AIMS: To find the cure rate of late (second year of age) and very late (3-5 years of age) initial probing for congenital nasolacrimal duct obstruction (CNLDO) and to identify the factors contributing to the failure rate of the probing in older children. METHODS: In a prospective interventional case series study, 169 eyes of 125 consecutive patients (1-5 years old) with CNLDO underwent probing under general anaesthesia. Cure was defined as absence of tearing and discharge in the affected eye. RESULTS: 138 eyes of 101 patients aged 13-60 months (mean 23.4 (SD 10.2)) were included. Of 15 eyes (10.8%) with complex CNLDO, 80% presented after 24 months of age (p<0.0001). The cure rate was 89% in patients 13-24 months of age and 72% after the age of 24 months (p = 0.01). It was 90.2% in the membranous and 33.3% in the complex CNLDO in both late and very late probing (p<0.0001). There was a high correlation (r = 0.97) and no significant difference between the cure rate at 1 week and final follow up. CONCLUSION: Accumulation of the complex CNLDO is the main risk factor for failure of probing in the older children. The outcome of the nasolacrimal duct probing at 1 week follow up is highly indicative of the final outcome.
AIMS: To find the cure rate of late (second year of age) and very late (3-5 years of age) initial probing for congenital nasolacrimal duct obstruction (CNLDO) and to identify the factors contributing to the failure rate of the probing in older children. METHODS: In a prospective interventional case series study, 169 eyes of 125 consecutive patients (1-5 years old) with CNLDO underwent probing under general anaesthesia. Cure was defined as absence of tearing and discharge in the affected eye. RESULTS: 138 eyes of 101 patients aged 13-60 months (mean 23.4 (SD 10.2)) were included. Of 15 eyes (10.8%) with complex CNLDO, 80% presented after 24 months of age (p<0.0001). The cure rate was 89% in patients 13-24 months of age and 72% after the age of 24 months (p = 0.01). It was 90.2% in the membranous and 33.3% in the complex CNLDO in both late and very late probing (p<0.0001). There was a high correlation (r = 0.97) and no significant difference between the cure rate at 1 week and final follow up. CONCLUSION: Accumulation of the complex CNLDO is the main risk factor for failure of probing in the older children. The outcome of the nasolacrimal duct probing at 1 week follow up is highly indicative of the final outcome.
Authors: Jonathan M Holmes; David A Leske; Stephen R Cole; Danielle L Chandler; Michael X Repka; David I Silbert; David Robbins Tien; Elizabeth A Bradley; Nicholas A Sala; Erika M Levin; Darren L Hoover; Deborah L Klimek; Brian G Mohney; Daniel M Laby; Katherine A Lee; Robert W Enzenauer; Darron A Bacal; Monte D Mills; Roy W Beck Journal: Ophthalmology Date: 2006-07-07 Impact factor: 12.079
Authors: Michael X Repka; Danielle L Chandler; Roy W Beck; Eric R Crouch; Sean Donahue; Jonathan M Holmes; Katherine Lee; Michele Melia; Graham E Quinn; Nick A Sala; Susan Schloff; David I Silbert; David K Wallace Journal: Ophthalmology Date: 2007-11-08 Impact factor: 12.079
Authors: Michael X Repka; B Michele Melia; Roy W Beck; Danielle L Chandler; Deborah R Fishman; Todd A Goldblum; Jonathan M Holmes; Bernard D Perla; Graham E Quinn; David I Silbert; David K Wallace Journal: J AAPOS Date: 2008-10 Impact factor: 1.220
Authors: Michael X Repka; B Michele Melia; Roy W Beck; C Scott Atkinson; Danielle L Chandler; Jonathan M Holmes; Alexander Khammar; David Morrison; Graham E Quinn; David I Silbert; Benjamin H Ticho; David K Wallace; David R Weakley Journal: J AAPOS Date: 2008-07-02 Impact factor: 1.220