Literature DB >> 26885172

A case of kidney transplantation using donation after circulatory death with renal calculi.

Baoshan Gao1, Kun Zhang1, Chunjie Guo2, Weigang Wang1, Gang Wang1, Yuantao Wang1, Liyu Yao1, Yaowen Fu1, Honglan Zhou1.   

Abstract

Donation after circulatory death (DCD) supplies a big percentage of the organ source pool. Compared to living-related donations, donor kidneys from DCD are commonly with lower quality since they inevitably suffer from hypoxia, hypotension, and inadequate organ perfusion during the progression to circulatory arrest. The current case presents a 44-year-old male donor with wide range subarachnoid hemorrhage and multiple skull fracture from a car accident. Multiple stones were detected in his right kidney. We performed a modified ex vivo pyelolithotomy and ureteroscopy on the bench to render a stone-free allograft. We also improved the donor kidney with hypothermic/perfusion preservation machine before renal transplantation. The recipient showed no complications during the first two-month post-operational follow-up. Such a donor kidney with stones may probably be discarded by conventional perspective. Yet, the combination of the ex vivo bench-surgery technique and hypothermic oxygenation/perfusion makes it a qualified donor kidney. Thus we have demonstrated a promising way of saving borderline qualified DCD donor kidneys.

Entities:  

Keywords:  Donation after circulatory death; kidney transplantation; pyelolithotomy; renal calculi; ureteroscopy

Year:  2015        PMID: 26885172      PMCID: PMC4724018     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  14 in total

1.  Ex vivo ureteroscopic treatment of calculi in donor kidneys at renal transplantation.

Authors:  Michael G Rashid; John W Konnak; J Stuart Wolf; Jeffery D Punch; John C Magee; Juan D Arenas; Gary J Faerber
Journal:  J Urol       Date:  2004-01       Impact factor: 7.450

Review 2.  Non-heart beating organ donation: overview and future perspectives.

Authors:  Cyril Moers; Henri G D Leuvenink; Rutger J Ploeg
Journal:  Transpl Int       Date:  2007-01-30       Impact factor: 3.782

3.  Development of extracorporeal renal perfusion as an adjunct for bench renal surgery.

Authors:  W G Guerriero; R Scott; L Joyce
Journal:  J Urol       Date:  1972-01       Impact factor: 7.450

4.  Stone-bearing live-donor kidneys for transplantation.

Authors:  Anthony Devasia; Ninan Chacko; Lionel Gnanaraj; Rekha Cherian; Ganesh Gopalakrishnan
Journal:  BJU Int       Date:  2005-02       Impact factor: 5.588

5.  Non-heart beating organ donation: old procurement strategy--new ethical problems.

Authors:  M D D Bell
Journal:  J Med Ethics       Date:  2003-06       Impact factor: 2.903

6.  Expanded criteria donors for kidney transplantation: quality control and results.

Authors:  M A Frutos; E Sola; J J Mansilla; P Ruiz; A Martín-Gómez; G Seller
Journal:  Transplant Proc       Date:  2006-10       Impact factor: 1.066

Review 7.  The super-rapid technique in Maastricht category III donors: has it developed enough for marginal liver grafts from donors after cardiac death?

Authors:  M Thamara P R Perera
Journal:  Curr Opin Organ Transplant       Date:  2012-04       Impact factor: 2.640

8.  Protective mechanisms of end-ischemic cold machine perfusion in DCD liver grafts.

Authors:  Andrea Schlegel; Olivier de Rougemont; Rolf Graf; Pierre-Alain Clavien; Philipp Dutkowski
Journal:  J Hepatol       Date:  2012-10-11       Impact factor: 25.083

Review 9.  Donation after circulatory death: current practices, ongoing challenges, and potential improvements.

Authors:  Paul E Morrissey; Anthony P Monaco
Journal:  Transplantation       Date:  2014-02-15       Impact factor: 4.939

10.  Machine perfusion or cold storage in deceased-donor kidney transplantation.

Authors:  Cyril Moers; Jacqueline M Smits; Mark-Hugo J Maathuis; Jürgen Treckmann; Frank van Gelder; Bogdan P Napieralski; Margitta van Kasterop-Kutz; Jaap J Homan van der Heide; Jean-Paul Squifflet; Ernest van Heurn; Günter R Kirste; Axel Rahmel; Henri G D Leuvenink; Andreas Paul; Jacques Pirenne; Rutger J Ploeg
Journal:  N Engl J Med       Date:  2009-01-01       Impact factor: 91.245

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