Literature DB >> 12746498

Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription.

David A Bushnell1, Roger D Kornberg.   

Abstract

The x-ray structure of complete RNA polymerase II from Saccharomyces cerevisiae has been determined, including a heterodimer of subunits Rpb4 and Rpb7 not present in previous "core" polymerase II structures. The heterodimer maintains the polymerase in the conformation of a transcribing complex, may bind RNA as it emerges from the enzyme, and is in a position to interact with general transcription factors and the Mediator of transcriptional regulation.

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Year:  2003        PMID： 12746498      PMCID： PMC165814          DOI： 10.1073/pnas.1130601100

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  39 in total

1.  Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.

Authors:  A L Gnatt; P Cramer; J Fu; D A Bushnell; R D Kornberg
Journal:  Science       Date:  2001-04-19       Impact factor: 47.728

2.  The A14-A43 heterodimer subunit in yeast RNA pol I and their relationship to Rpb4-Rpb7 pol II subunits.

Authors:  Gerald Peyroche; Erwann Levillain; Magali Siaut; Isabelle Callebaut; Patrick Schultz; Andre Sentenac; Michel Riva; Christophe Carles
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-29       Impact factor: 11.205

Review 3.  The mRNA assembly line: transcription and processing machines in the same factory.

Authors:  David Bentley
Journal:  Curr Opin Cell Biol       Date:  2002-06       Impact factor: 8.382

4.  Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction.

Authors:  Joshua A Davis; Yuichiro Takagi; Roger D Kornberg; Francisco A Asturias
Journal:  Mol Cell       Date:  2002-08       Impact factor: 17.970

5.  Structure of yeast RNA polymerase II in solution: implications for enzyme regulation and interaction with promoter DNA.

Authors:  John L Craighead; Wei-hau Chang; Francisco J Asturias
Journal:  Structure       Date:  2002-08       Impact factor: 5.006

6.  Improved methods for building protein models in electron density maps and the location of errors in these models.

Authors:  T A Jones; J Y Zou; S W Cowan; M Kjeldgaard
Journal:  Acta Crystallogr A       Date:  1991-03-01       Impact factor: 2.290

7.  An Rpb4/Rpb7-like complex in yeast RNA polymerase III contains the orthologue of mammalian CGRP-RCP.

Authors:  Magali Siaut; Cécile Zaros; Emilie Levivier; Maria-Laura Ferri; Magali Court; Michel Werner; Isabelle Callebaut; Pierre Thuriaux; André Sentenac; Christine Conesa
Journal:  Mol Cell Biol       Date:  2003-01       Impact factor: 4.272

8.  RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth.

Authors:  N A Woychik; R A Young
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

9.  RPB7, one of two dissociable subunits of yeast RNA polymerase II, is essential for cell viability.

Authors:  K McKune; K L Richards; A M Edwards; R A Young; N A Woychik
Journal:  Yeast       Date:  1993-03       Impact factor: 3.239

10.  Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro.

Authors:  A M Edwards; C M Kane; R A Young; R D Kornberg
Journal:  J Biol Chem       Date:  1991-01-05       Impact factor: 5.157
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  114 in total

1.  RNA polymerase II at initiation.

Authors:  Francisco J Asturias; John L Craighead
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-02       Impact factor: 11.205

Review 2.  Structure and mechanism of the RNA polymerase II transcription machinery.

Authors:  Steven Hahn
Journal:  Nat Struct Mol Biol       Date:  2004-05       Impact factor: 15.369

3.  Regulated communication between the upstream face of RNA polymerase and the beta' subunit jaw domain.

Authors:  Siva R Wigneshweraraj; Patricia C Burrows; Sergei Nechaev; Nikolay Zenkin; Konstantin Severinov; Martin Buck
Journal:  EMBO J       Date:  2004-10-07       Impact factor: 11.598

4.  Mechanism of start site selection by RNA polymerase II: interplay between TFIIB and Ssl2/XPB helicase subunit of TFIIH.

Authors:  Shivani Goel; Shankarling Krishnamurthy; Michael Hampsey
Journal:  J Biol Chem       Date:  2011-11-11       Impact factor: 5.157

5.  One-step DNA melting in the RNA polymerase cleft opens the initiation bubble to form an unstable open complex.

Authors:  Theodore J Gries; Wayne S Kontur; Michael W Capp; Ruth M Saecker; M Thomas Record
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-18       Impact factor: 11.205

6.  Highly reproducible label free quantitative proteomic analysis of RNA polymerase complexes.

Authors:  Amber L Mosley; Mihaela E Sardiu; Samantha G Pattenden; Jerry L Workman; Laurence Florens; Michael P Washburn
Journal:  Mol Cell Proteomics       Date:  2010-11-03       Impact factor: 5.911

7.  Reconstitution in cultured cells of replicating HDV RNA from pairs of less than full-length RNAs.

Authors:  Severin O Gudima; Jinhong Chang; John M Taylor
Journal:  RNA       Date:  2004-12-01       Impact factor: 4.942

Review 8.  Sub1/PC4, a multifaceted factor: from transcription to genome stability.

Authors:  Miguel Garavís; Olga Calvo
Journal:  Curr Genet       Date:  2017-05-31       Impact factor: 3.886

9.  Functional interaction between TFIIB and the Rpb2 subunit of RNA polymerase II: implications for the mechanism of transcription initiation.

Authors:  Bo-Shiun Chen; Michael Hampsey
Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272

10.  A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p.

Authors:  Fan Zhang; Laarni Sumibcay; Alan G Hinnebusch; Mark J Swanson
Journal:  Mol Cell Biol       Date:  2004-08       Impact factor: 4.272
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