Literature DB >> 12796441

Non-heart beating organ donation: old procurement strategy--new ethical problems.

M D D Bell1.   

Abstract

The imbalance between supply of organs for transplantation and demand for them is widening. Although the current international drive to re-establish procurement via non-heart beating organ donation/donor (NHBOD) is founded therefore on necessity, the process may constitute a desirable outcome for patient and family when progression to brain stem death (BSD) does not occur and conventional organ retrieval from the beating heart donor is thereby prevented. The literature accounts of this practice, however, raise concerns that risk jeopardising professional and public confidence in the broader transplant programme. This article focuses on these clinical, ethical, and legal issues in the context of other approaches aimed at increasing donor numbers. The feasibility of introducing such an initiative will hinge on the ability to reassure patients, families, attendant staff, professional bodies, the wider public, law enforcement agencies, and the media that practitioners are working within explicit guidelines which are both ethically and legally defensible.

Entities:  

Keywords:  Death and Euthanasia; Health Care and Public Health

Mesh:

Year:  2003        PMID: 12796441      PMCID: PMC1733729          DOI: 10.1136/jme.29.3.176

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  58 in total

1.  The trouble with kidneys derived from the non heart-beating donor: a single center 10-year experience.

Authors:  S Balupuri; P Buckley; C Snowden; M Mustafa; B Sen; P Griffiths; M Hannon; D Manas; J Kirby; D Talbot
Journal:  Transplantation       Date:  2000-03-15       Impact factor: 4.939

2.  Anaesthesia for organ donation in the brainstem dead--why bother?

Authors:  P J Young; B F Matta
Journal:  Anaesthesia       Date:  2000-02       Impact factor: 6.955

3.  Nondirected donation of kidneys from living donors.

Authors:  A J Matas; C A Garvey; C L Jacobs; J P Kahn
Journal:  N Engl J Med       Date:  2000-08-10       Impact factor: 91.245

Review 4.  Is xenotransplantation a realistic clinical option?

Authors:  D K Cooper
Journal:  Transplant Proc       Date:  1992-12       Impact factor: 1.066

5.  Non--heart-beating donors: an alternative organ source in kidney transplantation.

Authors:  P Rigotti; E Morpurgo; M G Comandella; G Pittoni; N Baldan; E Ganz; L Piazza; M Capalbo; M L Valente; E Ancona
Journal:  Transplant Proc       Date:  1991-10       Impact factor: 1.066

6.  Detrimental effects of brain death on the potential organ donor.

Authors:  D Novitzky
Journal:  Transplant Proc       Date:  1997-12       Impact factor: 1.066

7.  Statement on non-heart-beating donor programs.

Authors:  G Kootstra
Journal:  Transplant Proc       Date:  1995-10       Impact factor: 1.066

8.  The use of liver grafts from donors with bacterial meningitis.

Authors:  S Satoi; S R Bramhall; M Solomon; M Hastings; A D Mayer; J V de Goyet; J A Buckels; P McMaster; D F Mirza
Journal:  Transplantation       Date:  2001-09-27       Impact factor: 4.939

9.  Public policy governing organ and tissue procurement in the United States. Results from the National Organ and Tissue Procurement Study.

Authors:  L A Siminoff; R M Arnold; A L Caplan; B A Virnig; D L Seltzer
Journal:  Ann Intern Med       Date:  1995-07-01       Impact factor: 25.391

10.  Improved cerebral resuscitation from cardiac arrest in dogs with mild hypothermia plus blood flow promotion.

Authors:  P Safar; F Xiao; A Radovsky; K Tanigawa; U Ebmeyer; N Bircher; H Alexander; S W Stezoski
Journal:  Stroke       Date:  1996-01       Impact factor: 7.914

View more
  10 in total

Review 1.  The UK Human Tissue Act and consent: surrendering a fundamental principle to transplantation needs?

Authors:  M D D Bell
Journal:  J Med Ethics       Date:  2006-05       Impact factor: 2.903

Review 2.  Emergency medicine, organ donation and the Human Tissue Act.

Authors:  M D D Bell
Journal:  Emerg Med J       Date:  2006-11       Impact factor: 2.740

3.  Neurointensivists' opinions about death by neurological criteria and organ donation.

Authors:  Adrienne R Boissy; J Javier Provencio; Cheryl A Smith; Michael N Diringer
Journal:  Neurocrit Care       Date:  2005       Impact factor: 3.210

4.  A Comparison of Request Process and Outcomes in Donation After Cardiac Death and Donation After Brain Death: Results From a National Study.

Authors:  L A Siminoff; G P Alolod; M Wilson-Genderson; E Y N Yuen; H M Traino
Journal:  Am J Transplant       Date:  2016-11-21       Impact factor: 8.086

5.  In defense of the reverence of all life: Heideggerean dissolution of the ethical challenges of organ donation after circulatory determination of death.

Authors:  D J Isch
Journal:  Med Health Care Philos       Date:  2007-05-02

6.  Are terminally ill patients dying in the ICU suitable for non-heart beating organ donation?

Authors:  Jean-Pierre Revelly; Luca Imperatori; Philippe Maravic; Marie-Denise Schaller; René Chioléro
Journal:  Intensive Care Med       Date:  2006-03-14       Impact factor: 17.440

7.  A case of kidney transplantation using donation after circulatory death with renal calculi.

Authors:  Baoshan Gao; Kun Zhang; Chunjie Guo; Weigang Wang; Gang Wang; Yuantao Wang; Liyu Yao; Yaowen Fu; Honglan Zhou
Journal:  Int J Clin Exp Med       Date:  2015-11-15

8.  Donation after cardiocirculatory death: a call for a moratorium pending full public disclosure and fully informed consent.

Authors:  Ari R Joffe; Joe Carcillo; Natalie Anton; Allan deCaen; Yong Y Han; Michael J Bell; Frank A Maffei; John Sullivan; James Thomas; Gonzalo Garcia-Guerra
Journal:  Philos Ethics Humanit Med       Date:  2011-12-29       Impact factor: 2.464

9.  Awareness of Religious Leaders' Fatwa and Willingness to Donate Organ.

Authors:  M Afzal Aghaee; M Dehghani; M Sadeghi; E Khaleghi
Journal:  Int J Organ Transplant Med       Date:  2015-11-01

10.  Awareness and attitudes toward corneal donation among applicants and staff of a driver, vehicle and licensing authority (DVLA) in Ghana.

Authors:  Seth Lartey; Ellen K Antwi-Adjei; Solomon Agyapong; Abdul-Kabir Mohammed; Derrick N O Mensah; Edward S Genego
Journal:  BMC Ophthalmol       Date:  2019-11-12       Impact factor: 2.209

  10 in total

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