Literature DB >> 12904816

Drug research: myths, hype and reality.

Hugo Kubinyi1.   

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Year:  2003        PMID： 12904816     DOI： 10.1038/nrd1156

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  45 in total

1.  Advances in Nuclear Magnetic Resonance for Drug Discovery.

Authors:  Robert Powers
Journal:  Expert Opin Drug Discov       Date:  2009-10-01       Impact factor: 6.098

2.  Reductionism and complexity in molecular biology. Scientists now have the tools to unravel biological and overcome the limitations of reductionism.

Authors:  Marc H V Van Regenmortel
Journal:  EMBO Rep       Date:  2004-11       Impact factor: 8.807

3.  Determining the optimal size of small molecule mixtures for high throughput NMR screening.

Authors:  Kelly A Mercier; Robert Powers
Journal:  J Biomol NMR       Date:  2005-03       Impact factor: 2.835

4.  VeloceGenomics: an accelerated in vivo drug discovery approach to rapidly predict the biologic, drug-like activity of compounds, proteins, or genes.

Authors:  Ruben Papoian; Andreas Scherer; Muriel Saulnier; Frank Staedtler; André Cordier; Francois Legay; Gerard Maurer; Joerg Staeheli; Jacky Vonderscher; Salah-Dine Chibout
Journal:  Pharm Res       Date:  2005-09-22       Impact factor: 4.200

Review 5.  Computer-aided drug discovery and development (CADDD): in silico-chemico-biological approach.

Authors:  I M Kapetanovic
Journal:  Chem Biol Interact       Date:  2006-12-16       Impact factor: 5.192

6.  Arylsulfanyl pyrazolones block mutant SOD1-G93A aggregation. Potential application for the treatment of amyotrophic lateral sclerosis.

Authors:  Tian Chen; Radhia Benmohamed; Anthony C Arvanites; Hantamalala Ralay Ranaivo; Richard I Morimoto; Robert J Ferrante; D Martin Watterson; Donald R Kirsch; Richard B Silverman
Journal:  Bioorg Med Chem       Date:  2010-10-30       Impact factor: 3.641

Review 7.  Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery.

Authors:  Mohammad S Alavijeh; Mansoor Chishty; M Zeeshan Qaiser; Alan M Palmer
Journal:  NeuroRx       Date:  2005-10

Review 8.  The application of FAST-NMR for the identification of novel drug discovery targets.

Authors:  Robert Powers; Kelly A Mercier; Jennifer C Copeland
Journal:  Drug Discov Today       Date:  2008-02       Impact factor: 7.851

Review 9.  Fragment-based QSAR: perspectives in drug design.

Authors:  Lívia B Salum; Adriano D Andricopulo
Journal:  Mol Divers       Date:  2009-01-31       Impact factor: 2.943

10.  A high-throughput 1,536-well luminescence assay for glutathione S-transferase activity.

Authors:  Adam Yasgar; John Shultz; Wenhui Zhou; Hui Wang; Fen Huang; Nancy Murphy; Erika L Abel; John DiGiovanni; James Inglese; Anton Simeonov
Journal:  Assay Drug Dev Technol       Date:  2010-04       Impact factor: 1.738
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