journal: Proc Natl Acad Sci U S A Date: 2012-01-30 Impact factor: 11.205

2. Designing functional metalloproteins: from structural to catalytic metal sites.

Authors: Melissa L Zastrow; Vincent L Pecoraro
Journal: Coord Chem Rev Date: 2013-09 Impact factor: 22.315

3. Design of amphiphilic protein maquettes: enhancing maquette functionality through binding of extremely hydrophobic cofactors to lipophilic domains.

Authors: Dror Noy; Bohdana M Discher; Igor V Rubtsov; Robin M Hochstrasser; P Leslie Dutton
Journal: Biochemistry Date: 2005-09-20 Impact factor: 3.162

4. Metalloprotein and metallo-DNA/RNAzyme design: current approaches, success measures, and future challenges.

Authors: Yi Lu
Journal: Inorg Chem Date: 2006-12-11 Impact factor: 5.165

5. Experimental and theoretical study of the mechanism of hydrolysis of substituted phenyl hexanoates catalysed by globin in the presence of surfactant.

Authors: Selami Ercan; Nevin Arslan; Safak Ozhan Kocakaya; Necmettin Pirinccioglu; Andrew Williams
Journal: J Mol Model Date: 2014-02-22 Impact factor: 1.810

Designing redox metalloproteins from bottom-up and top-down perspectives.

1. Light-driven oxygen production from superoxide by Mn-binding bacterial reaction centers.

2. Designing functional metalloproteins: from structural to catalytic metal sites.

3. Design of amphiphilic protein maquettes: enhancing maquette functionality through binding of extremely hydrophobic cofactors to lipophilic domains.

4. Metalloprotein and metallo-DNA/RNAzyme design: current approaches, success measures, and future challenges.

5. Experimental and theoretical study of the mechanism of hydrolysis of substituted phenyl hexanoates catalysed by globin in the presence of surfactant.

Review 6. Protein design: toward functional metalloenzymes.

7. Incorporating electron-transfer functionality into synthetic metalloproteins from the bottom-up.

8. De Novo Design of an Allosteric Metalloprotein Assembly with Strained Disulfide Bonds.

9. Computational design of receptors for an organophosphate surrogate of the nerve agent soman.

Review 10. Design of functional metalloproteins.